Search Results - "Holmberg, Steen"

The Cyclin-Dependent Kinase 8 Module Sterically Blocks Mediator Interactions with RNA Polymerase II by Elmlund, Hans, Baraznenok, Vera, Lindahl, Martin, Samuelsen, Camilla O., Koeck, Philip J. B., Holmberg, Steen, Hebert, Hans, Gustafsson, Claes M.

“…CDK8 (cyclin-dependent kinase 8), along with CycC, Med12, and Med13, form a repressive module (the Cdk8 module) that prevents RNA polymerase II (pol II)…”
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Mediator regulates non-coding RNA transcription at fission yeast centromeres by Thorsen, Michael, Hansen, Heidi, Venturi, Michela, Holmberg, Steen, Thon, Genevieve

“…In fission yeast, centromeric heterochromatin is necessary for the fidelity of chromosome segregation. Propagation of heterochromatin in dividing cells…”
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MRN1 implicates chromatin remodeling complexes and architectural factors in mRNA maturation by Düring, Louis, Thorsen, Michael, Petersen, Darima Sophia Njama, Køster, Brian, Jensen, Torben Heick, Holmberg, Steen

“…A functional relationship between chromatin structure and mRNA processing events has been suggested, however, so far only a few involved factors have been…”
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TRAP230/ARC240 and TRAP240/ARC250 Mediator Subunits Are Functionally Conserved through Evolution by Samuelsen, Camilla O., Baraznenok, Vera, Khorosjutina, Olga, Spåhr, Henrik, Kieselbach, Thomas, Holmberg, Steen, Gustafsson, Claes M.

“…In Saccharomyces cerevisiae Mediator, a subgroup of proteins (Srb8, Srb9, Srb10, and Srb11) form a module, which is involved in negative regulation of…”
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Two conserved modules of Schizosaccharomyces pombe Mediator regulate distinct cellular pathways by Linder, Tomas, Rasmussen, Nina N, Samuelsen, Camilla O, Chatzidaki, Emmanouella, Baraznenok, Vera, Beve, Jenny, Henriksen, Peter, Gustafsson, Claes M, Holmberg, Steen

“…Mediator is an evolutionary conserved coregulator complex required for transcription of almost all RNA polymerase II-dependent genes. The Schizosaccharomyces…”
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Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae by Regenberg, B, During-Olsen, L, Kielland-Brandt, M.C, Holmberg, S

“…All known amino-acid permeases (AAPs) in Saccharomyces cerevisiae belong to a single family of homologous proteins. Genes of 15 AAPs were overexpressed in…”
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Mediator Influences Schizosaccharomyces pombe RNA Polymerase II-dependent Transcription in Vitro by Spåhr, Henrik, Khorosjutina, Olga, Baraznenok, Vera, Linder, Tomas, Samuelsen, Camilla O., Hermand, Damien, Mäkelä, Tomi P., Holmberg, Steen, Gustafsson, Claes M.

“…The fission yeast Schizosaccharomyces pombe has proved an important model system for cross-species comparative studies of many fundamental processes in the…”
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Analysis of Schizosaccharomyces pombe Mediator Reveals a Set of Essential Subunits Conserved between Yeast and Metazoan Cells by Spåhr, Henrik, Samuelsen, Camilla O., Baraznenok, Vera, Ernest, Isabelle, Huylebroeck, Danny, Remacle, Jacques E., Samuelsson, Tore, Kieselbach, Thomas, Holmberg, Steen, Gustafsson, Claes M.

“…With the identification of eight new polypeptides, we here complete the subunit characterization of the Schizosaccharomyces pombe RNA polymerase II holoenzyme…”
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Neither Reb1p nor Poly(dA·dT) Elements Are Responsible for the Highly Specific Chromatin Organization at the ILV1Promoter by Moreira, José M.A., Hörz, Wolfram, Holmberg, Steen

“…Analysis of the chromatin structure at the yeastILV1 locus revealed highly positioned nucleosomes covering the entire locus except for a hypersensitive site in…”
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Dip5p mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate in Saccharomyces cerevisiae by Regenberg, B, Holmberg, S, Olsen, L D, Kielland-Brandt, M C

“…Genes encoding homologues of known amino-acid permeases were deleted in a strain also deficient in the general amino-acid permease. The uptake capacity of the…”
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Yeast Transcriptional Regulator Leu3p by Wang, Dake, Zheng, Feng, Holmberg, Steen, Kohlhaw, Gunter B.

