Search Results - "Hollingsworth, Edward"

A thermostable L-aminoacylase from Thermococcus litoralis: cloning, overexpression, characterization, and applications in biotransformations by Toogood, Helen S, Hollingsworth, Edward J, Brown, Rob C, Taylor, Ian N, Taylor, Stephen J C, McCague, Ray, Littlechild, Jennifer A

“…A thermostable L-aminoacylase from Thermococcus litoralis was cloned, sequenced, and overexpressed in Escherichia coli. The enzyme is a homotetramer of 43 kDa…”
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Crystallization and preliminary X-ray diffraction studies of a fungal hydrolase from Ophiostoma novo-ulmi by Isupov, Michail N., Brindley, Amanda A., Hollingsworth, Edward J., Murshudov, Garib N., Vagin, Alexei A., Littlechild, Jennifer A.

“…Dutch elm disease fungus Ophiostoma novo‐ulmi contains a hydrolase activity which catalyses the resolution of racemic ethyl naproxen to the corresponding acid…”
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Crystallization and preliminary X-ray diffraction analysis of l-aminoacylase from the hyperthermophilic archaeon Thermococcus litoralis by Hollingsworth, Edward J., Isupov, Michail N., Littlechild, Jennifer A.

“…The enzyme l‐aminoacylase catalyses the hydrolysis of N‐acyl‐l‐­amino acids from peptides or proteins. The recombinant enzyme from the hyperthermophilic…”
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Development of an insect-cell-based assay for detection of kinase inhibition using NF-kappaB-inducing kinase as a paradigm by Hassan, Namir J, Gul, Sheraz, Flett, Fiona, Hollingsworth, Edward, Dunne, Angela A, Emmons, Amanda J, Hutchinson, Jonathan P, Hibbs, Martin J, Dyos, Susan, Kitson, Jeremy D, Hiley, Emma, Rüdiger, Martin, Tew, David G, Powell, David J, Morse, Mary A

“…Identification of small-molecule inhibitors by high-throughput screening necessitates the development of robust, reproducible and cost-effective assays. The…”
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Shot down over Frankfurt by Hollingsworth, Edward H

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