Search Results - "Holman, Derek R."

Antimicrobial peptides and the gut microbiome in inflammatory bowel disease by Gubatan, John, Holman, Derek R, Puntasecca, Christopher J, Polevoi, Danielle, Rubin, Samuel JS, Rogalla, Stephan

“…Antimicrobial peptides (AMP) are highly diverse and dynamic molecules that are expressed by specific intestinal epithelial cells, Paneth cells, as well as…”
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Automated spatial omics landscape analysis approach reveals novel tissue architectures in ulcerative colitis by Holman, Derek R., Rubin, Samuel J. S., Ferenc, Mariusz, Holman, Elizabeth A., Koron, Alexander N., Daniel, Robel, Boland, Brigid S., Nolan, Garry P., Chang, John T., Rogalla, Stephan

“…The utility of spatial omics in leveraging cellular interactions in normal and diseased states for precision medicine is hampered by a lack of strategies for…”
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Gut Microbiome in Inflammatory Bowel Disease: Role in Pathogenesis, Dietary Modulation, and Colitis-Associated Colon Cancer by Gubatan, John, Boye, Theresa Louise, Temby, Michelle, Sojwal, Raoul S, Holman, Derek R, Sinha, Sidhartha R, Rogalla, Stephan R, Nielsen, Ole Haagen

“…The gut microbiome has increasingly been recognized as a critical and central factor in inflammatory bowel disease (IBD). Here, we review specific…”
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Neuronal and vascular deficits following chronic adaptation to high altitude by Cramer, Nathan P., Korotcov, Alexandru, Bosomtwi, Asamoah, Xu, Xiufen, Holman, Derek R., Whiting, Kathleen, Jones, Scott, Hoy, Andrew, Dardzinski, Bernard J., Galdzicki, Zygmunt

“…We sought to understand the mechanisms underlying cognitive deficits that are reported to affect non-native subjects following their prolonged stay and/or work…”
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Highlighting the Undetectable — Fluorescence Molecular Imaging in Gastrointestinal Endoscopy by Stibbe, Judith A., Hoogland, Petra, Achterberg, Friso B., Holman, Derek R., Sojwal, Raoul S., Burggraaf, Jacobus, Vahrmeijer, Alexander L., Nagengast, Wouter B., Rogalla, Stephan

“…Flexible high-definition white-light endoscopy is the current gold standard in screening for cancer and its precursor lesions in the gastrointestinal tract…”
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A tissue atlas of ulcerative colitis revealing evidence of sex-dependent differences in disease-driving inflammatory cell types and resistance to TNF inhibitor therapy by Mayer, Aaron T, Holman, Derek R, Sood, Anav, Tandon, Utkarsh, Bhate, Salil S, Bodapati, Sunil, Barlow, Graham L, Chang, Jeff, Black, Sarah, Crenshaw, Erica C, Koron, Alexander N, Streett, Sarah E, Gambhir, Sanjiv S, Sandborn, William J, Boland, Brigid S, Hastie, Trevor, Tibshirani, Robert, Chang, John T, Nolan, Garry P, Schürch, Christian M, Rogalla, Stephan

“…Although literature suggests that resistance to TNF inhibitor (TNFi) therapy in patients with ulcerative colitis (UC) is partially linked to immune cell…”
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Rapid assessment of changes in phage bioactivity using dynamic light scattering by Dharmaraj, Tejas, Kratochvil, Michael J, Pourtois, Julie D, Chen, Qingquan, Hajfathalian, Maryam, Hargil, Aviv, Lin, Yung-Hao, Evans, Zoe, Oromí-Bosch, Agnès, Berry, Joel D, McBride, Robert, Haddock, Naomi L, Holman, Derek R, van Belleghem, Jonas D, Chang, Tony H, Barr, Jeremy J, Lavigne, Rob, Heilshorn, Sarah C, Blankenberg, Francis G, Bollyky, Paul L

“…Extensive efforts are underway to develop bacteriophages as therapies against antibiotic-resistant bacteria. However, these efforts are confounded by the…”
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Identification of Recently Handled Materials by Analysis of Latent Human Fingerprints Using Infrared Spectromicroscopy by Grant, Ashleigh, Wilkinson, T. J., Holman, Derek R., Martin, Michael C.

“…Analysis of fingerprints has predominantly focused on matching the pattern of ridges to a specific person as a form of identification. The present work focuses…”
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Expanding hyperspectral imaging applications to the clinical scene: non-invasive, label-free approaches for early diagnostics and precision medicine by Holman, Elizabeth A., Holman, Derek R., Rogalla, Stephan

“…Non-invasive, label-free hyperspectral imaging technologies are powerful tools that can provide critical insights into the spatiotemporal dynamics of evolving…”
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