Search Results - "Holland, Lisa"

Profiling the N‑Glycan Composition of IgG with Lectins and Capillary Nanogel Electrophoresis by Lu, Grace, Holland, Lisa A

“…Glycosylated human IgG contains fucosylated biantennary N-glycans with different modifications including N-acetylglucosamine, which bisects the mannose core…”
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Capillary Electrophoresis Separations of Glycans by Lu, Grace, Crihfield, Cassandra L, Gattu, Srikanth, Veltri, Lindsay M, Holland, Lisa A

“…Capillary electrophoresis has emerged as a powerful approach for carbohydrate analyses since 2014. The method provides high resolution capable of separating…”
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Capillary Nanogel Electrophoresis for the Determination of the β1–4 Galactosyltransferase Michaelis–Menten Constant and Real-Time Addition of Galactose Residues to N‑Glycans and Glycoprotein by Bwanali, Lloyd, Holland, Lisa A

“…A thermally reversible nanogel is used in capillary electrophoresis to create discrete regions for a galactosyltransferase reaction and separation. The β1–4…”
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Fluorescent parallel electrophoresis assay of enzyme inhibition by Casto-Boggess, Laura D., Holland, Lisa A.

“…Enzyme inhibitors comprise the largest class of pharmaceutical compounds. The discovery and development of new enzyme inhibitor drug candidates depends on…”
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Nanoparticle–Protein Interactions: A Thermodynamic and Kinetic Study of the Adsorption of Bovine Serum Albumin to Gold Nanoparticle Surfaces by Boulos, Stefano P, Davis, Tyler A, Yang, Jie An, Lohse, Samuel E, Alkilany, Alaaldin M, Holland, Lisa A, Murphy, Catherine J

“…Investigating the adsorption process of proteins on nanoparticle surfaces is essential to understand how to control the biological interactions of…”
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Protein Sieving with Capillary Nanogel Electrophoresis by Crihfield, Cassandra L, Holland, Lisa A

“…Protein sieving, which is a fundamental tool in the biotechnology field, can be automated using capillary gel electrophoresis. The high-viscosity and…”
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Low Flow Voltage Free Interface for Capillary Electrophoresis and Mass Spectrometry Driven by Vibrating Sharp-Edge Spray Ionization by Kristoff, Courtney J, Li, Chong, Li, Peng, Holland, Lisa A

“…Capillary electrophoresis-mass spectrometry is a powerful technique for high-throughput and high efficiency separations combined with structural…”
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Capillary electrophoresis applied to DNA: determining and harnessing sequence and structure to advance bioanalyses (2009–2014) by Durney, Brandon C, Crihfield, Cassandra L, Holland, Lisa A

“…This review of capillary electrophoresis methods for DNA analyses covers critical advances from 2009 to 2014, referencing 184 citations. Separation mechanisms…”
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Challenging Bioanalyses with Capillary Electrophoresis by Kristoff, Courtney J, Bwanali, Lloyd, Veltri, Lindsay M, Gautam, Gayatri P, Rutto, Patrick K, Newton, Ebenezer O, Holland, Lisa A

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In vitro selection of a single-stranded DNA molecular recognition element against atrazine by Williams, Ryan M, Crihfield, Cassandra L, Gattu, Srikanth, Holland, Lisa A, Sooter, Letha J

“…Widespread use of the chlorotriazine herbicide, atrazine, has led to serious environmental and human health consequences. Current methods of detecting atrazine…”
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Fibroblast Growth Factor-23 and Risks of Cardiovascular and Noncardiovascular Diseases: A Meta-Analysis by Marthi, Amarnath, Donovan, Killian, Haynes, Richard, Wheeler, David C, Baigent, Colin, Rooney, Christopher M, Landray, Martin J, Moe, Sharon M, Yang, Jun, Holland, Lisa, di Giuseppe, Romina, Bouma-de Krijger, Annet, Mihaylova, Borislava, Herrington, William G

“…Fibroblast growth factor-23 (FGF-23) has been hypothesized to play a role in the increased risk of cardiovascular disease in patients with CKD. We identified…”
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Gels in Microscale Electrophoresis by Holland, Lisa A, Casto-Boggess, Laura D

“…Gel matrices are fundamental to electrophoresis analyses of biopolymers in microscale channels. Both capillary gel and microchannel gel electrophoresis systems…”
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Microscale Measurements of Michaelis–Menten Constants of Neuraminidase with Nanogel Capillary Electrophoresis for the Determination of the Sialic Acid Linkage by Gattu, Srikanth, Crihfield, Cassandra. L, Holland, Lisa A

“…Phospholipid nanogels enhance the stability and performance of the exoglycosidase enzyme neuraminidase and are used to create a fixed zone of enzyme within a…”
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Advances in enzyme substrate analysis with capillary electrophoresis by Gattu, Srikanth, Crihfield, Cassandra L., Lu, Grace, Bwanali, Lloyd, Veltri, Lindsay M., Holland, Lisa A.

“…•A separation-based assay enables detection of product in the presence of substrate.•Capillary electrophoresis is suitable for analysis of enzyme in limited…”
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Simple, rapid, and reproducible capillary gel electrophoresis separation and laser-induced fluorescence detection of DNA topoisomers with unmodified fused silica separation capillaries by Holland, Lisa A., He, Yan, Guerrette, Jessica R., Crihfield, Cassandra L., Bwanali, Lloyd

“…The topology of DNA is a critical quality attribute for plasmid-based pharmaceuticals, making quantification of trace levels of plasmid topoisomers an…”
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Microscale Quantification of the Inhibition of Neuraminidase Using Capillary Nanogel Electrophoresis by Casto-Boggess, Laura D., Holland, Lisa A., Lawer-Yolar, Paul A., Lucas, John A., Guerrette, Jessica R.

“…Neuraminidase inhibitors modulate infections that involve sialic acids, making quantitative analyses of this inhibitory effect important for selecting and…”
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Microfluidics for Personalized Reactions to Demonstrate Stoichiometry by Veltri, Lindsay M, Holland, Lisa A

“…Stoichiometry, the ideal gas law, and the concept of limiting reagent are challenging principles for students to conceptualize in introductory chemistry. These…”
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Peptide Probe for Multiwalled Carbon Nanotubes: Electrophoretic Assessment of the Binding Interface and Evaluation of Surface Functionalization by Davis, Tyler A, Holland, Lisa A

“…Noncovalent interactions of peptides and proteins with carbon nanotubes play a key role in sensing, dispersion, and biocompatibility. Advances in these areas…”
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Quantification of the α2–6 Sialic Acid Linkage in Branched N‑Glycan Structures with Capillary Nanogel Electrophoresis by Bwanali, Lloyd, Crihfield, Cassandra L, Newton, Ebenezer O, Zeger, Victoria R, Gattu, Srikanth, Holland, Lisa A

“…Sialylation and sialic acid linkage in N-glycans are markers of disease but are analytically challenging to quantify. A capillary electrophoresis method is…”
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A Unique Set of the Burkholderia Collagen-Like Proteins Provides Insight into Pathogenesis, Genome Evolution and Niche Adaptation, and Infection Detection by Bachert, Beth A, Choi, Soo J, Snyder, Anna K, Rio, Rita V M, Durney, Brandon C, Holland, Lisa A, Amemiya, Kei, Welkos, Susan L, Bozue, Joel A, Cote, Christopher K, Berisio, Rita, Lukomski, Slawomir

“…Burkholderia pseudomallei and Burkholderia mallei, classified as category B priority pathogens, are significant human and animal pathogens that are highly…”
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