Search Results - "Holtzman, G"

Growth and maturation in the zebrafish, Danio rerio: a staging tool for teaching and research by Singleman, Corinna, Holtzman, Nathalia G

“…Zebrafish have been increasingly used as a teaching tool to enhance the learning of many biological concepts from genetics, development, and behavior to the…”
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Analysis of postembryonic heart development and maturation in the zebrafish, Danio rerio by Singleman, Corinna, Holtzman, Nathalia G.

“…Background: Cardiac maturation is vital for animal survival and must occur throughout the animal's life. Zebrafish are increasingly used to model cardiac…”
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Red cell distribution width as a new prognostic biomarker in refractory chronic graft- versus -host disease by Schulz, Eduard, Pirsl, Filip, Holtzman, Noa G, Beshensky, David, Cowen, Edward W, Mitchell, Sandra A, Steinberg, Seth M, Pavletic, Steven Z

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Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant by Pavel, Mahmud Arif, Lv, Caixia, Ng, Courtney, Yang, Lei, Kashyap, Parul, Lam, Clarissa, Valentino, Victoria, Fung, Helen Y., Campbell, Thomas, Møller, Simon Geir, Zenisek, David, Holtzman, Nathalia G., Yu, Yong

“…Mutations in polycystin-1 and transient receptor potential polycystin 2 (TRPP2) account for almost all clinically identified cases of autosomal dominant…”
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A randomized phase 2 trial of pomalidomide in subjects failing prior therapy for chronic graft-versus-host disease by Curtis, Lauren M., Ostojic, Alen, Venzon, David J., Holtzman, Noa G., Pirsl, Filip, Kuzmina, Zoya J., Baird, Kristin, Rose, Jeremy J., Cowen, Edward W., Mays, Jacqueline W., Mitchell, Sandra A., Parsons-Wandell, Laura, Joe, Galen O., Comis, Leora E., Berger, Ann, Pusic, Iskra, Peer, Cody J., Figg, William D., Cao, Liang, Gale, Robert Peter, Hakim, Frances T., Pavletic, Steven Z.

“…Steroid-refractory chronic graft-versus-host disease (cGVHD) is a therapeutic challenge. Sclerotic skin manifestations are especially difficult to treat. We…”
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Plasma Environment, Radiation, Structure, and Evolution of the Uranian System (PERSEUS): A Dedicated Orbiter Mission Concept to Study Space Physics at Uranus by Cohen, Ian J., Smith, Evan J., Clark, George B., Turner, Drew L., Ellison, Donald H., Clare, Ben, Regoli, Leonardo H., Kollmann, Peter, Gallagher, Daniel T., Holtzman, G. Allan, Likar, Justin J., Morizono, Takeshi, Shannon, Matthew, Vodusek, Kimberly S.

“…The Plasma Environment, Radiation, Structure, and Evolution of the Uranian System (PERSEUS) mission concept defines the feasibility and potential scope of a…”
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Integration of nodal and BMP signals in the heart requires FoxH1 to create left-right differences in cell migration rates that direct cardiac asymmetry by Lenhart, Kari F, Holtzman, Nathalia G, Williams, Jessica R, Burdine, Rebecca D

“…Failure to properly establish the left-right (L/R) axis is a major cause of congenital heart defects in humans, but how L/R patterning of the embryo leads to…”
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Aspartate β-Hydroxylase (ASPH) Expression in Acute Myeloid Leukemia: A Potential Novel Therapeutic Target by Holtzman, Noa G, Lebowitz, Michael S, Koka, Rima, Baer, Maria R, Malhotra, Kanam, Shahlaee, Amir, Ghanbari, Hossein A, Bentzen, Søren M, Emadi, Ashkan

“…Aspartate β-hydroxylase (ASPH) is an embryonic transmembrane protein aberrantly upregulated in cancer cells, associated with malignant transformation and, in…”
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Direct and indirect roles for Nodal signaling in two axis conversions during asymmetric morphogenesis of the zebrafish heart by Baker, Kari, Holtzman, Nathalia G, Burdine, Rebecca D

“…The Nodal signaling pathway plays a conserved role in determining left-sided identity in vertebrates with this early left-right (L/R) patterning influencing…”
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Long-lasting changes in stress-induced corticosterone response and anxiety-like behaviors as a consequence of neonatal maternal separation in Long–Evans rats by Kalinichev, Mikhail, Easterling, Keith W, Plotsky, Paul M, Holtzman, Stephen G

“…Early neonatal environmental factors appear to have powerful and long-lasting influences on an organism's physiology and behavior. Long–Evans male rats…”
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Forest Restoration Potentials of Coal‐Mined Lands in the Eastern United States by Zipper, C. E., Burger, J. A., McGrath, J. M., Rodrigue, J. A., Holtzman, G. I.

