Search Results - "Holm, Niels V."
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Familial Risk and Heritability of Cancer Among Twins in Nordic Countries
Published in JAMA : the journal of the American Medical Association (05-01-2016)“…IMPORTANCE: Estimates of familial cancer risk from population-based studies are essential components of cancer risk prediction. OBJECTIVE: To estimate familial…”
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The heritability of prostate cancer in the Nordic Twin Study of Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-11-2014)“…Prostate cancer is thought to be the most heritable cancer, although little is known about how this genetic contribution varies across age. To address this…”
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Prognostic Factors and Treatment Results After Bleomycin, Etoposide, and Cisplatin in Germ Cell Cancer: A Population-based Study
Published in European urology (01-02-2017)“…Abstract Background First-line treatment for patients with disseminated germ cell cancer (GCC) is bleomycin, etoposide, and cisplatin (BEP). A prognostic…”
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The Danish Twin Registry: Linking Surveys, National Registers, and Biological Information
Published in Twin research and human genetics (01-02-2013)“…Over the last 60 years, the resources and the research in the Danish Twin Registry (DTR) have periodically been summarized. Here, we give a short overview of…”
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Biodemographic Trajectories of Longevity
Published in Science (American Association for the Advancement of Science) (08-05-1998)“…Old-age survival has increased substantially since 1950. Death rates decelerate with age for insects, worms, and yeast, as well as humans. This evidence of…”
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The Danish Twin Registry: An Updated Overview
Published in Twin research and human genetics (01-12-2019)“…The Danish Twin Registry (DTR) was established in the 1950s, when twins born from 1870 to 1910 were ascertained, and has since been extended to include twins…”
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Sexual Function in a Nationwide Cohort of 2,260 Survivors of Testicular Cancer after 17 Years of Followup
Published in The Journal of urology (01-10-2018)“…Evidence on the long-term impact of testicular cancer treatment on sexual function is not clear. Our aim was to estimate the effect of testicular cancer…”
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The Heritability of Breast Cancer among Women in the Nordic Twin Study of Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-01-2016)“…Family history is an established risk factor for breast cancer. Although some important genetic factors have been identified, the extent to which familial risk…”
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Surveillance versus adjuvant radiotherapy for patients with high‐risk stage I seminoma
Published in Cancer (01-04-2017)“…BACKGROUND The optimal treatment strategy for patients with clinical stage I (CS‐1) seminoma is controversial. The objective of the current study was to…”
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Germ Cell Cancer and Multiple Relapses: Toxicity and Survival
Published in Journal of clinical oncology (01-10-2015)“…A small number of patients with germ cell cancer (GCC) receive more than one line of treatment for disseminated disease. The purpose of this study was to…”
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Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland
Published in The New England journal of medicine (13-07-2000)“…Except for certain types of familial cancer, such as adenomatous polyposis coli, the contribution of hereditary factors to the development of cancer is thought…”
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Psychological stress in long-term testicular cancer survivors: a Danish nationwide cohort study
Published in Journal of cancer survivorship (01-02-2020)“…Purpose Long-term cancer survivors may develop psychological late effects. The aim of the present study was to determine prevalence of high level of stress in…”
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Second Malignant Neoplasms and Cause of Death in Patients With Germ Cell Cancer: A Danish Nationwide Cohort Study
Published in JAMA oncology (01-12-2016)“…Patients given systemic treatment for testicular germ cell cancer (GCC) are at increased risk for a second malignant neoplasm (SMN). Previous studies on SMN…”
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Cancer Incidence and Mortality in 260,000 Nordic Twins With 30,000 Prospective Cancers
Published in Twin research and human genetics (01-04-2019)“…The Nordic countries have comprehensive, population-based health and medical registries linkable on individually unique personal identity codes, enabling…”
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Sexual Function and Quality of Life in a National Cohort of Survivors of Bilateral Testicular Cancer
Published in European urology focus (15-07-2020)“…Sexual function and quality of life remain unexplored among long-term survivors of bilateral testicular cancer (TC). To investigate sexual function, fatigue,…”
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Register-based research on twins
Published in Scandinavian journal of public health (01-07-2011)“…Introduction: The Danish Twin Registry (DTR) has for more than 50 years been based on surveys and clinical investigations and over the two last decades also on…”
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Trends in tumors in the central nervous system in elderly in Denmark, 2008-2012
Published in Acta oncologica (22-01-2016)“…Tumors in the central nervous system (CNS) comprise a heterogeneous group of tumors with different treatment strategies and prognoses. Current treatment…”
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Cancer and longevity--is there a trade-off? A study of cooccurrence in Danish twin pairs born 1900-1918
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-05-2012)“…Animal models and a few human studies have suggested a complex interaction between cancer risk and longevity indicating a trade-off where low cancer risk is…”
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The heritability of human longevity : a population-based study of 2872 Danish twin pairs born 1870-1900
Published in Human genetics (01-03-1996)“…The aim of this study was to explore, in a large and non-censored twin cohort, the nature (i.e., additive versus non-additive) and magnitude (i.e.,…”
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Relative importance of genetic effects in rheumatoid arthritis: historical cohort study of Danish nationwide twin population
Published in BMJ (02-02-2002)“…Abstract Objective: To determine the relative importance of environmental and genetic effects in the development of rheumatoid arthritis. Design: Historical…”
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