Search Results - "Hollenberg, Norman K"
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Cocoa and Cardiovascular Health
Published in Circulation (New York, N.Y.) (17-03-2009)“…Epidemiological data demonstrate that regular dietary intake of plant-derived foods and beverages reduces the risk of coronary heart disease and stroke. Among…”
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Aldosterone in the development and progression of renal injury
Published in Kidney international (01-07-2004)“…Aldosterone in the development and progression of renal injury. The renin-angiotensin-aldosterone system (RAAS) contributes to hypertension and nephropathy…”
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(--)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans
Published in Proceedings of the National Academy of Sciences - PNAS (24-01-2006)“…Epidemiological and medical anthropological investigations suggest that flavanol-rich foods exert cardiovascular health benefits. Endothelial dysfunction, a…”
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Aliskiren in Combination with Losartan Reduces Albuminuria Independent of Baseline Blood Pressure in Patients with Type 2 Diabetes and Nephropathy
Published in Clinical journal of the American Society of Nephrology (01-05-2011)“…Elevated BP contributes to development and progression of proteinuria and decline in renal function in patients with type 2 diabetes. Our post hoc analysis…”
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Vascular Action of Cocoa Flavanols in Humans: The Roots of the Story
Published in Journal of cardiovascular pharmacology (01-06-2006)“…Diet patterns are widely recognized as contributors to hypertension. Widely studied potential contributors include intake of sodium, potassium, magnesium,…”
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Urinary Potassium Excretion and Sodium Sensitivity in Blacks
Published in Hypertension (Dallas, Tex. 1979) (01-04-2004)“…ABSTRACT—Based on racial differences in urinary potassium excretion and responses to diuretics, we present a model suggesting that a major cause of sodium…”
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Cerebral blood flow response to flavanol-rich cocoa in healthy elderly humans
Published in Neuropsychiatric disease and treatment (01-04-2008)“…Cerebral ischemia is a common, morbid condition accompanied by cognitive decline. Recent reports on the vascular health benefits of flavanol-containing foods…”
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Uric acid and the state of the intrarenal renin-angiotensin system in humans
Published in Kidney international (01-10-2004)“…Uric acid and the state of the intrarenal renin-angiotensin system in humans. Experimental hyperuricemia is marked by an activated intrarenal renin-angiotensin…”
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Hypertension, the Kuna, and the Epidemiology of Flavanols
Published in Journal of cardiovascular pharmacology (01-06-2006)“…A low sodium diet has often been implicated in the protection of low blood pressure populations from hypertension, but several other dietary factors, including…”
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10
Aliskiren Accumulates in Renin Secretory Granules and Binds Plasma Prorenin
Published in Hypertension (Dallas, Tex. 1979) (01-12-2008)“…The vascular effects of aliskiren last longer than expected based on its half life, and this renin inhibitor has been reported to cause a greater renin rise…”
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Body Mass Index and Angiotensin-Dependent Control of the Renal Circulation in Healthy Humans
Published in Hypertension (Dallas, Tex. 1979) (01-12-2005)“…Obesity is increasingly recognized as a risk factor for renal disease, but the mechanism is unclear. Renal plasma flow response to captopril, as an index of…”
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Evaluation of a direct prorenin assay making use of a monoclonal antibody directed against residues 32-39 of the prosegment
Published in Journal of hypertension (01-11-2011)“…Prorenin is an early marker of microvascular complications in diabetes. However, it can only be measured indirectly (following its conversion to renin), with a…”
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13
Aliskiren Combined with Losartan in Type 2 Diabetes and Nephropathy
Published in The New England journal of medicine (05-06-2008)“…In this study, patients with type 2 diabetes and nephropathy received either aliskiren, an oral direct renin inhibitor, or placebo, in addition to the maximal…”
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Insulin induces renal vasodilation, increases plasma renin activity, and sensitizes the renal vasculature to angiotensin receptor blockade in healthy subjects
Published in Journal of the American Society of Nephrology (01-03-2007)“…Insulin stimulates the renin-angiotensin system and induces renal vasodilation. The relationship between these opposing influences of insulin on renal vascular…”
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Oral Contraceptives, Angiotensin-Dependent Renal Vasoconstriction, and Risk of Diabetic Nephropathy
Published in Diabetes care (01-08-2005)“…OBJECTIVE:--Diabetes, the leading cause of end-stage renal disease in the U.S., is believed to involve activation of the renin angiotensin system (RAS) as a…”
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Gender and the Renal Nitric Oxide Synthase System in Healthy Humans
Published in Clinical journal of the American Society of Nephrology (01-09-2007)“…It is widely known that men with kidney disease progress to ESRD at a much greater rate than do women. The mechanism for these gender differences is not clear,…”
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Aging, Acculturation, Salt Intake, and Hypertension in the Kuna of Panama
Published in Hypertension (Dallas, Tex. 1979) (01-01-1997)“…The indigenous Kuna who live on islands in the Panamanian Caribbean were among the first communities described with little age-related rise in blood pressure…”
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Renin Inhibition: What Are the Clinical Perspectives?
Published in Seminars in nephrology (01-09-2007)“…Summary Evidence that renin system blockade is useful in many patients with hypertension is overwhelming. Two recent lines of investigation have suggested that…”
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Renin inhibition with aliskiren : where are we now, and where are we going?
Published in Journal of hypertension (01-02-2006)“…With the development of aliskiren, blockade of the renin-angiotensin-aldosterone system (RAAS) at the level of the interaction of renin with a substrate has…”
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Direct renin inhibition and the kidney
Published in Nature reviews. Nephrology (01-01-2010)“…Direct renin inhibition is a novel strategy for the blockade of the renin–angiotensin system. In this Review, Hollenberg discusses the evidence indicating that…”
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