Search Results - "Holmes, Scott A"

Sensorimotor Integration and Pain Perception: Mechanisms Integrating Nociceptive Processing. A Systematic Review and ALE-Meta Analysis by Gombaut, Cindy, Holmes, Scott A.

“…Pain treatment services and clinical indicators of pain chronicity focus on afferent nociceptive projections and psychological markers of pain perception with…”
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GABA and glutamate levels correlate with MTR and clinical disability: Insights from multiple sclerosis by Nantes, Julia C., Proulx, Sébastien, Zhong, Jidan, Holmes, Scott A., Narayanan, Sridar, Brown, Robert A., Hoge, Richard D., Koski, Lisa

“…Converging areas of research have implicated glutamate and γ-aminobutyric acid (GABA) as key players in neuronal signalling and other central functions…”
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Sex and age-related patterns in pediatric primary headaches: observations from an outpatient headache clinic by Faria, Vanda, Höfer, Berit, Klimova, Anna, von der Hagen, Maja, Berner, Reinhard, Sabatowski, Rainer, Koch, Thea, Hübler, Anke, Richter, Matthias, Moulton, Eric A, Holmes, Scott A, Gossrau, Gudrun

“…Age reportedly affects headache prevalence differently in boys and girls. However, little empirical data exists regarding pediatric headache prevalence and…”
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Intracortical inhibition abnormality during the remission phase of multiple sclerosis is related to upper limb dexterity and lesions by Nantes, Julia C, Zhong, Jidan, Holmes, Scott A, Whatley, Benjamin, Narayanan, Sridar, Lapierre, Yves, Arnold, Douglas L, Koski, Lisa

“…Highlights • Cortical silent period (CSP) prolongation is related to upper extremity impairment of people with relapsing-remitting multiple sclerosis (RRMS) in…”
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Combined structural and functional patterns discriminating upper limb motor disability in multiple sclerosis using multivariate approaches by Zhong, Jidan, Chen, David Qixiang, Nantes, Julia C., Holmes, Scott A., Hodaie, Mojgan, Koski, Lisa

“…A structural or functional pattern of neuroplasticity that could systematically discriminate between people with impaired and preserved motor performance could…”
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Delineating conditions and subtypes in chronic pain using neuroimaging by Holmes, Scott A., Upadhyay, Jaymin, Borsook, David

“…Abstract Differentiating subtypes of chronic pain still remains a challenge—both from a subjective and objective point of view. Personalized medicine is the…”
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Quantitative sensory testing in a magnetic resonance environment: considerations for thermal sensitivity and patient safety by Kim, Ayeong (Jenny), Szabo, Edina, Lunde, Claire E., Comptdaer, Gabriela, Zurakowski, David, Sieberg, Christine B., Holmes, Scott A.

“…Introduction Quantitative sensory testing (QST) is often used to understand the perceptual basis of acute and chronic conditions, including pain. As the need…”
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Evidence of Chronic Complement Activation in Asymptomatic Pediatric Brain Injury Patients: A Pilot Study by Holmes, Scott A, Mar'i, Joud, Lemme, Jordan, Maallo, Anne Margarette, Lebel, Alyssa, Simons, Laura, O'Brien, Michael J, Zurakowski, David, Burnstein, Rami, Borsook, David

“…Physical insult from a mild Traumatic Brain Injury (mTBI) leads to changes in blood flow in the brain and measurable changes in white matter, suggesting a…”
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Grasping time does not influence the early adherence of aperture shaping to Weber's law by Heath, Matthew, Holmes, Scott A, Mulla, Ali, Binsted, Gordon

“…The "just noticeable difference" (JND) represents the minimum amount by which a stimulus must change to produce a noticeable variation in one's perceptual…”
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DTI and MTR Measures of Nerve Fiber Integrity in Pediatric Patients With Ankle Injury by Holmes, Scott A, Karapanagou, Anastasia, Staffa, Steven J, Zurakowski, David, Borra, Ronald, Simons, Laura E, Sieberg, Christine, Lebel, Alyssa, Borsook, David