“…The Appalachian region in the eastern United Sates is home to the Earth's most extensive temperate deciduous forests, but coal mining has caused forest loss…”
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Toxoplasma‐induced hemophagocytic lymphohistiocytosis after haploidentical allogeneic stem cell transplantation by Sanchez‐Petitto, Gabriela, Holtzman, Noa G., Bukhari, Ali, Brown, Matthew, Morales, Megan K., Koka, Madhurima, Yared, Jean A., Dahiya, Saurabh, Rapoport, Aaron P., Hardy, Nancy M.

“…Hemophagocytic lymphohistiocytosis (HLH) is a disorder of immune regulation, manifested by fever, pancytopenia, hyperferritiniemia, hypertriglyceridemia, and…”
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Relapsed Philadelphia Chromosome-Positive Pre-B-ALL after CD19-Directed CAR-T Cell Therapy Successfully Treated with Combination of Blinatumomab and Ponatinib by El Chaer, Firas, Holtzman, Noa G, Sausville, Edward A, Law, Jennie Y, Lee, Seung Tae, Duong, Vu H, Baer, Maria R, Koka, Rima, Singh, Zeba N, Hardy, Nancy M, Emadi, Ashkan

“…Adults with relapsed or refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL) treated with conventional chemotherapy have dismal outcomes. Novel…”
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Hematopoietic Cell Transplantation in the Treatment of Newly Diagnosed Adult Acute Myeloid Leukemia: An Evidence-Based Review from the American Society of Transplantation and Cellular Therapy by Dholaria, Bhagirathbhai, Savani, Bipin N., Hamilton, Betty K., Oran, Betul, Liu, Hien D., Tallman, Martin S., Ciurea, Stefan Octavian, Holtzman, Noa G., II, Gordon L. Phillips, Devine, Steven M., Mannis, Gabriel, Grunwald, Michael R., Appelbaum, Frederick, Rodriguez, Cesar, El Chaer, Firas, Shah, Nina, Hashmi, Shahrukh K., Kharfan-Dabaja, Mohamed A., DeFilipp, Zachariah, Aljurf, Mahmoud, AlShaibani, AlFadel, Inamoto, Yoshihiro, Jain, Tania, Majhail, Navneet, Perales, Miguel-Angel, Mohty, Mohamad, Hamadani, Mehdi, Carpenter, Paul A., Nagler, Arnon

“…The role of hematopoietic cell transplantation (HCT) in the management of newly diagnosed adult acute myeloid leukemia (AML) is reviewed and critically…”
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FLT3 -ITD Allelic Burden and Acute Promyelocytic Leukemia Risk Stratification by Li, Andrew Y, Kashanian, Sarah M, Hambley, Bryan C, Zacholski, Kyle, Duong, Vu H, El Chaer, Firas, Holtzman, Noa G, Gojo, Ivana, Webster, Jonathan A, Norsworthy, Kelly J, Smith, Bruce Douglas, DeZern, Amy E, Levis, Mark J, Baer, Maria R, Kamangar, Farin, Ghiaur, Gabriel, Emadi, Ashkan

“…The significance of -ITD in acute promyelocytic leukemia (APL) is not well-established. We performed a bi-center retrospective study of 138 APL patients, 59…”
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Reverse Pseudohyperkalemia: An Important Clinical Entity in Chronic Lymphocytic Leukemia by Mansoor, Sahar, Emadi, Ashkan, Holtzman, Noa G.

“…Hyperkalemia is a potentially lethal electrolyte derangement commonly seen in patients with hematologic neoplasms with or without renal failure…”
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PCB and TCDD derived embryonic cardiac defects result from a novel AhR pathway by Singleman, Corinna, Holtzman, Nathalia G.

“…[Display omitted] •PCBs and TCDD disrupts heart development by reducing endocardial integrity.•They activate the AhR pathway causing phosphorylation of a…”
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Immunopathogenic mechanisms and modulatory approaches to graft-versus-host disease prevention in acute myeloid leukaemia by Pang, Yifan, Holtzman, Noa G.

“…Allogeneic haematopoietic stem cell transplantation (HSCT) remains the only potential cure for intermediate to high-risk acute myeloid leukaemia (AML). The…”
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W“H-Y” antigen/HLA complexes in chronic GVHD by Holtzman, Noa G., Pavletic, Steven Z.

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Increased body mass index is a risk factor for acute promyelocytic leukemia by Kashanian, Sarah M., Li, Andrew Y., Ali, Moaath Mustafa, Sutherland, Mark E., Duong, Vu H., Hambley, Bryan C., Zacholski, Kyle, El Chaer, Firas, Holtzman, Noa G., Imran, Mohammad, Patzke, Ciera L., Cornu, Jonathan, Duffy, Alison, Dezern, Amy E., Gojo, Ivana, Norsworthy, Kelly J., Levis, Mark J., Smith, B. Douglas, Baer, Maria R., Ghiaur, Gabriel, Emadi, Ashkan

“…Introduction Obesity has become increasingly prevalent worldwide and is a risk factor for many malignancies. We studied the correlation between body mass index…”
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