Search Results - "Hollensen, Anne K."

Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic by Duncan, Christopher J A, Skouboe, Morten K, Howarth, Sophie, Hollensen, Anne K, Chen, Rui, Børresen, Malene L, Thompson, Benjamin J, Stremenova Spegarova, Jarmila, Hatton, Catherine F, Stæger, Frederik F, Andersen, Mette K, Whittaker, John, Paludan, Søren R, Jørgensen, Sofie E, Thomsen, Martin K, Mikkelsen, Jacob G, Heilmann, Carsten, Buhas, Daniela, Øbro, Nina F, Bay, Jakob T, Marquart, Hanne V, de la Morena, M Teresa, Klejka, Joseph A, Hirschfeld, Matthew, Borgwardt, Line, Forss, Isabel, Masmas, Tania, Poulsen, Anja, Noya, Francisco, Rouleau, Guy, Hansen, Torben, Zhou, Sirui, Albrechtsen, Anders, Alizadehfar, Reza, Allenspach, Eric J, Hambleton, Sophie, Mogensen, Trine H

“…Type I interferons (IFN-I) play a critical role in human antiviral immunity, as demonstrated by the exceptionally rare deleterious variants of IFNAR1 or…”
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Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming by Olagnier, David, Brandtoft, Aske M., Gunderstofte, Camilla, Villadsen, Nikolaj L., Krapp, Christian, Thielke, Anne L., Laustsen, Anders, Peri, Suraj, Hansen, Anne Louise, Bonefeld, Lene, Thyrsted, Jacob, Bruun, Victor, Iversen, Marie B., Lin, Lin, Artegoitia, Virginia M., Su, Chenhe, Yang, Long, Lin, Rongtuan, Balachandran, Siddharth, Luo, Yonglun, Nyegaard, Mette, Marrero, Bernadette, Goldbach-Mansky, Raphaela, Motwani, Mona, Ryan, Dylan G., Fitzgerald, Katherine A., O’Neill, Luke A., Hollensen, Anne K., Damgaard, Christian K., de Paoli, Frank v., Bertram, Hanne C., Jakobsen, Martin R., Poulsen, Thomas B., Holm, Christian K.

“…The transcription factor Nrf2 is a critical regulator of inflammatory responses. If and how Nrf2 also affects cytosolic nucleic acid sensing is currently…”
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mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1 by Jia, Jian-Jun, Lahr, Roni M, Solgaard, Michael T, Moraes, Bruno J, Pointet, Roberta, Yang, An-Dao, Celucci, Giovanna, Graber, Tyson E, Hoang, Huy-Dung, Niklaus, Marius R, Pena, Izabella A, Hollensen, Anne K, Smith, Ewan M, Chaker-Margot, Malik, Anton, Leonie, Dajadian, Christopher, Livingstone, Mark, Hearnden, Jaclyn, Wang, Xu-Dong, Yu, Yonghao, Maier, Timm, Damgaard, Christian K, Berman, Andrea J, Alain, Tommy, Fonseca, Bruno D

“…Abstract LARP1 is a key repressor of TOP mRNA translation. It binds the m7Gppp cap moiety and the adjacent 5′TOP motif of TOP mRNAs, thus impeding the assembly…”
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