Search Results - "Holmuhamedov, E."

Effect of ONC201 Antitumor Drug on the Number of Mitochondrial Nucleoids in BT474 Breast Cancer Cells in Culture by Mishukov, A. A., Berezhnov, A. V., Kobyakova, M. I., Evstratova, Ya. V., Mndlyan, E. Yu, Holmuhamedov, E. L.

“…The effect of the cytostatic antitumor drug ONC201 on the number of mitochondrial nucleoids and the average size of mitochondria in the BT474 human breast…”
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Fibronectin is a survival factor for differentiated osteoblasts by Globus, R. K., Doty, S. B., Lull, J. C., Holmuhamedov, E., Humphries, M. J., Damsky, C. H.

“…The skeletal extracellular matrix produced by osteoblasts contains the glycoprotein fibronectin, which regulates the adhesion, differentiation and function of…”
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Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes by Jouaville, Laurence S, Ichas, François, Holmuhamedov, Ekhson L, Camacho, Patricia, Lechleiter, James D

“…In Xenopus oocytes, as well as other cells, inositol-1,4,5-trisphosphate (Ins(1,4,5)P3)-induced Ca2+ release is an excitable process that generates propagating…”
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Adaphostin and other anticancer drugs quench the fluorescence of mitochondrial potential probes by Le, S B, Holmuhamedov, E L, Narayanan, V L, Sausville, E A, Kaufmann, S H

“…Fluorescent dyes are widely used to monitor changes in mitochondrial transmembrane potential (DeltaPsim). When MitoTracker Red CMXRos, tetramethylrhodamine…”
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Establishment of an orthotopic tumor model in the mammary gland of BALB/C nude mice using human breast cancer MCF-7 cells and their VDAC-deficient derivatives by Mndlyan, E. Yu, Semushina, S. G., Rzhevsky, D. I., Novikova, N. I., Kalabina, E. A., Komkov, D. S., Maslennikova, A. Yu, Murashev, A. N., Holmuhamedov, E. L.

“…Purpose to study the tumor-forming activity of wild-type MC F-7 cells carrying a full set of porins (VDAC 1, VDAC 2, VDAC 3), as well as their genetically…”
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Mitochondrial ATP-sensitive K+ channels modulate cardiac mitochondrial function by Holmuhamedov, E L, Jovanović, S, Dzeja, P P, Jovanović, A, Terzic, A

“…Discovered in the cardiac sarcolemma, ATP-sensitive K+ (KATP) channels have more recently also been identified within the inner mitochondrial membrane. Yet the…”
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Isoforms of voltage-dependent anion channel of the outer mitochondrial membrane and experimental models to study their physiological role by Teplova, V. V., Odinokova, I. V., Holmuhamedov, E. L.

“…The review outlines our current understanding of the role of porins, the proteins forming voltage-dependent anion channels (VDAC), in regulation of…”
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Role of phosphorylation of porin (VDAC) in regulation of mitochondrial outer membrane under normal conditions and alcohol intoxication by Azarashvili, T. S., Odinokova, I. V., Krestinina, O. V., Baburina, Y. L., Grachev, D. E., Teplova, V. V., Holmuhamedov, E. L.

“…The present work is an overview of the factors regulating permeability of the outer membrane of mitochondria and the state of the channels formed by porin…”
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Diazoxide protects mitochondria from anoxic injury: Implications for myopreservation by Ozcan, Cevher, Holmuhamedov, Ekhson L., Jahangir, Arshad, Terzic, Andre

“…Background: Heart muscle primarily relies on adenosine triphosphate produced by oxidative phosphorylation and is highly vulnerable to anoxic insult. Although a…”
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Human Endothelial Progenitor Cells Tolerate Oxidative Stress Due to Intrinsically High Expression of Manganese Superoxide Dismutase by He, Tongrong, Peterson, Timothy E, Holmuhamedov, Ekhson L, Terzic, Andre, Caplice, Noel M, Oberley, Larry W, Katusic, Zvonimir S

