Search Results - "Holmes, A H"

Antibiotic prescribing in general medical and surgical specialties: a prospective cohort study by Charani, E, de Barra, E, Rawson, T M, Gill, D, Gilchrist, M, Naylor, N R, Holmes, A H

“…Qualitative work has described the differences in prescribing practice across medical and surgical specialties. This study aimed to understand if specialty…”
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Behaviour change interventions to influence antimicrobial prescribing: a cross-sectional analysis of reports from UK state-of-the-art scientific conferences by Rawson, T M, Moore, L S P, Tivey, A M, Tsao, A, Gilchrist, M, Charani, E, Holmes, A H

“…To improve the quality of antimicrobial stewardship (AMS) interventions the application of behavioural sciences supported by multidisciplinary collaboration…”
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Development of PM2.5 source impact spatial fields using a hybrid source apportionment air quality model by Ivey, C E, Holmes, H A, Hu, Y T, Mulholland, J A, Russell, A G

“…An integral part of air quality management is knowledge of the impact of pollutant sources on ambient concentrations of particulate matter (PM). There is also…”
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Forecasting carbapenem resistance from antimicrobial consumption surveillance: Lessons learnt from an OXA-48-producing Klebsiella pneumoniae outbreak in a West London renal unit by Gharbi, M, Moore, L.S.P, Gilchrist, M, Thomas, C.P, Bamford, K, Brannigan, E.T, Holmes, A.H

“…Highlights • We forecast the incidence rate of carbapenem resistance using antimicrobial usage data. • We assess the impact of an antimicrobial stewardship…”
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Funding healthcare-associated infection research: a systematic analysis of UK research investments, 1997–2010 by Head, M.G, Fitchett, J.R, Holmes, A.H, Atun, R

“…Summary Background Healthcare-associated infections (HCAIs) are a cause of high health and economic burden in the UK. The number of HCAI research studies…”
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Machine learning for clinical decision support in infectious diseases: a narrative review of current applications by Peiffer-Smadja, N., Rawson, T.M., Ahmad, R., Buchard, A., Georgiou, P., Lescure, F.-X., Birgand, G., Holmes, A.H.

“…Machine learning (ML) is a growing field in medicine. This narrative review describes the current body of literature on ML for clinical decision support in…”
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The Differences in Antibiotic Decision-making Between Acute Surgical and Acute Medical Teams: An Ethnographic Study of Culture and Team Dynamics by Charani, E, Ahmad, R, Rawson, T M, Castro-Sanchèz, E, Tarrant, C, Holmes, A H

“…Abstract Background Cultural and social determinants influence antibiotic decision-making in hospitals. We investigated and compared cultural determinants of…”
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Understanding antibiotic decision making in surgery—a qualitative analysis by Charani, E., Tarrant, C., Moorthy, K., Sevdalis, N., Brennan, L., Holmes, A.H.

“…To investigate the characteristics and culture of antibiotic decision making in the surgical specialty. A qualitative study including ethnographic observation…”
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A systematic review of clinical decision support systems for antimicrobial management: are we failing to investigate these interventions appropriately? by Rawson, T.M., Moore, L.S.P., Hernandez, B., Charani, E., Castro-Sanchez, E., Herrero, P., Hayhoe, B., Hope, W., Georgiou, P., Holmes, A.H.

“…Clinical decision support systems (CDSS) for antimicrobial management can support clinicians to optimize antimicrobial therapy. We reviewed all original…”
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Descriptive study of selected healthcare-associated infections using national Hospital Episode Statistics data 1996–2006 and comparison with mandatory reporting systems by Jen, M.H, Holmes, A.H, Bottle, A, Aylin, P

“…Summary Using Hospital Episode Statistics (HES) data from England for the period 1996–2006, we performed a descriptive study to compare records of Clostridium…”
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Counting the cost of an outbreak of carbapenemase-producing Enterobacteriaceae: an economic evaluation from a hospital perspective by Otter, J.A., Burgess, P., Davies, F., Mookerjee, S., Singleton, J., Gilchrist, M., Parsons, D., Brannigan, E.T., Robotham, J., Holmes, A.H.

“…To perform an economic evaluation on the cost associated with an outbreak of carbapenemase-producing Enterobacteriaceae (CPE). We performed an observational…”
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Controversies in guidelines for the control of multidrug-resistant Gram-negative bacteria in EU countries by Otter, J.A., Mutters, N.T., Tacconelli, E., Gikas, A., Holmes, A.H.

“…The various guidelines that are available for multidrug-resistant Gram-negative bacteria are useful, and contain broad areas of agreement. However, there are…”
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Hospital-onset COVID-19 infection surveillance systems: a systematic review by Abbas, M., Zhu, N.J., Mookerjee, S., Bolt, F., Otter, J.A., Holmes, A.H., Price, J.R.

“…Hospital-onset COVID-19 infections (HOCIs) are associated with excess morbidity and mortality in patients and healthcare workers. The aim of this review was to…”
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SARS-CoV-2 surface and air contamination in an acute healthcare setting during the first and second pandemic waves by Otter, J.A., Zhou, J., Price, J.R., Reeves, L., Zhu, N., Randell, P., Sriskandan, S., Barclay, W.S., Holmes, A.H.

“…Surfaces and air in healthcare facilities can be contaminated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Previously, the authors…”
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Supervised machine learning for the prediction of infection on admission to hospital: a prospective observational cohort study by Rawson, T M, Hernandez, B, Moore, L S P, Blandy, O, Herrero, P, Gilchrist, M, Gordon, A, Toumazou, C, Sriskandan, S, Georgiou, P, Holmes, A H

“…Abstract Background Infection diagnosis can be challenging, relying on clinical judgement and non-specific markers of infection. We evaluated a supervised…”
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The Chennai Declaration: India's landmark national commitment to antibiotic stewardship demonstrates that 'truth alone triumphs' by Holmes, A H, Sharland, M

“…A joint meeting of the medical societies in India took place in Chennai in August 2012, giving rise to national recommendations and an action plan to address…”
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Innovative tools for quality assessment: integrated quality criteria for review of multiple study designs (ICROMS) by Zingg, W, Castro-Sanchez, E, Secci, F.V, Edwards, R, Drumright, L.N, Sevdalis, N, Holmes, A.H

“…Abstract Objectives With the aim to facilitate a more comprehensive review process in public health including patient safety, we established a tool that we…”
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Towards changing healthcare workers' behaviour: a qualitative study exploring non-compliance through appraisals of infection prevention and control practices by Shah, N, Castro-Sánchez, E, Charani, E, Drumright, L.N, Holmes, A.H

“…Summary Background Improving behaviour in infection prevention and control (IPC) practice remains a challenge, and understanding the determinants of healthcare…”
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Effect of adding a mobile health intervention to a multimodal antimicrobial stewardship programme across three teaching hospitals: an interrupted time series study by Charani, E, Gharbi, M, Moore, L S P, Castro-Sanchéz, E, Lawson, W, Gilchrist, M, Holmes, A H

“…To evaluate the impact of adding a mobile health (mHealth) decision support system for antibiotic prescribing to an established antimicrobial stewardship…”
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Factors that impact on the burden of Escherichia coli bacteraemia: multivariable regression analysis of 2011–2015 data from West London by Blandy, O., Honeyford, K., Gharbi, M., Thomas, A., Ramzan, F., Ellington, M.J., Hope, R., Holmes, A.H., Johnson, A.P., Aylin, P., Woodford, N., Sriskandan, S.

“…The incidence of Escherichia coli bacteraemia in England is increasing amid concern regarding the roles of antimicrobial resistance and nosocomial acquisition…”
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