Search Results - "Holmes, Brittany J"
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Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids
Published in Genome medicine (01-06-2021)“…Metagenomic next-generation sequencing (mNGS) of body fluids is an emerging approach to identify occult pathogens in undiagnosed patients. We hypothesized that…”
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Measurement of fine‐needle aspiration thyroglobulin levels increases the detection of metastatic papillary thyroid carcinoma in cystic neck lesions
Published in Cancer cytopathology (01-07-2014)“…BACKGROUND Patients with previously resected papillary thyroid carcinoma (PTC) are monitored for disease recurrence/metastasis by ultrasound surveillance and…”
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Fine Needle Aspirate of Autoimmune Pancreatitis (Lymphoplasmacytic Sclerosing Pancreatitis): Cytomorphologic Characteristics and Clinical Correlates
Published in Acta cytologica (01-01-2012)“…Objective: Autoimmune pancreatitis (AIP) is an inflammatory, IgG4-associated condition that often overlaps clinically and radiographically with pancreatic…”
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Targeted multiprobe fluorescence in situ hybridization analysis for elucidation of inconclusive pancreatobiliary cytology
Published in Cancer cytopathology (01-08-2014)“…BACKGROUND Endoscopic fine‐needle aspiration (FNA) and brush cytology are standard methods for the diagnosis of pancreatobiliary malignancies. Although the…”
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Performance of the Afirma Gene Expression Classifier in Hürthle Cell Thyroid Nodules Differs from Other Indeterminate Thyroid Nodules
Published in Thyroid (New York, N.Y.) (01-07-2015)“…The recently introduced Afirma gene expression classifier (AGEC) provides binary results (benign or suspicious) to guide management of cytologically…”
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NFE2L2 Mutations Enhance Radioresistance in Head and Neck Cancer by Modulating Intratumoral Myeloid Cells
Published in Cancer research (Chicago, Ill.) (15-03-2023)“…Radiotherapy (RT) is one of the primary treatments of head and neck squamous cell carcinoma (HNSCC), which has a high-risk of locoregional failure (LRF)…”
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Mycotic aortic aneurysm due to intravesical BCG immunotherapy: Clinical manifestations and diagnostic challenges
Published in International journal of mycobacteriology (2014)“…Abstract A live, attenuated form of Mycobacterium bovis , bacillus Calmette–Guérin (BCG), is commonly used as intravesical immunotherapy for non-invasive…”
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The Fidelity of p16 Staining as a Surrogate Marker of Human Papillomavirus Status in Fine-Needle Aspirates and Core Biopsies of Neck Node Metastases: Implications for HPV Testing Protocols
Published in Acta cytologica (01-01-2015)“…Objectives: The importance of detecting human papillomavirus (HPV) in head and neck squamous cell carcinoma (HNSCC) has resulted in a growing expectation for…”
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Macrocystic (Mammary Analogue) Secretory Carcinoma: An Unusual Variant and a Pitfall in the Differential Diagnosis of Cystic Lesions in the Head and Neck
Published in The American journal of surgical pathology (01-11-2019)“…Mammary analogue secretory carcinoma (MASC) is a relatively recently described salivary gland adenocarcinoma characterized by ETV6-NTRK3 gene fusion and in…”
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The expanding role of cytopathology in the diagnosis of HPV-related squamous cell carcinoma of the head and neck
Published in Diagnostic cytopathology (01-01-2014)“…Confirmation of human papillomavirus (HPV) as a causative agent for a subset of biologically and clinically distinct squamous cell carcinomas of the head and…”
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Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC
Published in Molecular & cellular proteomics (01-11-2023)“…The NFE2L2 (NRF2) oncogene and transcription factor drives a gene expression program that promotes cancer progression, metabolic reprogramming, immune evasion,…”
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Virus-associated carcinomas of the head & neck: Update from the 2017 WHO classification
Published in Annals of diagnostic pathology (01-02-2019)“…Virus-associated carcinomas of the head and neck represent an unusual confluence of infections spread by viral transmission and cellular dysregulation…”
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Pilot study of loss of the p53/p63 target gene PERP at the surgical margin as a potential predictor of local relapse in head and neck squamous cell carcinoma
Published in Head & neck (01-11-2020)“…Background PERP (p53 apoptosis effector related to PMP22) localizes to desmosomes and suppresses squamous cell carcinoma development. Loss of PERP leads to…”
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Developing and maintaining protective CD8+ memory T cells
Published in Immunological reviews (01-06-2006)“…A critical aim of vaccine‐related research is to identify the mechanisms by which memory T cells are formed and maintained over long periods of time. In recent…”
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Fine needle aspiration of salivary gland carcinomas with high‐grade transformation: A multi‐institutional study of 22 cases and review of the literature
Published in Cancer cytopathology (01-04-2021)“…Background High‐grade transformation (HGT) is a rare process whereby conventional low‐ to intermediate‐grade salivary gland carcinomas (SGC) transform into…”
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PAX8 Expression in Uterine Adenocarcinomas and Mesonephric Proliferations
Published in International journal of gynecological pathology (01-09-2014)“…PAX8 is a useful immunohistochemical marker for the diagnosis of gynecologic tract malignancies. Several studies have described PAX8 expression in a wide…”
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Novel Cause of Sudden Cardiac Death IgG4-Related Disease
Published in Circulation (New York, N.Y.) (12-06-2012)Get full text
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Mycobacterial spindle cell pseudotumor: Atypical mycobacterial infection mimicking malignancy on fine needle aspiration
Published in Diagnostic cytopathology (01-09-2014)Get full text
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PAX8 Expression in Uterine Malignant Mesodermal Mixed Tumor (Carcinosarcoma)
Published in International journal of gynecological pathology (01-07-2014)“…PAX8 has emerged as a useful immunohistochemical marker for epithelial neoplasms of gynecologic origin. Expression of PAX8 in uterine malignant mesodermal…”
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Xanthogranuloma of Bone: A Challenging Imitator of Malignancy
Published in Acta cytologica (01-01-2013)“…Xanthogranulomatous disease of bone is exceptionally uncommon. Clinically, radiologically and pathologically, it is a great imitator of malignancy. While there…”
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