“…OBJECTIVE—Endothelial progenitor cells (EPCs) display a unique aptitude to promote angiogenesis and restore endothelial function of injured vessels. How…”
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Increased calcium vulnerability of senescent cardiac mitochondria: protective role for a mitochondrial potassium channel opener by Jahangir, Arshad, Ozcan, Cevher, Holmuhamedov, Ekhson L., Terzic, Andre

“…In senescence, endogenous mechanisms of cardioprotection are apparently attenuated resulting in increased vulnerability to ischemia-reperfusion. In particular,…”
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ATP-sensitive K+ channel openers prevent Ca2+ overload in rat cardiac mitochondria by Holmuhamedov, Ekhson L., Wang, Liewei, Terzic, Andre

“…Mitochondrial dysfunction, secondary to excessive accumulation of Ca 2+ , has been implicated in cardiac injury. We here examined the action of potassium…”
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Voltage-dependent anion channel (VDAC) as mitochondrial governator—Thinking outside the box by Lemasters, John J., Holmuhamedov, Ekhson

“…Despite a detailed understanding of their metabolism, mitochondria often behave anomalously. In particular, global suppression of mitochondrial metabolism and…”
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Mitochondria: Gateway for Cytoprotection by Dzeja, Petras P, Holmuhamedov, Ekshon L, Ozcan, Cevher, Pucar, Darko, Jahangir, Arshad, Terzic, Andre

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Restoration of Ca2+-inhibited oxidative phosphorylation in cardiac mitochondria by mitochondrial Ca2+ unloading by Holmuhamedov, E L, Ozcan, C, Jahangir, A, Terzic, A

“…Mitochondria, the major source of cellular ATP, display high vulnerability to metabolic stress, in particular to excessive Ca2+ loading. Here, we show that…”
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Mitochondrial calcium spiking: A transduction mechanism based on calcium-induced permeability transition involved in cell calcium signalling by Ichas, François, Jouaville, Laurence S., Sidash, Sergueï S., Mazat, Jean-Pierre, Holmuhamedov, Ekhson L.

“…We report reversible Ca 2+-induced Ca 2+ release from mitochondria, which takes the form of Ca 2+ spikes. Mitochondrial Ca 2+ spiking is an all-or-none process…”
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Non-cholinergic Toxicity of Organophosphates in Mammals: Interaction of Ethaphos with Mitochondrial Functions by Holmuhamedov, E. L., Kholmoukhamedova, G. L., Baimuradov, T. B.

“…The effect of the organophosphorus insecticide O‐ethyl‐S‐propyl‐2, 4‐dichlorophenylphosphorothioate (ethaphos) on mitochondrial functions was studied. It was…”
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Role of mitochondria in hepatotoxicity of ethanol by Teplova, V. V., Belosludtsev, K. N., Belosludtseva, N. V., Holmuhamedov, E. L.

“…The current understanding of the effects of alcohol intoxication on the basic mitochondrial functions has been presented. Both, the direct toxic effect of…”
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A study of the effect of ethanol on the synthesis of serine and the exchange of methyl groups in hepatocytes by NMR spectroscopy by Holmuhamedov, E. L., Teplova, V. V., Johnson, C. B., MacDonald, J.

“…The method of NMR spectroscopy was used to investigate the role of voltage-dependent anion channels in the outer mitochondrial membrane in the mechanism of…”
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Role of voltage-dependent anion channels of the mitochondrial outer membrane in regulation of cell metabolism by Holmuhamedov, E. L., Czerny, C., Lovelace, G., Beeson, C. C., Baker, T., Johnson, C. B., Pediaditakis, P., Teplova, V. V., Tikunov, A., MacDonald, J., Lemasters, J. J.

“…The role of voltage-dependent anion channels (VDAC/porins) of the mitochondrial outer membrane in the regulation of cell metabolism is assessed using an…”
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