Search Results - "Holme, A"
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Potential role of polycyclic aromatic hydrocarbons in air pollution-induced non-malignant respiratory diseases
Published in Respiratory research (13-11-2020)“…Epidemiological studies have found strong associations between air pollution and respiratory effects including development and/or exacerbation of asthma and…”
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Potential role of polycyclic aromatic hydrocarbons as mediators of cardiovascular effects from combustion particles
Published in Environmental health (22-08-2019)“…Air pollution is the most important environmental risk factor for disease and premature death, and exposure to combustion particles from vehicles is a major…”
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3
Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
Published in The New England journal of medicine (03-06-2021)“…This report describes a very rare but life-threatening sequela of vaccination with ChAdOx1 nCoV-19. Within 10 days after a first injection, five health care…”
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4
Effects of particulate matter on atherosclerosis: a link via high-density lipoprotein (HDL) functionality?
Published in Particle and fibre toxicology (04-08-2020)“…Exposure to air pollution has been associated with adverse effects on human health, and ultimately increased morbidity and mortality. This is predominantly due…”
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5
Mechanisms of Action and Toxicity of the Mycotoxin Alternariol: A Review
Published in Basic & clinical pharmacology & toxicology (01-12-2016)“…The mycotoxin alternariol (AOH) is produced by Alternaria fungi. It occurs naturally in foodstuffs and is frequently found as contaminant in fruit and grain…”
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6
Pro-inflammatory effects of crystalline- and nano-sized non-crystalline silica particles in a 3D alveolar model
Published in Particle and fibre toxicology (21-04-2020)“…Silica nanoparticles (SiNPs) are among the most widely manufactured and used nanoparticles. Concerns about potential health effects of SiNPs have therefore…”
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Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved
Published in Particle and fibre toxicology (19-12-2013)“…This study explores and characterizes cell cycle alterations induced by urban PM2.5 in the human epithelial cell line BEAS-2B, and elucidates possible…”
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Physico-chemical properties and biological effects of diesel and biomass particles
Published in Environmental pollution (1987) (01-08-2016)“…Diesel combustion and solid biomass burning are the major sources of ultrafine particles (UFP) in urbanized areas. Cardiovascular and pulmonary diseases,…”
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Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of the In Vivo and In Vitro Studies
Published in BioMed research international (01-01-2013)“…Epidemiological and clinical studies have linked exposure to particulate matter (PM) to adverse health effects, which may be registered as increased mortality…”
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Adverse neurodevelopment in children associated with prenatal exposure to fine particulate matter (PM2.5) – Possible roles of polycyclic aromatic hydrocarbons (PAHs) and mechanisms involved
Published in Reproductive toxicology (Elmsford, N.Y.) (01-12-2024)“…Prenatal exposure to ambient fine particles (PM2.5) and polycyclic aromatic hydrocarbons (PAHs) has been associated with adverse birth outcomes including…”
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Milan winter fine particulate matter (wPM2.5) induces IL-6 and IL-8 synthesis in human bronchial BEAS-2B cells, but specifically impairs IL-8 release
Published in Toxicology in vitro (01-10-2018)“…Inflammatory responses have an important role in the onset of many lung diseases associated with urban airborne particulate matter (PM). Here we investigate…”
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Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)
Published in Particle and fibre toxicology (11-05-2018)“…Exposure to traffic-derived particulate matter (PM), such as diesel exhaust particles (DEP), is a leading environmental cause of cardiovascular disease (CVD),…”
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13
Role for membrane remodeling in cell death: Implication for health and disease
Published in Toxicology (Amsterdam) (08-02-2013)“…Abstract Recently it has become clear that exposure to xenobiotics may result in various forms of cell death; not only passive cell deaths like necrosis, or…”
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Role of different mechanisms in pro-inflammatory responses triggered by traffic-derived particulate matter in human bronchiolar epithelial cells
Published in Particle and fibre toxicology (03-08-2023)“…Traffic-derived particles are important contributors to the adverse health effects of ambient particulate matter (PM). In Nordic countries, mineral particles…”
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15
A Dominant STIM1 Mutation Causes Stormorken Syndrome
Published in Human mutation (01-05-2014)“…ABSTRACT Stormorken syndrome is a rare autosomal‐dominant disease with mild bleeding tendency, thrombocytopathy, thrombocytopenia, mild anemia, asplenia,…”
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Activation of Proinflammatory Responses in Cells of the Airway Mucosa by Particulate Matter: Oxidant- and Non-Oxidant-Mediated Triggering Mechanisms
Published in Biomolecules (Basel, Switzerland) (02-07-2015)“…Inflammation is considered to play a central role in a diverse range of disease outcomes associated with exposure to various types of inhalable particulates…”
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Lung cancer associated with combustion particles and fine particulate matter (PM2.5) - The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl hydrocarbon receptor (AhR)
Published in Biochemical pharmacology (01-10-2023)“…[Display omitted] Air pollution is the leading cause of lung cancer after tobacco smoking, contributing to 20% of all lung cancer deaths. Increased risk…”
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Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia
Published in European heart journal (14-10-2021)“…Abstract Aims We recently reported five cases of vaccine-induced immune thrombotic thrombocytopenia (VITT) 7–10 days after receiving the first dose of the…”
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Use of Swedish smokeless tobacco during pregnancy: A systematic review of pregnancy and early life health risk
Published in Addiction (Abingdon, England) (01-05-2023)“…Background and Aims Smokeless tobacco is a heterogeneous product group with diverse composition and prevalence globally. Tobacco use during pregnancy is…”
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Road tunnel-derived coarse, fine and ultrafine particulate matter: physical and chemical characterization and pro-inflammatory responses in human bronchial epithelial cells
Published in Particle and fibre toxicology (04-07-2022)“…Traffic particulate matter (PM) comprises a mixture of particles from fuel combustion and wear of road pavement, tires and brakes. In countries with low winter…”
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