Search Results - "Holson, J.F."

Developmental toxicity in rats of a hemoglobin-based oxygen carrier results from impeded function of the inverted visceral yolk sac by Stump, D.G., Holson, J.F., Harris, C., Pearce, L.B., Watson, R.E., DeSesso, J.M.

“…•Infusion HBOC into pregnant rats causes developmental toxicity.•Sensitive from GD 7 to 11 when inverted yolk sac placenta (invYSP) supplies…”
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Evaluation of the prenatal developmental toxicity of orally administered arsenic trioxide in rats by Holson, J.F, Stump, D.G, Clevidence, K.J, Knapp, J.F, Farr, C.H

“…A thorough review of the literature revealed no published repeated-dose oral developmental toxicity studies of inorganic arsenic in rats. In the present study,…”
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Absence of developmental toxicity in a canine model after infusion of a hemoglobin-based oxygen carrier: Implications for risk assessment by Holson, J.F., Stump, D.G., Pearce, L.B., Watson, R.E., DeSesso, J.M.

“…•HBOC infused into pregnant rats interferes with invYSP function.•HBOC interference with invYSP function causes developmental toxicity in rats.•Infusion of…”
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Developmental toxicity of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). I. Multireplicated dose-response studies in four inbred strains and one outbred stock of mice by Holson, J F, Gaines, T B, Nelson, C J, LaBorde, J B, Gaylor, D W, Sheehan, D M, Young, J F

“…A large-scaled multireplicated developmental toxicity study was conducted in various strains/stocks of mice with the herbicide, 2,4,5-trichlorophenoxyacetic…”
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Reproductive toxicity studies with octamethylcyclotetrasiloxane in female rats using various exposure regimens by Reynolds, V.L., DeSesso, J.M., Mast, R.W., Stump, D.G., Holson, J.F.

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Developmental toxicity of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). II. Multireplicated dose-response studies with technical and analytical grades of 2,4,5-T in four-way outcross mice by Nelson, C J, Holson, J F, Gaines, T B, LaBorde, J B, McCallum, W F, Wolff, G L, Sheehan, D M, Young, J F

“…A series of multireplicated developmental toxicity studies were conducted in four-way outcross mice and CD-1 outbred mice administered either analytical or…”
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Retrospective study of the relationship between agricultural use of 2,4,5-T and cleft palate occurrence in Arkansas by Nelson, C J, Holson, J F, Green, H G, Gaylor, D W

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Comparative effects of single intraperitoneal or oral doses of sodium arsenate or arsenic trioxide during in utero development by Stump, D.G., Holson, J.F., Fleeman, T.L., Nemec, M.D., Farr, C.H.

“…Numerous studies have suggested that single‐day intraperitoneal (IP) injection of inorganic arsenic results in failure of neural tube closure and other…”
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Altered pattern of prenatal toxicity in rats due to different treatment schedules with mirex by Byrd, R A, Kimmel, C A, Morris, M D, Holson, J F, Young, J F

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Computer simulation of mirex pharmacokinetics in the rat by Byrd, R A, Young, J F, Kimmel, C A, Morris, M D, Holson, J F

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Subchronic, Developmental, and Genetic Toxicology Studies with the Ethane Sulfonate Metabolite of Alachlor by Heydens, William F., Siglin, Joseph C., Holson, Joseph F., Stegeman, Sheila D.

“…The ethane sulfonate (ESA) metabolite of the herbicide alachlor is formed in soil by microbial action. The present studies were conducted to assess the…”
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Teratological evaluation of FD&C Red no. 2-a collaborative government -industry study. V. Combined findings and discussion by Holson, Jr, J F, Gaylor, D W, Schumacher, H J, Collins, T F, Ruggles, D I, Keplinger, M L, Kennedy, Jr, G L

“…Because of recent studies indicating possible embryolethality and teratogenicity of FD&C Red No. 2, anad hoc committee was convened by the Food and Drug…”
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Small animal traversing gamma counter by McVey, J T, Hunziker, J, Holson, J F, Young, J F

“…A whole body traverser was developed that provides a variety of radionuclide detection configurations for retention and distribution studies. Data from…”
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