Search Results - "Holt, Andrew W."

FoxO3 normalizes Smad3-induced arterial smooth muscle cell growth by Francisco, Jake T, Holt, Andrew W, Bullock, Michael T, Williams, Madison D, Poovey, Cere E, Holland, Nathan A, Brault, Jeffrey J, Tulis, David A

“…Transition of arterial smooth muscle (ASM) from a quiescent, contractile state to a growth-promoting state is a hallmark of cardiovascular disease (CVD), a…”
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Soluble guanylyl cyclase-activated cyclic GMP-dependent protein kinase inhibits arterial smooth muscle cell migration independent of VASP-serine 239 phosphorylation by Holt, Andrew W., Martin, Danielle N., Shaver, Patti R., Adderley, Shaquria P., Stone, Joshua D., Joshi, Chintamani N., Francisco, Jake T., Lust, Robert M., Weidner, Douglas A., Shewchuk, Brian M., Tulis, David A.

“…Coronary artery disease (CAD) accounts for over half of all cardiovascular disease-related deaths. Uncontrolled arterial smooth muscle (ASM) cell migration is…”
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Inadvertent sodium loading in critically ill patients by Bihari, Shailesh, Ou, Judy, Holt, Andrew W, Bersten, Andrew D

“…Background: Recommended daily intake of sodium is 1- 2mmol/kg. Sodium administration is rarely separated from fluid administration in critically ill patients…”
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Traumatic Optic Nerve Injury Elevates Plasma Biomarkers of Traumatic Brain Injury in a Porcine Model by Bramblett, Gregory T, Harris, Jason N, Scott, Laura L, Holt, Andrew W

“…A diagnosis of traumatic brain injury (TBI) is typically based on patient medical history, a clinical examination, and imaging tests. Elevated plasma levels of…”
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Human platelet lysate delivered via an ocular wound chamber for the treatment of corneal epithelial injuries by Griffith, Gina L., Holt, Andrew W., Eriksson, Elof, Johnson, Anthony J., McDaniel, Jennifer S.

“…Current strategies to address corneal surface defects are insufficient to successfully resolve damage caused by injury and/or disease. To address this issue,…”
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Addition of indapamide to frusemide increases natriuresis and creatinine clearance, but not diuresis, in fluid overloaded ICU patients by Bihari, Shailesh, Holt, Andrew W, Prakash, Shivesh, Bersten, Andrew D

“…Abstract Background Fluid and sodium overload are a common problem in critically ill patients. Frusemide may result in diuresis in excess of natriuresis. The…”
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AMP-activated protein kinase inhibits transforming growth factor-β-mediated vascular smooth muscle cell growth: implications for a Smad-3-dependent mechanism by Stone, Joshua D, Holt, Andrew W, Vuncannon, Jackson R, Brault, Jeffrey J, Tulis, David A

“…Dysfunctional vascular growth is a major contributor to cardiovascular disease, the leading cause of morbidity and mortality worldwide. Growth factor-induced…”
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Use of an ocular wound chamber for the prevention of exposure keratopathy in a guinea pig model by Holt, Andrew W, McDaniel, Jennifer S, Bramblett, Gregory T, Eriksson, Elof, Johnson, Anthony J, Griffith, Gina L

“…Current therapies available to treat and heal ocular surface injuries and periocular burns are frequently inadequate, costly, and labor intensive. To address…”
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BDNF and cAMP are neuroprotective in a porcine model of traumatic optic neuropathy by Heng, Kathleen, Young, Brent K, Li, BaoXiang, Nies, Ashley D, Xia, Xin, Wen, Runxia R, Dalal, Roopa, Bramblett, Gregory T, Holt, Andrew W, Cleland, Jeffery M, Harris, Jason N, Wu, Albert Y, Goldberg, Jeffrey L

“…Traumatic optic neuropathy (TON) is a devastating condition that can occur after blunt or penetrating trauma to the head, leading to visual impairment or…”
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Issues for clinicians training international medical graduates by Holt, Andrew W

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The utilization of an ocular wound chamber on corneal epithelial wounds by McDaniel, Jennifer S, Holt, Andrew W, Por, Elaine D, Eriksson, Elof, Johnson, Anthony J, Griffith, Gina L

“…Currently available ocular moisture chambers are not adequate to manage the treatment of periocular burns, corneal injuries, and infection. The purpose of…”
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Making the cut: Innovative methods for optimizing perfusion‐based migration assays by Holt, Andrew W., Howard, William E., Ables, Elizabeth T., George, Stephanie M., Kukoly, Cindy A., Rabidou, Jake E., Francisco, Jake T., Chukwu, Angel N., Tulis, David A.

“…Application of fluid shear stress to adherent cells dramatically influences their cytoskeletal makeup and differentially regulates their migratory phenotype…”
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Healthcare costs and outcomes for patients undergoing tracheostomy in an Australian tertiary level referral hospital by Bihari, Shailesh, Prakash, Shivesh, Hakendorf, Paul, Horwood, Christopher MacBryde, Tarasenko, Steve, Holt, Andrew W, Ratcliffe, Julie, Bersten, Andrew D

“…Objective Patients undergoing tracheostomy represent a unique cohort, as often they have prolonged hospital stay, require multi-disciplinary,…”
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The role of estrogen in the developmental appearance of sensory-motor behaviors in the zebrafish ( Danio rerio ): The characterization of the “listless” model by Nelson, Bryan P, Henriet, Russ P, Holt, Andrew W, Bopp, Katherine C, Houser, Alexander P, Allgood, Ottie E, Turner, James E

“…Abstract The brain is a steroidogenic organ and is thus dependent on estrogen for many aspects of its development and maintenance in both males and females…”
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Do advance care directives improve acute care services for older people? by Holt, Andrew W, Vedig, Alnis E

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Treatment of Severe Cardiogenic Pulmonary Edema with Continuous Positive Airway Pressure Delivered by Face Mask by Bersten, Andrew D, Holt, Andrew W, Vedig, Alnis E, Skowronski, George A, Baggoley, Christopher J

“…CARDIOGENIC pulmonary edema is a common clinical problem in most hospitals. Despite the use of supplemental oxygen and the administration of drugs to decrease…”
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Conventional coagulation and thromboelastograph parameters and longevity of continuous renal replacement circuits by HOLT, Andrew W, BIERER, Petra, GLOVER, Paul, PLUMMER, John L, BERSTEN, Andrew D

“…To determine the relationship between conventional and thromboelastograph (TEG) coagulation parameters and continuous renal replacement therapy (CRRT) circuit…”
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Matricryptin p1158/59 Modulates Vascular Remodeling During Carotid Artery Bypass by Shaver, Patti R, Grilo, Gabriel A, Barefoot, Katherine C, Holt, Andrew W, Tulis, David A, Lust, Robert M, de Castro Brás, Lisandra E.

“…Abstract only When atherosclerosis develops in the coronary arteries, blood flow is compromised and disease progression increases the risk of myocardial…”
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Prospective evaluation of residents and nurses as severity score data collectors by Holt, A W, Bury, L K, Bersten, A D, Skowronski, G A, Vedig, A E

“…To determine the interobserver reliability of residents and nurses collecting Acute Physiology and Chronic Health Evaluation (APACHE II) data and the…”
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Hemodynamic responses to amiodarone in critically ill patients receiving catecholamine infusions by Holt, A W

“…The hemodynamic response after an iv loading dose of amiodarone for resistant supraventricular tachyarrhythmias was studied in ten critically ill patients…”
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