Search Results - "Holterman, Ai Xuan Le"
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Optimization of the isolation procedure and culturing conditions for hepatic stellate cells obtained from mouse
Published in Bioscience reports (29-01-2021)“…Liver fibrosis (LF) mortality rate is approximately 2 million per year. Irrespective of the etiology of LF, a key element in its development is the transition…”
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Granulocyte colony-stimulating factor reduces biliary fibrosis and ductular reaction in a mouse model of chronic cholestasis
Published in Liver research (01-03-2023)“…Biliary atresia is a rare congenital bile duct disease that is the leading cause of liver fibrosis in neonates. Granulocyte colony-stimulating factor (GCSF) is…”
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Autophagy Inhibitor Chloroquine Downmodulates Hepatic Stellate Cell Activation and Liver Damage in Bile-Duct-Ligated Mice
Published in Cells (Basel, Switzerland) (27-03-2023)“…Hepatic stellate cell (HSC) activation via the autophagy pathway is a critical factor in liver fibrogenesis. This study tests the hypothesis that chloroquine…”
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Pediatric Obesity
Published in The Surgical clinics of North America (01-06-2012)“…Childhood obesity is a tremendous burden for children, their families, and society. Obesity prevention remains the ultimate goal but rapid development and…”
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Initial Experience With the Adjustable Gastric Band in Morbidly Obese US Adolescents and Recommendations for Further Investigation
Published in Journal of pediatric gastroenterology and nutrition (01-08-2007)“…ABSTRACT Background: The public health crisis of obesity has spread to the pediatric population. In morbidly obese (MO) adolescents, early weight loss…”
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Effects of autophagy inhibition by chloroquine on hepatic stellate cell activation in CCl4‐induced acute liver injury mouse model
Published in Journal of gastroenterology and hepatology (01-01-2022)“…Background and Aim Hepatic stellate cells (HSCs) activation, a critical event in liver fibrosis, has been recently shown to be related to autophagy. Determine…”
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Global Surgery: Effective Involvement of US Academic Surgery: Report of the American Surgical Association Working Group on Global Surgery
Published in Annals of surgery (01-10-2018)“…There is an unacceptably high burden of death and disability from conditions that are treatable by surgery, worldwide and especially in low- and middle-income…”
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Recombinant human granulocyte colony-stimulating factor alleviates liver fibrosis in bile duct-ligated mice
Published in Biomedical research and therapy (30-06-2019)“…Introduction: Biliary atresia (BA) is the leading cause of liver fibrosis and failure in neonates with surgical jaundice, leading to poor outcome. Clinical and…”
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