Search Results - "Hollander, Jonathan A."
-
1
Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area
Published in Proceedings of the National Academy of Sciences - PNAS (22-04-2014)“…Hypocretin (orexin) and dynorphin are neuropeptides with opposing actions on motivated behavior. Orexin is implicated in states of arousal and reward, whereas…”
Get full text
Journal Article -
2
Insular hypocretin transmission regulates nicotine reward
Published in Proceedings of the National Academy of Sciences - PNAS (09-12-2008)“…Damage to the insular cortex can profoundly disrupt tobacco addiction in human smokers, reflected in spontaneous cessation of the tobacco habit and…”
Get full text
Journal Article -
3
Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2020)“…The etiologic pathways leading to neuropsychiatric diseases remain poorly defined. As genomic technologies have advanced over the past several decades,…”
Get full text
Journal Article -
4
Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence
Published in Frontiers in behavioral neuroscience (2012)“…Considerable evidence suggests that transmission at hypocretin-1 (orexin-1) receptors (Hcrt-R1) plays an important role in the reinstatement of extinguished…”
Get full text
Journal Article -
5
Abstinence from Cocaine Self-Administration Heightens Neural Encoding of Goal-Directed Behaviors in the Accumbens
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2005)“…Cocaine addiction in humans is characterized by cycles of abstinence from drug-taking and relapse. Here, electrophysiological recording procedures were used to…”
Get full text
Journal Article -
6
MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212
Published in Nature neuroscience (01-09-2010)“…The authors implicate the transcriptional repressor methyl CpG–binding protein MeCP2 in cocaine addiction. They report that MeCP2 regulates cocaine intake…”
Get full text
Journal Article -
7
Striatal microRNA controls cocaine intake through CREB signalling
Published in Nature (London) (08-07-2010)“…Cocaine addiction is characterized by a gradual loss of control over drug use, but the molecular mechanisms regulating vulnerability to this process remain…”
Get full text
Journal Article -
8
Cocaine-Associated Stimuli Increase Cocaine Seeking and Activate Accumbens Core Neurons after Abstinence
Published in The Journal of neuroscience (28-03-2007)“…Electrophysiological recordings were completed in rats (n = 14) trained to self-administer cocaine to determine whether activation of nucleus accumbens (Acb)…”
Get full text
Journal Article -
9
Seminar: Extracellular Vesicles as Mediators of Environmental Stress in Human Disease
Published in Environmental health perspectives (01-10-2023)“…Extracellular vesicles (EVs), membrane-bound particles containing a variety of RNA types, DNA, proteins, and other macromolecules, are now appreciated as an…”
Get full text
Journal Article -
10
2021 Workshop: Neurodegenerative Diseases in the Gut-Brain Axis—Parkinson's Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2022)Get full text
Journal Article -
11
Decreased brain reward function during nicotine withdrawal in C57BL6 mice: Evidence from intracranial self-stimulation (ICSS) studies
Published in Pharmacology, biochemistry and behavior (01-09-2008)“…Deficits in brain reward function during nicotine withdrawal may serve as an important substrate for negative reinforcement that contributes to the persistence…”
Get full text
Journal Article -
12
Basolateral Amygdala Neurons Encode Cocaine Self-Administration and Cocaine-Associated Cues
Published in The Journal of neuroscience (10-09-2003)“…Electrophysiological recording procedures were used to examine basolateral amygdala (BLA) cell firing during cocaine self-administration and relative to…”
Get full text
Journal Article -
13
An examination of nucleus accumbens cell firing during extinction and reinstatement of water reinforcement behavior in rats
Published in Brain research (08-03-2002)“…Electrophysiological recording procedures were used to examine nucleus accumbens (Acb) cell firing in rats ( n=13) during water reinforcement sessions…”
Get full text
Journal Article -
14
Accumbens activity during a multiple schedule for water and sucrose reinforcement in rats
Published in Synapse (New York, N.Y.) (15-03-2002)“…Electrophysiological recording procedures were used to examine nucleus accumbens (Acb) cell firing during operant responding for water reinforcement vs. a…”
Get full text
Journal Article -
15