Search Results - "Holstein, A."

Daratumumab, lenalidomide, bortezomib, and dexamethasone for transplant-eligible newly diagnosed multiple myeloma: the GRIFFIN trial by Voorhees, Peter M., Kaufman, Jonathan L., Laubach, Jacob, Sborov, Douglas W., Reeves, Brandi, Rodriguez, Cesar, Chari, Ajai, Silbermann, Rebecca, Costa, Luciano J., Anderson, Larry D., Nathwani, Nitya, Shah, Nina, Efebera, Yvonne A., Holstein, Sarah A., Costello, Caitlin, Jakubowiak, Andrzej, Wildes, Tanya M., Orlowski, Robert Z., Shain, Kenneth H., Cowan, Andrew J., Murphy, Sean, Lutska, Yana, Pei, Huiling, Ukropec, Jon, Vermeulen, Jessica, de Boer, Carla, Hoehn, Daniela, Lin, Thomas S., Richardson, Paul G.

“…Lenalidomide, bortezomib, and dexamethasone (RVd) followed by autologous stem cell transplantation (ASCT) is standard frontline therapy for transplant-eligible…”
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Lenalidomide Maintenance After Autologous Stem-Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Meta-Analysis by McCarthy, Philip L, Holstein, Sarah A, Petrucci, Maria Teresa, Richardson, Paul G, Hulin, Cyrille, Tosi, Patrizia, Bringhen, Sara, Musto, Pellegrino, Anderson, Kenneth C, Caillot, Denis, Gay, Francesca, Moreau, Philippe, Marit, Gerald, Jung, Sin-Ho, Yu, Zhinuan, Winograd, Benjamin, Knight, Robert D, Palumbo, Antonio, Attal, Michel

“…Purpose Lenalidomide maintenance therapy after autologous stem-cell transplantation (ASCT) demonstrated prolonged progression-free survival (PFS) versus…”
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Targeting the Isoprenoid Biosynthetic Pathway in Multiple Myeloma by Haney, Staci L, Holstein, Sarah A

“…Multiple myeloma (MM) is a plasma cell malignancy for which there is currently no cure. While treatment options for MM have expanded over the last two decades,…”
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International harmonization in performing and reporting minimal residual disease assessment in multiple myeloma trials by Costa, Luciano J., Derman, Benjamin A., Bal, Susan, Sidana, Surbhi, Chhabra, Saurabh, Silbermann, Rebecca, Ye, Jing C., Cook, Gordon, Cornell, Robert F., Holstein, Sarah A., Shi, Qian, Omel, James, Callander, Natalie S., Chng, Wee Joo, Hungria, Vania, Maiolino, Angelo, Stadtmauer, Edward, Giralt, Sergio, Pasquini, Marcelo, Jakubowiak, Andrzej J., Morgan, Gareth J., Krishnan, Amrita, Jackson, Graham H., Mohty, Mohamad, Mateos, Maria Victoria, Dimopoulos, Meletious A., Facon, Thierry, Spencer, Andrew, Miguel, Jesus San, Hari, Parameswaran, Usmani, Saad Z., Manier, Salomon, McCarthy, Phillip, Kumar, Shaji, Gay, Francesca, Paiva, Bruno

“…Minimal residual disease (MRD) assessment is incorporated in an increasing number of multiple myeloma (MM) clinical trials as a correlative analysis, an…”
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Contraindications can damage your health--is metformin a case in point by Holstein, A, Stumvoll, M

“…Metformin is an effective anti-hyperglycaemic and cardioprotective agent, but a long list of contraindications precludes millions of patients with type 2…”
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A process‐based approach to hominin taxonomy provides new perspectives on hominin speciation by Holstein, Laura A., Foley, Robert A.

“…A longstanding debate in hominin taxonomy is that between “lumpers” and “splitters.” We argue that both approaches assume an unrealistically static model of…”
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Gastrointestinal: Whipple's disease: Often taught but rarely seen and diagnosed late by Holstein, A, Michels, C, Bryson, R W, Schulz, B

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Immobilizing affinity proteins to nitrocellulose: a toolbox for paper-based assay developers by Holstein, Carly A., Chevalier, Aaron, Bennett, Steven, Anderson, Caitlin E., Keniston, Karen, Olsen, Cathryn, Li, Bing, Bales, Brian, Moore, David R., Fu, Elain, Baker, David, Yager, Paul

“…To enable enhanced paper-based diagnostics with improved detection capabilities, new methods are needed to immobilize affinity reagents to porous substrates,…”
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Geranylgeranyl diphosphate synthase: Role in human health, disease and potential therapeutic target by Muehlebach, Molly E., Holstein, Sarah A.

