Search Results - "Holtkamp, C A"

Stakeholder perspectives on the implementation of genetic carrier screening in a changing landscape by Holtkamp, Kim C A, Vos, Evelien M, Rigter, Tessel, Lakeman, Phillis, Henneman, Lidewij, Cornel, Martina C

“…In most countries, genetic carrier screening is neither offered, nor embedded in mainstream healthcare. Technological developments have triggered a two-fold…”
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Preconception carrier screening for multiple disorders: evaluation of a screening offer in a Dutch founder population by Mathijssen, Inge B, Holtkamp, Kim C A, Ottenheim, Cecile P E, van Eeten-Nijman, Janneke M C, Lakeman, Phillis, Meijers-Heijboer, Hanne, van Maarle, Merel C, Henneman, Lidewij

“…Technological developments have enabled carrier screening for multiple disorders. This study evaluated experiences with a preconception carrier screening offer…”
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Attitudes of pregnant women and male partners towards non-invasive prenatal testing and widening the scope of prenatal screening by van Schendel, Rachèl V, Kleinveld, Johanna H, Dondorp, Wybo J, Pajkrt, Eva, Timmermans, Danielle R M, Holtkamp, Kim C A, Karsten, Margreet, Vlietstra, Anne L, Lachmeijer, Augusta M A, Henneman, Lidewij

“…Non-invasive prenatal testing (NIPT) and its potential to test for multiple disorders has received much attention. This study explores attitudes of women and…”
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Factors for successful implementation of population-based expanded carrier screening: learning from existing initiatives by Holtkamp, Kim C A, Mathijssen, Inge B, Lakeman, Phillis, van Maarle, Merel C, Dondorp, Wybo J, Henneman, Lidewij, Cornel, Martina C

“…Carrier screening for autosomal recessive disorders aims to facilitate reproductive decision-making by identifying couples with a 1-in-4 risk in every…”
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Do people from the Jewish community prefer ancestry-based or pan-ethnic expanded carrier screening? by Holtkamp, Kim C A, van Maarle, Merel C, Schouten, Maria J E, Dondorp, Wybo J, Lakeman, Phillis, Henneman, Lidewij

“…Ancestry-based carrier screening in the Ashkenazi Jewish population entails screening for specific autosomal recessive founder mutations, which are rarer among…”
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Direct-to-consumer carrier screening for cystic fibrosis via a hospital website: a 6-year evaluation by Holtkamp, Kim C. A., Henneman, Lidewij, Gille, Johan J. P., Meijers-Heijboer, Hanne, Cornel, Martina C., Lakeman, Phillis

“…A Dutch university hospital started offering cystic fibrosis (CF) carrier screening directly to consumers (DTC) through their website in 2010. A 6-year process…”
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Experiences of a High-Risk Population with Prenatal Hemoglobinopathy Carrier Screening in a Primary Care Setting: a Qualitative Study by Holtkamp, Kim C. A., Lakeman, Phillis, Hader, Hind, Jans, Suze M. J. P., Hoenderdos, Maria, Playfair, Henna A. M., Cornel, Martina C., Peters, Marjolein, Henneman, Lidewij

“…Carrier screening for hemoglobinopathies (HbPs; sickle cell disease and thalassemia) aims to facilitate autonomous reproductive decision-making. In the absence…”
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A comparative study of variables affecting the bleeding time using two disposable devices by Buchanan, G R, Holtkamp, C A

“…A number of variables affect the result of the bleeding time, the most frequently used test assessing primary hemostasis. Although the test is now usually…”
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Reduced hemoglobin values in children and young adults with hemophilia by BUCHANAN, G. R, HOLTKAMP, C. A

“…Mild leukopenia and thrombocytopenia are common in multitransfused hemophiliacs. Because little attention has previously been directed to measurements of…”
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Reduced serum haptoglobin values in hemophiliacs receiving monoclonally purified factor VIII concentrates by Buchanan, G R, Holtkamp, C A, Johnson, A

“…Hemophiliacs often have mild anemia, and hemolysis has been suggested as the likely mechanism on the basis of the reduced serum haptoglobin values frequently…”
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Pocked erythrocyte counts in patients with hereditary spherocytosis before and after splenectomy by Buchanan, G R, Holtkamp, C A

“…The pocked (pitted or vacuolated) erythrocyte count has become increasingly utilized as a simple inexpensive test of splenic reticuloendothelial function…”
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Severe hemorrhage in a patient with gray platelet syndrome by Gootenberg, J E, Buchanan, G R, Holtkamp, C A, Casey, C S

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Splenic reticuloendothelial function in children with cancer by Buchanan, G R, Holtkamp, C A

“…We studied splenic function in children with cancer by quantitation of pitted, or pocked, erythrocytes (pocked RBC count), that is, the percentage of…”
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Plasma levels of platelet and vascular prostaglandin derivatives in children with sickle cell anaemia by Buchanan, G R, Holtkamp, C A

“…Platelet and vascular endothelial prostaglandin derivatives were measured by radioimmunoassay in the plasma of 39 children with homozygous sickle cell anaemia…”
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Formation and disappearance of pocked erythrocytes: studies in human subjects and laboratory animals by Buchanan, G R, Holtkamp, C A, Horton, J A

“…The pocked or "pitted" RBC count is being increasingly utilized as a test of splenic function. Since little is known about patterns of formation and removal of…”
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Prolonged bleeding time in children and young adults with hemophilia by Buchanan, G R, Holtkamp, C A

“…Of 49 patients with hemophilia A or B, who had not received replacement transfusions for at least 72 hours, ten were demonstrated to have a prolonged value for…”
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Hepatitis in household contacts of patients with hemophilia who have received multiple transfusions by Buchanan, G R, Richards, N, Holtkamp, C A, Rutledge, J

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Bacterial infection and splenic reticuloendothelial function in children with hemoglobin SC disease by Buchanan, G R, Smith, S J, Holtkamp, C A, Fuseler, J P

“…Although the epidemiology and pathophysiology of serious bacterial infection in homozygous sickle cell anemia (SS disease) have become increasingly well…”
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Platelet aggregation, malondialdehyde generation and production time in children with sickle cell anaemia by Buchanan, G R, Holtkamp, C A

“…In view of prior reports of platelet activation in the sickling disorders, platelet aggregation, malondialdehyde (MDA) production following stimulation with…”
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Platelet number and function in Diamond-Blackfan anemia by Buchanan, G R, Alter, B P, Holtkamp, C A, Walsh, E G

“…Congenital red cell aplasia (Diamond-Blackfan anemia) is occasionally associated with hematologic defects other than a deficiency of red blood cell…”
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