“…Recent work suggests that the masking of the activation domain (AD) of yeast transactivator Leu3p, observed in the absence of the metabolic signal…”
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Genome-Wide Occupancy Profile of Mediator and the Srb8-11 Module Reveals Interactions with Coding Regions by Zhu, Xuefeng, Wirén, Marianna, Sinha, Indranil, Rasmussen, Nina N., Linder, Tomas, Holmberg, Steen, Ekwall, Karl, Gustafsson, Claes M.

“…Mediator exists in a free form containing the Med12, Med13, CDK8, and CycC subunits (the Srb8-11 module) and a smaller form, which lacks these four subunits…”
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A Unified Nomenclature for Protein Subunits of Mediator Complexes Linking Transcriptional Regulators to RNA Polymerase II by Bourbon, Henri-Marc, Aguilera, Andres, Ansari, Aseem Z., Asturias, Francisco J., Berk, Arnold J., Bjorklund, Stefan, Blackwell, T.Keith, Borggrefe, Tilman, Carey, Michael, Carlson, Marian, Conaway, Joan W., Conaway, Ronald C., Emmons, Scott W., Fondell, Joseph D., Freedman, Leonard P., Fukasawa, Toshio, Gustafsson, Claes M., Han, Min, He, Xi, Herman, Paul K., Hinnebusch, Alan G., Holmberg, Steen, Holstege, Frank C., Jaehning, Judith A., Kim, Young-Joon, Kuras, Laurent, Leutz, Achim, Lis, John T., Meisterernest, Michael, Naar, Anders M., Nasmyth, Kim, Parvin, Jeffrey D., Ptashne, Mark, Reinberg, Danny, Ronne, Hans, Sadowski, Ivan, Sakurai, Hiroshi, Sipiczki, Matthias, Sternberg, Paul W., Stillman, David J., Strich, Randy, Struhl, Kevin, Svejstrup, Jasper Q., Tuck, Simon, Winston, Fred, Roeder, Robert G., Kornberg, Roger D.

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Regulated overproduction and secretion of yeast carboxypeptidase Y by NIELSEN, T. L, HOLMBERG, S, PETERSEN, J. G. L

“…Carboxypeptidase Y (CPY) is a glycosylated yeast vacuolar protease used commercially for synthesis of peptides. To increase the production of CPY in…”
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Regulation of isoleucine-valine biosynthesis in Saccharomyces cerevisiae by Holmberg, S, Petersen, J.G.L

“…The threonine deaminase gene (ILV1) of Saccharomyces cerevisiae has been designated "multifunctional" since Bollon (1974) indicated its involvement both in the…”
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Comparative Amino Acid Sequence Analysis of the C6 Zinc Cluster Family of Transcriptional Regulators by Schjerling, Peter, Holmberg, Steen

“…The C6 zinc cluster family of fungal regulatory proteins shares as DNA-binding motif the C6 zinc cluster, also known as the Zn(II)2Cys6 binuclear cluster. This…”
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Towards diacetyl-less brewers' yeast. Influence of ilv2 and ilv5 mutations by Gjermansen, C, Nilsson-Tillgren, T, Petersen, J G, Kielland-Brandt, M C, Sigsgaard, P, Holmberg, S

“…During alcoholic fermentations, the off-flavour compound diacetyl is formed non-enzymatically from acetolactate leaking out from the cells. Acetolactate is an…”
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Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC by Moreira, J.M.A, Holmberg, S

“…In eukaryotes, DNA is packaged into chromatin, a compact structure that must be disrupted when genes are transcribed by RNA polymerase II. For transcription to…”
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Nucleosome structure of the yeast CHA1 promoter: analysis of activation-dependent chromatin remodeling of an RNA-polymerase-II-transcribed gene in TBP and RNA pol II mutants defective in vivo in response to acidic activators by Moreira, J.M.A, Holmberg, S

“…The Saccharomyces cerevisiae CHA1 gene encodes the catabolic L‐serine (L‐threonine) dehydratase. We have previously shown that the transcriptional activator…”
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Chromatin-mediated transcriptional regulation by the yeast architectural factors NHP6A and NHP6B by Moreira, José M. A., Holmberg, Steen

“…The Saccharomyces cerevisiae NHP6A and NHP6B proteins are chromatin architectural factors, functionally and structurally related to the mammalian high mobility…”
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