Search Results - "Holland, Peter"

Reconstruction of the ancestral metazoan genome reveals an increase in genomic novelty by Paps, Jordi, Holland, Peter W. H.

“…Understanding the emergence of the Animal Kingdom is one of the major challenges of modern evolutionary biology. Many genomic changes took place along the…”
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New genes from old: asymmetric divergence of gene duplicates and the evolution of development by Holland, Peter W. H., Marlétaz, Ferdinand, Maeso, Ignacio, Dunwell, Thomas L., Paps, Jordi

“…Gene duplications and gene losses have been frequent events in the evolution of animal genomes, with the balance between these two dynamic processes…”
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Employee Voice, Supervisor Support, and Engagement: The Mediating Role of Trust by Holland, Peter, Cooper, Brian, Sheehan, Cathy

“…Developing employee engagement has been one of the major areas of interest in the field of human resource management (HRM), and research identifies the…”
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A single three-dimensional chromatin compartment in amphioxus indicates a stepwise evolution of vertebrate Hox bimodal regulation by Acemel, Rafael D, Tena, Juan J, Irastorza-Azcarate, Ibai, Marlétaz, Ferdinand, Gómez-Marín, Carlos, de la Calle-Mustienes, Elisa, Bertrand, Stéphanie, Diaz, Sergio G, Aldea, Daniel, Aury, Jean-Marc, Mangenot, Sophie, Holland, Peter W H, Devos, Damien P, Maeso, Ignacio, Escrivá, Hector, Gómez-Skarmeta, José Luis

“…José Luis Gómez-Skarmeta, Hector Escrivá, Ignacio Maeso, Damien Devos and colleagues perform 4C-seq profiling of the Hox cluster in amphioxus embryos and find…”
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GC Content Across Insect Genomes: Phylogenetic Patterns, Causes and Consequences by Kyriacou, Riccardo G., Mulhair, Peter O., Holland, Peter W. H.

“…The proportions of A:T and G:C nucleotide pairs are often unequal and can vary greatly between animal species and along chromosomes. The causes and…”
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Lineage-specific rediploidization is a mechanism to explain time-lags between genome duplication and evolutionary diversification by Robertson, Fiona M, Gundappa, Manu Kumar, Grammes, Fabian, Hvidsten, Torgeir R, Redmond, Anthony K, Lien, Sigbjørn, Martin, Samuel A M, Holland, Peter W H, Sandve, Simen R, Macqueen, Daniel J

“…The functional divergence of duplicate genes (ohnologues) retained from whole genome duplication (WGD) is thought to promote evolutionary diversification…”
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Evolution of homeobox genes by Holland, Peter W H

“…Many homeobox genes encode transcription factors with regulatory roles in animal and plant development. Homeobox genes are found in almost all eukaryotes, and…”
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Classification and nomenclature of all human homeobox genes by Holland, Peter W H, Booth, H Anne F, Bruford, Elspeth A

“…The homeobox genes are a large and diverse group of genes, many of which play important roles in the embryonic development of animals. Increasingly, homeobox…”
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Evolution of the insect Hox gene cluster: Comparative analysis across 243 species by Mulhair, Peter O, Holland, Peter W H

“…The Hox gene cluster is an iconic example of evolutionary conservation between divergent animal lineages, providing evidence for ancient similarities in the…”
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PRD-Class Homeobox Genes in Bovine Early Embryos: Function, Evolution, and Overlapping Roles by Lewin, Thomas D., Fouladi-Nashta, Ali A., Holland, Peter W.H.

“…Abstract Eutherian Totipotent Cell Homeobox (ETCHbox) genes are mammalian-specific PRD-class homeobox genes with conserved expression in the preimplantation…”
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Occasion Setting by Fraser, Kurt M, Holland, Peter C

“…Occasion setting refers to the ability of 1 stimulus, an occasion setter, to modulate the efficacy of the association between another, conditioned stimulus…”
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Jellyfish genomes reveal distinct homeobox gene clusters and conservation of small RNA processing by Nong, Wenyan, Cao, Jianquan, Li, Yiqian, Qu, Zhe, Sun, Jin, Swale, Thomas, Yip, Ho Yin, Qian, Pei Yuan, Qiu, Jian-Wen, Kwan, Hoi Shan, Bendena, William, Tobe, Stephen, Chan, Ting Fung, Yip, Kevin Y., Chu, Ka Hou, Ngai, Sai Ming, Tsim, Karl Yk, Holland, Peter W. H., Hui, Jerome H. L.

“…The phylum Cnidaria represents a close outgroup to Bilateria and includes familiar animals including sea anemones, corals, hydroids, and jellyfish. Here we…”
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Dynamic Molecular Evolution of Mammalian Homeobox Genes: Duplication, Loss, Divergence and Gene Conversion Sculpt PRD Class Repertoires by Lewin, Thomas D., Royall, Amy H., Holland, Peter W. H.

“…The majority of homeobox genes are highly conserved across animals, but the eutherian-specific ETCHbox genes, embryonically expressed and highly divergent…”
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The impact of technology on work in the twenty-first century: exploring the smart and dark side by Holland, Peter, Bardoel, Anne

“…The twenty-first century has seen significant expansion in the use and availability of technology, which has created a paradigm shift in how we can work. The…”
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Evidence from oyster suggests an ancient role for Pdx in regulating insulin gene expression in animals by Xu, Fei, Marlétaz, Ferdinand, Gavriouchkina, Daria, Liu, Xiao, Sauka-Spengler, Tatjana, Zhang, Guofan, Holland, Peter W. H.

“…Hox and ParaHox genes encode transcription factors with similar expression patterns in divergent animals. The Pdx ( Xlox ) homeobox gene, for example, is…”
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Divergent genes in gerbils: prevalence, relation to GC-biased substitution, and phenotypic relevance by Dai, Yichen, Pracana, Rodrigo, Holland, Peter W H

“…Two gerbil species, sand rat (Psammomys obesus) and Mongolian jird (Meriones unguiculatus), can become obese and show signs of metabolic dysregulation when…”
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Ancient expansion of the hox cluster in lepidoptera generated four homeobox genes implicated in extra-embryonic tissue formation by Ferguson, Laura, Marlétaz, Ferdinand, Carter, Jean-Michel, Taylor, William R, Gibbs, Melanie, Breuker, Casper J, Holland, Peter W H

“…Gene duplications within the conserved Hox cluster are rare in animal evolution, but in Lepidoptera an array of divergent Hox-related genes (Shx genes) has…”
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The Interaction of Natural Selection and GC Skew May Drive the Fast Evolution of a Sand Rat Homeobox Gene by Dai, Yichen, Holland, Peter W H

“…Several processes can lead to strong GC skew in localized genomic regions. In most cases, GC skew should not affect conserved amino acids because natural…”
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Scenarios for the making of vertebrates by Holland, Nicholas D., Holland, Linda Z., Holland, Peter W. H.

“…Over the past 200 years, almost every invertebrate phylum has been proposed as a starting point for evolving vertebrates. Most of these scenarios are outdated,…”
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Widespread patterns of gene loss in the evolution of the animal kingdom by Guijarro-Clarke, Cristina, Holland, Peter W. H., Paps, Jordi

“…The animal kingdom shows an astonishing diversity, the product of over 550 million years of animal evolution. The current wealth of genome sequence data offers…”
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