Search Results - "Holmquist, G P"

Chromosome bands, their chromatin flavors, and their functional features by HOLMQUIST, G. P

“…To show that the input pattern of chromosomal mutations is highly organized relative to the band patterns along human chromosomes, a new term, "metaphase…”
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Role of replication time in the control of tissue-specific gene expression by HOLMQUIST, G. P

“…Late-replicating chromatin in vertebrates is repressed. Housekeeping (constitutively active) genes always replicate early and are in the early-replicating…”
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L1 repeat is a basic unit of heterochromatin satellites in cetaceans by Kapitonov, V V, Holmquist, G P, Jurka, J

“…Mammalian heterochromatin, pericentric, telomeric, or intercalary, is usually composed of long arrays of tandemly repeated DNA sequences called satellites,…”
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Cancerous hyper-mutagenesis in p53 genes is possibly associated with transcriptional bypass of DNA lesions by Rodin, S N, Rodin, A S, Juhasz, A, Holmquist, G P

“…The database of tumor-associated p53 base substitutions includes about 5% of tumors with two or more base substitutions. These multiplet base substitutions in…”
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Mapping frequencies of endogenous oxidative damage and the kinetic response to oxidative stress in a region of rat mtDNA by Driggers, W. J., Holmquist, G. P., LeDoux, S. P., Wilson, G. L.

“…Genomic DNA is constantly being damaged and repaired and our genomes exist at lesion equilibrium for damage created by endogenous mutagens. Mitochondrial DNA…”
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DNA Repair Rates Mapped Along the Human PGK1 Gene at Nucleotide Resolution by Gao, Shuwei, Drouin, Régen, Holmquist, Gerald P.

“…The repair of cyclobutane pyrimidine dimers (CPDs), DNA lesions induced by ultraviolet light, was studied at nucleotide resolution. Human fibroblasts were…”
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Binding of transcription factors creates hot spots for UV photoproducts in vivo by PFEIFER, G. P, DROUIN, R, RIGGS, A. D, HOLMQUIST, G. P

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Evidence for DNA Charge Transport in the Nucleus by Núñez, Megan E, Holmquist, Gerald P, Barton, Jacqueline K

“…Oxidative damage to DNA bases in isolated HeLa nuclei occurs upon treatment with rhodium intercalators and photoactivation. Oxidation occurs preferentially at…”
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Chromosome organization and chromatin modification: influence on genome function and evolution by Holmquist, G P, Ashley, T

“…Histone modifications of nucleosomes distinguish euchromatic from heterochromatic chromatin states, distinguish gene regulation in eukaryotes from that of…”
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In vivo Mapping of a DNA Adduct at Nucleotide Resolution: Detection of Pyrimidine (6-4) Pyrimidone Photoproducts by Ligation-Mediated Polymerase Chain Reaction by Pfeifer, Gerd P., Drouin, Regen, Riggs, Arthur D., Holmquist, Gerald P.

“…DNA adducts in unique sequences along the mammalian genome are mapped in vivo at single-nucleotide resolution. Pyrimidine (6-4) pyrimidone photoproducts [(6-4)…”
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Ligation-mediated PCR: robotic liquid handling for DNA damage and repair by Dai, S M, O'Connor, T R, Holmquist, G P, Riggs, A D, Flanagan, S D

“…The investigation of in vivo DNA repair in mammalian cells at nucleotide resolution requires the quantification of break frequencies less than one per…”
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Metal ion-dependent hydrogen peroxide-induced DNA damage is more sequence specific than metal specific by RODRIGUEZ, H, HOLMQUIST, G. P, D'AGOSTINO, R. JR, KELLER, J, AKMAN, S. A

“…The frequency of oxidative base damage along the human p53 and PGK1 genes was determined at nucleotide resolution by cleaving DNA at oxidized bases with…”
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Evolution of chromosome bands: molecular ecology of noncoding DNA by HOLMQUIST, G. P

“…Giemsa dark bands, G-bands, are a derived chromatin character that evolved along the chromosomes of early chordates. They are facultative heterochromatin…”
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Repair rates of R-band, G-band and C-band DNA in murine and human cultured cells by Sanders, M H, Bates, S E, Wilbur, B S, Holmquist, G P

“…Repair of cyclobutane pyrimidine dimers (CPDs) in cultured neonatal human fibroblasts and in Mus spretus x M. castaneus F1 neonatal skin fibroblasts was…”
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Replication Timing of Genes and Middle Repetitive Sequences by Goldman, Michael A., Holmquist, Gerald P., Gray, Martha C., Caston, Lucetta A., Nag, Abhijit

“…DNA replication in mammals is temporally bimodal. ``Housekeeping'' genes, which are active in all cells, replicate during the first half of the S phase of cell…”
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CpG transition strand asymmetry and hitch-hiking mutations as measures of tumorigenic selection in shaping the p53 mutation spectrum by Rodin, S N, Holmquist, G P, Rodin, A S

“…By the genetic code, the average protein perturbation expected from a CpG-->TpG transition is strand-specific and smallest when it originates with the C on the…”
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Mobile genetic elements, chiasmata, and the unique organization of beta-heterochromatin by Holmquist, G P, Kapitonov, V V, Jurka, J

“…Beta-heterochromatin in Drosophila and the Syrian hamster share a similar DNA organization, few unique sequences, and scrambled repeats of mobile elements…”
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Telomere Replication, Kinetochore Organizers, and Satellite DNA Evolution by Holmquist, Gerald P., Dancis, Barry

“…Robertsonian rearrangements demonstrate one-break chromosome rearrangement and the reversible appearance and disappearance of telomeres and centromeres. Such…”
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High-resolution replication bands compared with morphologic G- and R-bands by Drouin, R, Holmquist, G P, Richer, C L

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Heterogeneous repair of N-methylpurines at the nucleotide level in normal human cells by Ye, N, Holmquist, G P, O'Connor, T R

“…Base excision repair rates of dimethyl sulfate-induced 3-methyladenine and 7-methylguanine adducts were measured at nucleotide resolution along the PGK1 gene…”
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