“…Geranylgeranyl diphosphate synthase (GGDPS), an enzyme in the isoprenoid biosynthesis pathway, is responsible for the production of geranylgeranyl…”
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The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1 by O'Leary, Monique N, Schreiber, Katherine H, Zhang, Yong, Duc, Anne-Cécile E, Rao, Shuyun, Hale, J Scott, Academia, Emmeline C, Shah, Shreya R, Morton, John F, Holstein, Carly A, Martin, Dan B, Kaeberlein, Matt, Ladiges, Warren C, Fink, Pamela J, Mackay, Vivian L, Wiest, David L, Kennedy, Brian K

“…Most yeast ribosomal protein genes are duplicated and their characterization has led to hypotheses regarding the existence of specialized ribosomes with…”
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Development and Validation of an LC-MS/MS Assay for the Quantitation of MO-OH-Nap Tropolone in Mouse Plasma: Application to In Vitro and In Vivo Pharmacokinetic Studies by Aldhafiri, Wafaa N, Chhonker, Yashpal S, Ahmed, Nusrat, Singh, Sandeep K, Haney, Staci L, Ford, James B, Holstein, Sarah A, Murry, Daryl J

“…A rapid, selective, and sensitive liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) method was developed and validated for the…”
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Treatment Considerations for Transplant-Ineligible Multiple Myeloma by Elnair, Radowan, Holstein, Sarah

“…While significant advances have been made in the treatment of multiple myeloma, the management of the transplant-ineligible (TI) patient population remains…”
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Downstream bioprocessing: recent advances and future promise by Cramer, Steven M, Holstein, Melissa A

“…► Increased titers, product quality constraints, and regulatory directives have driven advances in downstream bioprocessing. ► Improvements in traditional…”
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The role of osteocytes in targeted bone remodeling: a mathematical model by Graham, Jason M, Ayati, Bruce P, Holstein, Sarah A, Martin, James A

“…Until recently many studies of bone remodeling at the cellular level have focused on the behavior of mature osteoblasts and osteoclasts, and their respective…”
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Simultaneous Quantitation of Isoprenoid Pyrophosphates in Plasma and Cancer Cells Using LC-MS/MS by Chhonker, Yashpal S, Haney, Staci L, Bala, Veenu, Holstein, Sarah A, Murry, Daryl J

“…Isoprenoids (IsoP) are an important class of molecules involved in many different cellular processes including cholesterol synthesis. We have developed a…”
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Multidimensional primate niche space sheds light on interspecific competition in primate evolution by van Holstein, L. A., McKay, H. D., Pimiento, C., Koops, K.

“…Characterising how the totality of primate diversity is distributed across the order, and how it evolved, is challenging because diversity in individual traits…”
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Publisher Correction: Multidimensional primate niche space sheds light on interspecific competition in primate evolution by van Holstein, L. A., McKay, H. D., Pimiento, C., Koops, K.

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Recent Advances in the Development of Mammalian Geranylgeranyl Diphosphate Synthase Inhibitors by Haney, Staci L, Wills, Veronica S, Wiemer, David F, Holstein, Sarah A

“…The enzyme geranylgeranyl diphosphate synthase (GGDPS) catalyzes the synthesis of the 20-carbon isoprenoid geranylgeranyl diphosphate (GGPP). GGPP is the…”
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Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site by Strauch, Eva-Maria, Bernard, Steffen M, La, David, Bohn, Alan J, Lee, Peter S, Anderson, Caitlin E, Nieusma, Travis, Holstein, Carly A, Garcia, Natalie K, Hooper, Kathryn A, Ravichandran, Rashmi, Nelson, Jorgen W, Sheffler, William, Bloom, Jesse D, Lee, Kelly K, Ward, Andrew B, Yager, Paul, Fuller, Deborah H, Wilson, Ian A, Baker, David

“…A method to target trimeric membrane proteins by designing geometrically matched trimeric protein binders is demonstrated for the influenza-virus glycoprotein…”
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Evaluation of protein adsorption and preferred binding regions in multimodal chromatography using NMR by Chung, Wai Keen, Freed, Alexander S., Holstein, Melissa A., McCallum, Scott A., Cramer, Steven M.

“…NMR titration experiments with labeled human ubiquitin were employed in concert with chromatographic data obtained with a library of ubiquitin mutants to study…”
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