Search Results - "Holly K Gildea"

Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2 by Jaworski, Alexander, Tom, Irene, Tong, Raymond K., Gildea, Holly K., Koch, Alexander W., Gonzalez, Lino C., Tessier-Lavigne, Marc

“…Axon pathfinding is orchestrated by numerous guidance cues, including Slits and their Robo receptors, but it remains unclear how information from multiple cues…”
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Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples by Hamilton, Jennifer R, Stahl, Elizabeth C, Tsuchida, Connor A, Lin-Shiao, Enrique, Tsui, C Kimberly, Pestal, Kathleen, Gildea, Holly K, Witkowsky, Lea B, Moehle, Erica A, McDevitt, Shana L, McElroy, Matthew, Keller, Amanda, Sylvain, Iman, Hirsh, Ariana, Ciling, Alison, Ehrenberg, Alexander J, Ringeisen, Bradley R, Huberty, Garth, Urnov, Fyodor D, Giannikopoulos, Petros, Doudna, Jennifer A

“…Saliva is an attractive specimen type for asymptomatic surveillance of COVID-19 in large populations due to its ease of collection and its demonstrated utility…”
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SKN-1 regulates stress resistance downstream of amino catabolism pathways by Frankino, Phillip A., Siddiqi, Talha F., Bolas, Theodore, Bar-Ziv, Raz, Gildea, Holly K., Zhang, Hanlin, Higuchi-Sanabria, Ryo, Dillin, Andrew

“…The deleterious potential to generate oxidative stress is a fundamental challenge to metabolism. The oxidative stress response transcription factor,…”
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Four glial cells regulate ER stress resistance and longevity via neuropeptide signaling in C. elegans by Frakes, Ashley E, Metcalf, Melissa G, Tronnes, Sarah U, Bar-Ziv, Raz, Durieux, Jenni, Gildea, Holly K, Kandahari, Nazineen, Monshietehadi, Samira, Dillin, Andrew

“…The ability of the nervous system to sense cellular stress and coordinate protein homeostasis is essential for organismal health. Unfortunately, stress…”
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Protein homeostasis from the outside in by Webster, Brant M., Gildea, Holly K., Dillin, Andrew

“…Secretory proteins undergo multiple rounds of co- and post-translational quality control checks inside the cell, but how their integrity is maintained outside…”
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Aging alters the metabolic flux signature of the ER‐unfolded protein response in vivo in mice by Ward, Catherine P., Peng, Lucy, Yuen, Samuel, Halstead, John, Palacios, Hector, Nyangau, Edna, Mohammed, Hussein, Ziari, Naveed, Dandan, Mohamad, Frakes, Ashley E., Gildea, Holly K., Dillin, Andrew, Hellerstein, Marc K.

“…Age is a risk factor for numerous diseases, including neurodegenerative diseases, cancers, and diabetes. Loss of protein homeostasis is a central hallmark of…”
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Measurements of Physiological Stress Responses in C. Elegans by Bar-Ziv, Raz, Frakes, Ashley E, Higuchi-Sanabria, Ryo, Bolas, Theodore, Frankino, Phillip A, Gildea, Holly K, Metcalf, Melissa G, Dillin, Andrew

“…Organisms are often exposed to fluctuating environments and changes in intracellular homeostasis, which can have detrimental effects on their proteome and…”
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Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples by Jennifer R Hamilton, Elizabeth C Stahl, Connor A Tsuchida, Enrique Lin-Shiao, C Kimberly Tsui, Kathleen Pestal, Holly K Gildea, Lea B Witkowsky, Erica A Moehle, Shana L McDevitt, Matthew McElroy, Amanda Keller, Iman Sylvain, Ariana Hirsh, Alison Ciling, Alexander J Ehrenberg, Bradley R Ringeisen, Garth Huberty, Fyodor D Urnov, Petros Giannikopoulos, Jennifer A Doudna, IGI SARS-CoV-2 Consortium

