Search Results - "Holloway, Alison"

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    Fluoxetine-induced hepatic lipid accumulation is linked to elevated serotonin production by Ayyash, Ahmed, Holloway, Alison C

    “…Fluoxetine, a commonly prescribed selective serotonin reuptake inhibitor antidepressant, has been shown to increase hepatic lipid accumulation, a key factor in…”
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    Fluoxetine‐induced hepatic lipid accumulation is mediated by prostaglandin endoperoxide synthase 1 and is linked to elevated 15‐deoxy‐Δ12,14PGJ2 by Ayyash, Ahmed, Holloway, Alison C.

    Published in Journal of applied toxicology (01-06-2022)
    “…Major depressive disorder and other neuropsychiatric disorders are often managed with long‐term use of antidepressant medication. Fluoxetine, an SSRI…”
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    Δ9-tetrahydrocannabinol exposure during rat pregnancy leads to symmetrical fetal growth restriction and labyrinth-specific vascular defects in the placenta by Natale, Bryony V., Gustin, Katarina N., Lee, Kendrick, Holloway, Alison C., Laviolette, Steven R., Natale, David R. C., Hardy, Daniel B.

    Published in Scientific reports (17-01-2020)
    “…1 in 5 women report cannabis use during pregnancy, with nausea cited as their primary motivation. Studies show that (-)-△9–tetrahydrocannabinol (Δ9-THC ), the…”
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    Early Life Exposure to Nicotine: Postnatal Metabolic, Neurobehavioral and Respiratory Outcomes and the Development of Childhood Cancers by Jamshed, Laiba, Perono, Genevieve A, Jamshed, Shanza, Holloway, Alison C

    Published in Toxicological sciences (01-11-2020)
    “…Abstract Cigarette smoking during pregnancy is associated with numerous obstetrical, fetal, and developmental complications, as well as an increased risk of…”
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    Long-Term Consequences of Fetal and Neonatal Nicotine Exposure: A Critical Review by Bruin, Jennifer E., Gerstein, Hertzel C., Holloway, Alison C.

    Published in Toxicological sciences (01-08-2010)
    “…Cigarette smoking during pregnancy is associated with numerous obstetrical, fetal, and developmental complications, as well as an increased risk of adverse…”
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    Fluoxetine-induced hepatic lipid accumulation is mediated by prostaglandin endoperoxide synthase 1 and is linked to elevated 15-deoxy-Δ 12,14 PGJ 2 by Ayyash, Ahmed, Holloway, Alison C

    Published in Journal of applied toxicology (01-06-2022)
    “…Major depressive disorder and other neuropsychiatric disorders are often managed with long-term use of antidepressant medication. Fluoxetine, an SSRI…”
    Get full text
    Journal Article
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    Δ9-Tetrahydrocannabinol leads to endoplasmic reticulum stress and mitochondrial dysfunction in human BeWo trophoblasts by Lojpur, Tina, Easton, Zachary, Raez-Villanueva, Sergio, Laviolette, Steven, Holloway, Alison C., Hardy, Daniel B.

    Published in Reproductive toxicology (Elmsford, N.Y.) (01-08-2019)
    “…•Δ9-tetrahydrocannabinol directly induces endoplasmic stress in placental BeWo cells.•This helps elucidate why Δ9-tetrahydrocannabinol in vivo leads to…”
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    Impact of pesticide exposure on adipose tissue development and function by Gutgesell, Robert M, Tsakiridis, Evangelia E, Jamshed, Shanza, Steinberg, Gregory R, Holloway, Alison C

    Published in Biochemical journal (31-07-2020)
    “…Obesity is a leading cause of morbidity, mortality and health care expenditure whose incidence is rapidly rising across the globe. Although the cause of the…”
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    Journal Article
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    Excess feeding increases adipogenesis but lowers leptin transcript abundance in zebrafish larvae by Thompson, William Andrew, Rajeswari, Jithine Jayakumar, Holloway, Alison C, Vijayan, Mathilakath M

    “…Although fish exposed to municipal wastewater effluents (MWWE) show higher lipid accumulation, whether this is due to adipogenesis is unclear. The objective…”
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    Maternal exposure to Δ9-tetrahydrocannabinol impairs female offspring glucose homeostasis and endocrine pancreatic development in the rat by Gillies, Ryan, Lee, Kendrick, Vanin, Sebastian, Laviolette, Steven R., Holloway, Alison C., Arany, Edith, Hardy, Daniel B.

    Published in Reproductive toxicology (Elmsford, N.Y.) (01-06-2020)
    “…•Fetal exposure to Δ9-THC causes female-specific glucose intolerance in adulthood.•This glucose intolerance is associated with impaired insulin sensitivity in…”
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    Angiogenesis in the Placenta: The Role of Reactive Oxygen Species Signaling by Holloway, Alison C., Yazdi, Fereshteh T., Wang, Ruijun C., De Long, Nicole E., Pereira, Robyn D., Raha, Sandeep

    Published in BioMed research international (01-01-2015)
    “…Proper placental development and function are central to the health of both the mother and the fetus during pregnancy. A critical component of healthy…”
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    The effects of electronic cigarette vapor on placental trophoblast cell function by Raez-Villanueva, Sergio, Ma, Christina, Kleiboer, Sarah, Holloway, Alison C.

    Published in Reproductive toxicology (Elmsford, N.Y.) (01-10-2018)
    “…•E-cigarette use is increasing rapidly yet there is limited data available regarding its effects during pregnancy.•E-cigarette conditioned-media impaired…”
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    An Emerging Cross-Species Marker for Organismal Health: Tryptophan-Kynurenine Pathway by Jamshed, Laiba, Debnath, Amrita, Jamshed, Shanza, Wish, Jade V, Raine, Jason C, Tomy, Gregg T, Thomas, Philippe J, Holloway, Alison C

    “…Tryptophan (TRP) is an essential dietary amino acid that, unless otherwise committed to protein synthesis, undergoes metabolism via the Tryptophan-Kynurenine…”
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    Adverse fetal and neonatal outcomes associated with a life-long high fat diet: role of altered development of the placental vasculature by Hayes, Emily K, Lechowicz, Anna, Petrik, Jim J, Storozhuk, Yaryna, Paez-Parent, Sabrina, Dai, Qin, Samjoo, Imtiaz A, Mansell, Margaret, Gruslin, Andree, Holloway, Alison C, Raha, Sandeep

    Published in PloS one (19-03-2012)
    “…Maternal obesity results in a number of obstetrical and fetal complications with both immediate and long-term consequences. The increased prevalence of obesity…”
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    The role of the endocannabinoid system in female reproductive tissues by Walker, O'Llenecia S, Holloway, Alison C, Raha, Sandeep

    Published in Journal of ovarian research (15-01-2019)
    “…There has been increasing interest in the role of endocannabinoids as critical modulators of the female reproductive processes. Endocannabinoids are natural…”
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