Search Results - "Holmes, D. T."
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Phosphorylation of intracellular signalling molecules in peripheral blood cells from patients with psoriasis on originator or biosimilar infliximab
Published in British journal of dermatology (1951) (01-08-2018)“…Summary Background Psoriasis vulgaris is a chronic, inflammatory skin disease characterized by a dysregulated immune response and it is associated with…”
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Quetiapine-associated cholestasis causing lipoprotein-X and pseudohyponatraemia
Published in Journal of clinical pathology (01-08-2010)“…A case of intrahepatic cholestasis secondary to treatment with quetiapine in combination with lamotrigine and zopiclone, resulting in severe…”
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Lung Deposition of Droplet Aerosols in Monkeys
Published in Inhalation toxicology (01-01-2008)“…Nonhuman primates are often the animal models of choice to study the infectivity and therapy of inhaled infectious agents. Most animal models for inhaled…”
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Rivaroxaban and apixaban induce clotting factor Xa fibrinolytic activity
Published in Journal of thrombosis and haemostasis (01-11-2018)“…Essentials Activated clotting factor X (FXa) acquires fibrinolytic cofactor function after cleavage by plasmin. FXa‐mediated plasma fibrinolysis is enabled by…”
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Factitious ACTH‐dependent, apparent hypercortisolism: The problem with late‐night salivary cortisol measurements collected at home
Published in Clinical endocrinology (Oxford) (01-12-2017)Get full text
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Controlled infection with a therapeutic virus defines the activation kinetics of human natural killer cells in vivo
Published in Clinical and experimental immunology (01-04-2015)“…Summary Human natural killer (NK) cells play an important role in anti‐viral immunity. However, studying their activation kinetics during infection is highly…”
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Laboratory confirmation of Amanita smithiana mushroom poisoning
Published in Clinical toxicology (Philadelphia, Pa.) (01-05-2013)“…Context. Here we present a case of Amanita smithiana poisoning resulting in acute kidney injury requiring dialysis, and highlight laboratory methods used to…”
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Nephrogenic systemic fibrosis: the story unfolds
Published in Kidney international (01-06-2008)“…The purpose of this Commentary is to briefly summarize the current knowledge of nephrogenic systemic fibrosis in order to promote better understanding of the…”
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Characterization of nasal spray pumps and deposition pattern in a replica of the human nasal airway
Published in Journal of aerosol medicine (01-06-2001)“…Deposition patterns are described of a nasal spray formulation for a novel rhinovirus protease inhibitor. These patterns, which were generated from different…”
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Preliminary Evidence of Psychological Distress among Reservists in the Persian Gulf War
Published in The journal of nervous and mental disease (01-03-1998)“…This study was conducted as a preliminary investigation into the presence and nature of psychological distress among military reserve personnel as a result of…”
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Evaluation of Respirator Filters for Asbestos Fibers
Published in Journal of occupational and environmental hygiene (01-01-2006)“…Fiber aerosols are known to have different aerodynamic behaviors than spherical particles and usually carry higher electrostatic charges. We investigated the…”
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Phospho flow cytometry of PBMCs in psoriasis
Published in British journal of dermatology (1951) (01-08-2018)“…Summary Psoriasis is a chronic inflammatory skin disease, which affects approximately 2% of the population. Severe psoriasis is often treated by inhibition of…”
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Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function
Published in Immunity (Cambridge, Mass.) (17-03-2015)“…The mechanisms underlying human natural killer (NK) cell phenotypic and functional heterogeneity are unknown. Here, we describe the emergence of diverse…”
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NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development
Published in Nature immunology (01-10-2018)“…The activation of natural killer (NK) cells depends on a change in the balance of signals from inhibitory and activating receptors. The activation threshold…”
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Natural killer cell memory in context
Published in Seminars in immunology (01-08-2016)“…Graphical abstract…”
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Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells
Published in Blood (06-04-2017)“…Heterozygous GATA2 mutation is associated with immunodeficiency, lymphedema, and myelodysplastic syndrome. Disease presentation is variable, often coinciding…”
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COPEPTIN IN CKD
Published in Nephrology, dialysis, transplantation (01-05-2014)Get full text
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PBMC磷酸流式细胞术治疗银屑病
Published in British journal of dermatology (1951) (01-08-2018)“…Summary…”
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The Incidence of Enterobius vermicularis in Noninstitutionalized Children in Dayton, Ohio
Published in The Journal of parasitology (01-10-1962)Get full text
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