Search Results - "Hollmann, Charleen"
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Altered lung biology of healthy never smokers following acute inhalation of E-cigarettes
Published in Respiratory research (14-05-2018)“…Little is known about health risks associated with electronic cigarette (EC) use although EC are rising in popularity and have been advocated as a means to…”
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2
Persistence of circulating endothelial microparticles in COPD despite smoking cessation
Published in Thorax (01-12-2016)“…Increasing evidence links COPD pathogenesis with pulmonary capillary apoptosis. We previously demonstrated that plasma levels of circulating microparticles…”
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3
Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation
Published in PloS one (17-04-2015)“…Even after quitting smoking, the risk of the development of chronic obstructive pulmonary disease (COPD) and lung cancer remains significantly higher compared…”
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4
Threshold of Biologic Responses of the Small Airway Epithelium to Low Levels of Tobacco Smoke
Published in American journal of respiratory and critical care medicine (15-12-2010)“…Epidemiologic data demonstrate that individuals exposed to low levels of tobacco smoke have decrements in lung function and higher risk for lung disease…”
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5
Intraflagellar transport gene expression associated with short cilia in smoking and COPD
Published in PloS one (20-01-2014)“…Smoking and COPD are associated with decreased mucociliary clearance, and healthy smokers have shorter cilia in the large airway than nonsmokers. We…”
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Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers
Published in American journal of respiratory and critical care medicine (01-09-2016)“…Waterpipes, also called hookahs, are currently used by millions of people worldwide. Despite the increasing use of waterpipe smoking, there is limited data on…”
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Prevalence of the Apolipoprotein E Arg145Cys Dyslipidemia At-Risk Polymorphism in African-Derived Populations
Published in The American journal of cardiology (15-01-2014)“…Apolipoprotein E, a protein component of blood lipid particles, plays an important role in lipid transport. Different mutations in the apolipoprotein E gene…”
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8
Calcium-Channel Blockers Preserve Coronary Endothelial Reactivity After Ischemia-Reperfusion
Published in The Annals of thoracic surgery (01-04-1997)“…Background. Calcium-channel blockers have been reported to improve myocardial recovery after ischemia-reperfusion, but their effects on coronary blood flow…”
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9
Long-term follow-up assessment of a phase 1 trial of angiogenic gene therapy using direct intramyocardial administration of an adenoviral vector expressing the VEGF121 cDNA for the treatment of diffuse coronary artery disease
Published in Human gene therapy (01-02-2013)“…On the basis of studies in experimental animals demonstrating that AdVEGF121, an E1(-)E3(-) serotype 5 adenovirus coding the 121 isoform of vascular…”
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10
Effects of University of Wisconsin solution on endothelium-dependent coronary artery relaxation in the rat
Published in The Annals of thoracic surgery (01-01-1993)“…University of Wisconsin (UW) solution has been reported to enhance myocardial preservation in heart transplantation. To evaluate the effects of UW solution on…”
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11
Beneficial effects of volatile anesthetics on decrease in coronary flow and myocardial contractility induced by oxygen-derived free radicals in isolated rabbit hearts
Published in Journal of cardiovascular pharmacology (01-12-1991)“…Oxygen-derived free radicals have been implicated in reperfusion injury whereas volatile anesthetics have been shown to enhance myocardial recovery during…”
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12
Prevalence of the ApoE Arg145Cys Dyslipidemia At-risk Polymorphism in African-derived Populations
Published in The American journal of cardiology (03-10-2013)“…Apolipoprotein E (ApoE), a protein component of blood lipid particles, plays an important role in lipid transport. Different mutations in the ApoE gene have…”
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13
Phase I/II study of intrapleural administration of a serotype rh.10 replication-deficient adeno-associated virus gene transfer vector expressing the human α1-antitrypsin cDNA to individuals with α1-antitrypsin deficiency
Published in Human gene therapy. Clinical development (01-09-2014)Get more information
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14
Differential degeneration of cortical thickness with disease progression in late infantile neuronal ceroid lipofuscinosis
Published in Molecular genetics and metabolism (01-02-2014)Get full text
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15
Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions
Published in Human gene therapy (01-01-2002)“…To help define the safety profile of the use of adenovirus (Ad) gene transfer vectors in humans, this report summarizes our experience since April 1993 of the…”
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16
Intraflagellar Transport Gene Expression Associated with Short Cilia in Smoking and COPD: e85453
Published in PloS one (01-01-2014)“…Smoking and COPD are associated with decreased mucociliary clearance, and healthy smokers have shorter cilia in the large airway than nonsmokers. We…”
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17
Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders
Published in Human gene therapy (01-09-2005)“…Genetic medicine-based therapies have unlocked the potential for ameliorating diseases previously considered inevitably fatal. Inherent in the clinical trials…”
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18
Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions
Published in Human gene therapy (01-01-2002)“…In this study we analyze the adverse events and abnormal laboratory parameters following local administration of low (<10(9) particle units) and intermediate…”
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19
Chronic exposure to cyclosporine affects endothelial and smooth muscle reactivity in the rat aorta
Published in The Annals of thoracic surgery (01-09-1994)“…Chronic exposure to cyclosporine affects vascular reactivity. Experiments were designed to characterize the endothelium-dependent and endothelium-independent…”
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20
Effects of pressure and duration of hyperkalemic infusions on endothelial function
Published in The Annals of thoracic surgery (01-03-1993)“…Infusions of crystalloid hyperkalemic cardioplegic solutions (CHCSs) are known to impair endotheliumdependent coronary relaxation. This impairment might also…”
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