Search Results - "Holler, Edward R"

Multiple, reversible chlorination of C60 by Tebbe, Fred N, Becker, James Y, Chase, D. Bruce, Firment, Lawrence E, Holler, Edward R, Malone, Brian S, Krusic, Paul J, Wasserman, E

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Calculated and Experimental Low-Energy Conformations of Cyclic Urea HIV Protease Inhibitors by Hodge, C. Nicholas, Lam, Patrick Y. S, Eyermann, Charles J, Jadhav, Prabhakar K, Ru, Y, Fernandez, Christina H, De Lucca, George V, Chang, Chong-Hwan, Kaltenbach, Robert F, Holler, Edward R, Woerner, Francis, Daneker, Wayne F, Emmett, George, Calabrese, Joseph C, Aldrich, Paul E

“…One important factor influencing the affinity of a flexible ligand for a receptor is the internal strain energy required to attain the bound conformation…”
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Improved P1/P1‘ Substituents for Cyclic Urea Based HIV-1 Protease Inhibitors:  Synthesis, Structure−Activity Relationship, and X-ray Crystal Structure Analysis by Nugiel, David A, Jacobs, Kim, Cornelius, Lyndon, Chang, Chong-Hwan, Jadhav, Prabhakar K, Holler, Edward R, Klabe, Ronald M, Bacheler, Lee T, Cordova, Beverly, Garber, Sena, Reid, Carol, Logue, Kelly A, Gorey-Feret, Lorraine J, Lam, Gilbert N, Erickson-Viitanen, Susan, Seitz, Steven P

“…We present several novel P1/P1‘ substituents that can replace the characteristic benzyl P1/P1‘ moiety of the cyclic urea based HIV protease inhibitor series…”
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Cyclic HIV Protease Inhibitors:  Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas by Lam, Patrick Y. S, Ru, Yu, Jadhav, Prabhakar K, Aldrich, Paul E, DeLucca, George V, Eyermann, Charles J, Chang, Chong-Hwan, Emmett, George, Holler, Edward R, Daneker, Wayne F, Li, Liangzhu, Confalone, Pat N, McHugh, Robert J, Han, Qi, Li, Renhua, Markwalder, Jay A, Seitz, Steven P, Sharpe, Thomas R, Bacheler, Lee T, Rayner, Marlene M, Klabe, Ronald M, Shum, Linyee, Winslow, Dean L, Kornhauser, David M, Jackson, David A, Erickson-Viitanen, Susan, Hodge, C. Nicholas

“…High-resolution X-ray structures of the complexes of HIV-1 protease (HIV-1PR) with peptidomimetic inhibitors reveal the presence of a structural water molecule…”
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