“…Saliva is an attractive specimen type for asymptomatic surveillance of COVID-19 in large populations due to its ease of collection and its demonstrated utility…”
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Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus by Ehrenberg, Alexander J, Moehle, Erica A, Brook, Cara E, Doudna Cate, Andrew H, Witkowsky, Lea B, Sachdeva, Rohan, Hirsh, Ariana, Barry, Kerrie, Hamilton, Jennifer R, Lin-Shiao, Enrique, McDevitt, Shana, Valentin-Alvarado, Luis, Letourneau, Kaitlyn N, Hunter, Lauren, Keller, Amanda, Pestal, Kathleen, Frankino, Phillip A, Murley, Andrew, Nandakumar, Divya, Stahl, Elizabeth C, Tsuchida, Connor A, Gildea, Holly K, Murdock, Andrew G, Hochstrasser, Megan L, O'Brien, Elizabeth, Ciling, Alison, Tsitsiklis, Alexandra, Worden, Kurtresha, Dugast-Darzacq, Claire, Hays, Stephanie G, Barber, Colin C, McGarrigle, Riley, Lam, Emily K, Ensminger, David C, Bardet, Lucie, Sherry, Carolyn, Harte, Anna, Nicolette, Guy, Giannikopoulos, Petros, Hockemeyer, Dirk, Petersen, Maya, Urnov, Fyodor D, Ringeisen, Bradley R, Boots, Mike, Doudna, Jennifer A

“…Regular surveillance testing of asymptomatic individuals for SARS-CoV-2 has been center to SARS-CoV-2 outbreak prevention on college and university campuses…”
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LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples by Stahl, Elizabeth C, Gopez, Allan R, Tsuchida, Connor A, Fan, Vinson B, Moehle, Erica A, Witkowsky, Lea B, Hamilton, Jennifer R, Lin-Shiao, Enrique, McElroy, Matthew, McDevitt, Shana L, Ciling, Alison, Tsui, C Kimberly, Pestal, Kathleen, Gildea, Holly K, Keller, Amanda, Sylvain, Iman A, Williams, Clara, Hirsh, Ariana, Ehrenberg, Alexander J, Kantor, Rose, Metzger, Matthew, Nelson, Kara L, Urnov, Fyodor D, Ringeisen, Bradley R, Giannikopoulos, Petros, Doudna, Jennifer A

“…Clinical and surveillance testing for the SARS-CoV-2 virus relies overwhelmingly on RT-qPCR-based diagnostics, yet several popular assays require 2-3 separate…”
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Glia of C. elegans coordinate a protective organismal heat shock response independent of the neuronal thermosensory circuit by Gildea, Holly K, Frankino, Phillip A, Tronnes, Sarah U, Pender, Corinne L, Durieux, Jenni, Dishart, Julian G, Choi, Hyun Ok, Hunter, Tayla D, Cheung, Shannon S, Frakes, Ashley E, Sukarto, Edward, Wickham, Kevin, Dillin, Andrew

“…Aging organisms lose the ability to induce stress responses, becoming vulnerable to protein toxicity and tissue damage. Neurons can signal to peripheral…”
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LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples by Elizabeth C. Stahl, Allan R. Gopez, Connor A. Tsuchida, Vinson B. Fan, Erica A. Moehle, Lea B. Witkowsky, Jennifer R. Hamilton, Enrique Lin-Shiao, Matthew McElroy, Shana L. McDevitt, Alison Ciling, C. Kimberly Tsui, Kathleen Pestal, Holly K. Gildea, Amanda Keller, Iman A. Sylvain, Clara Williams, Ariana Hirsh, Alexander J. Ehrenberg, Rose Kantor, Matthew Metzger, Kara L. Nelson, Fyodor D. Urnov, Bradley R. Ringeisen, Petros Giannikopoulos, Jennifer A. Doudna, IGI Testing Consortium

“…Clinical and surveillance testing for the SARS-CoV-2 virus relies overwhelmingly on RT-qPCR-based diagnostics, yet several popular assays require 2–3 separate…”
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