“…Acute peripheral nerve injury can lead to chronic neuropathic pain. Having a standardized, non-invasive method to evaluate pathological changes in a nerve…”
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Goal-directed grasping: The dimensional properties of an object influence the nature of the visual information mediating aperture shaping by Holmes, Scott A., Heath, Matthew

“…► Behavioral and neuroimaging studies of grasping have used 2D objects as a proxy for 3D objects. ► We examined whether the grasping of 2- and 3D objects…”
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A lateralized model of the pain-depression dyad by Maallo, Anne Margarette S., Moulton, Eric A., Sieberg, Christine B., Giddon, Donald B., Borsook, David, Holmes, Scott A.

“…•Lateralized non-organic pain is equally probable on either side of the body.•Left hemibody pain is accompanied by greater psychological…”
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Alterations in the structure and function of the brain in adolescents with new daily persistent headache: A pilot MRI study by Szabo, Edina, Chang, Yu‐Hsing Cindy, Shulman, Julie, Sieberg, Christine B., Sethna, Navil F., Borsook, David, Holmes, Scott A., Lebel, Alyssa A.

“…Objective The purpose of this study was to explore brain morphological and functional connectivity alterations in adolescents with new daily persistent…”
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Abnormal functional connectivity and cortical integrity influence dominant hand motor disability in multiple sclerosis: a multimodal analysis by Zhong, Jidan, Nantes, Julia C., Holmes, Scott A., Gallant, Serge, Narayanan, Sridar, Koski, Lisa

“…Functional reorganization and structural damage occur in the brains of people with multiple sclerosis (MS) throughout the disease course. However, the…”
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Biological laterality and peripheral nerve DTI metrics by Holmes, Scott A, Staffa, Steven J, Karapanagou, Anastasia, Lopez, Natalia, Karian, Victoria, Borra, Ronald, Zurakowski, David, Lebel, Alyssa, Borsook, David

“…Clinical comparisons do not usually take laterality into account and thus may report erroneous or misleading data. The concept of laterality, well evaluated in…”
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Evaluating task-based brain network activity in pediatric subjects with an mTBI: mechanisms of functional compensation are symptom-level dependent by Holmes, Scott A., Singh-Saluja, Rajeet, Chen, Jen-kai, Gagnon, Isabelle, Ptito, Alain

“…The diagnosis of a mild traumatic brain injury (mTBI) places large emphasis on patient-reported symptoms which has restricted our ability to evaluate patients…”
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Cortical Damage and Disability in Multiple Sclerosis: Relation to Intracortical Inhibition and Facilitation by Nantes, Julia C, Zhong, Jidan, Holmes, Scott A, Narayanan, Sridar, Lapierre, Yves, Koski, Lisa

“…Highlights • Among people with progressive forms of multiple sclerosis, magnetization transfer ratio (MTR) within the cerebral cortex is related to variability…”
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The visual coding of grip aperture shows an early but not late adherence to Weber's law by Heath, Matthew, Mulla, Ali, Holmes, Scott A., Smuskowitz, Lisa R.

“…▶ The principle of Weber's law was used to examine grip aperture shaping. ▶ We computed just noticeable differences for grasping differently sized objects. ▶…”
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Visually and memory-guided grasping: Aperture shaping exhibits a time-dependent scaling to Weber’s law by Holmes, Scott A., Mulla, Ali, Binsted, Gordon, Heath, Matthew

“…► The principle of Weber’s law was used to examine grip aperture shaping during visually derived and memory-guided actions. ► Just noticeable difference (JNDs)…”
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Distinct Visual Cues Mediate Aperture Shaping for Grasping and Pantomime-Grasping Tasks by Holmes, Scott A., Lohmus, Jennifer, McKinnon, Shelby, Mulla, Ali, Heath, Matthew

“…The authors examined whether the top-down requirements of dissociating the spatial relations between stimulus and response in a goal-directed grasping task…”
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