Search Results - "Holland, Carolyn A"

Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya by Ogutu, Bernhards R, Apollo, Odika J, McKinney, Denise, Okoth, Willis, Siangla, Joram, Dubovsky, Filip, Tucker, Kathryn, Waitumbi, John N, Diggs, Carter, Wittes, Janet, Malkin, Elissa, Leach, Amanda, Soisson, Lorraine A, Milman, Jessica B, Otieno, Lucas, Holland, Carolyn A, Polhemus, Mark, Remich, Shon A, Ockenhouse, Christian F, Cohen, Joe, Ballou, W Ripley, Martin, Samuel K, Angov, Evelina, Stewart, V Ann, Lyon, Jeffrey A, Heppner, D Gray, Withers, Mark R

“…The antigen, falciparum malaria protein 1 (FMP1), represents the 42-kDa C-terminal fragment of merozoite surface protein-1 (MSP-1) of the 3D7 clone of P…”
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Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naïve adults at the Walter Reed Army Institute of Research by Kester, Kent E, Cummings, James F, Ockenhouse, Christian F, Nielsen, Robin, Hall, B. Ted, Gordon, Daniel M, Schwenk, Robert J, Krzych, Urszula, Holland, Carolyn A, Richmond, Gregory, Dowler, Megan G, Williams, Jackie, Wirtz, Robert A, Tornieporth, Nadia, Vigneron, Laurence, Delchambre, Martine, Demoitie, Marie-Ange, Ballou, W. Ripley, Cohen, Joe, Heppner, D. Gray

“…Summary Background Immunization with RTS,S/AS02 consistently protects some vaccinees against malaria infection in experimental challenges and in field trials…”
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Phase 1 randomized double-blind safety and immunogenicity trial of Plasmodium falciparum malaria merozoite surface protein FMP1 vaccine, adjuvanted with AS02A, in adults in western Kenya by Stoute, José A, Gombe, Joash, Withers, Mark R, Siangla, Joram, McKinney, Denise, Onyango, Melanie, Cummings, James F, Milman, Jessica, Tucker, Kathryn, Soisson, Lorraine, Stewart, V. Ann, Lyon, Jeffrey A, Angov, Evelina, Leach, Amanda, Cohen, Joe, Kester, Kent E, Ockenhouse, Christian F, Holland, Carolyn A, Diggs, Carter L, Wittes, Janet, Gray Heppner, D

“…Abstract We report the first trial of candidate malaria vaccine antigen FMP1, a 42 kDa fragment from the C-terminus of merozoite surface protein-1 (MSP-1) from…”
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Heterologous prime-boost immunization in rhesus macaques by two, optimally spaced particle-mediated epidermal deliveries of Plasmodium falciparum circumsporozoite protein-encoding DNA, followed by intramuscular RTS,S/AS02A by Walsh, Douglas S., Gettayacamin, Montip, Leitner, Wolfgang W., Lyon, Jeffrey A., Stewart, V. Ann, Marit, Gary, Pichyangkul, Sathit, Gosi, Panita, Tongtawe, Pongsri, Kester, Kent E., Holland, Carolyn A., Kolodny, Nelly, Cohen, Joe, Voss, Gerald, Ballou, W. Ripley, Heppner, D. Gray

“…RTS,S/AS02A, a recombinant Plasmodium falciparum vaccine based on the circumsporozoite protein (CSP) repeat and C-terminus regions, elicits strong humoral and…”
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Safety and reactogenicity of an MSP-1 malaria vaccine candidate: a randomized phase Ib dose-escalation trial in Kenyan children by Withers, Mark R, McKinney, Denise, Ogutu, Bernhards R, Waitumbi, John N, Milman, Jessica B, Apollo, Odika J, Allen, Otieno G, Tucker, Kathryn, Soisson, Lorraine A, Diggs, Carter, Leach, Amanda, Wittes, Janet, Dubovsky, Filip, Stewart, V Ann, Remich, Shon A, Cohen, Joe, Ballou, W Ripley, Holland, Carolyn A, Lyon, Jeffrey A, Angov, Evelina, Stoute, José A, Martin, Samuel K, Heppner, Jr, D Gray

“…Our aim was to evaluate the safety, reactogenicity, and immunogenicity of an investigational malaria vaccine. This was an age-stratified phase Ib,…”
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Safety and immunogenicity of rts,s+trap malaria vaccine, formulated in the as02a adjuvant system, in infant rhesus monkeys by Walsh, Douglas S, Pichyangkul, Sathit, Gettayacamin, Montip, Tongtawe, Pongsri, Siegrist, Claire-Anne, Hansukjariya, Pranee, Kester, Kent E, Holland, Carolyn A, Voss, Gerald, Cohen, Joe, Stewart, Ann V, Miller, R Scott, Ballou, W Ripley, Heppner, Jr, D Gray

“…Malaria vaccine RTS,S combined with thrombospondin-related anonymous protein (TRAP) and formulated with AS02A (RTS,S+TRAP/AS02A) is safe and immunogenic in…”
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Heterologous prime-boost immunization in rhesus macaques by two, optimally spaced particle-mediated epidermal deliveries ofPlasmodium falciparumcircumsporozoite protein-encoding DNA, followed by intramuscular RTS,S/AS02A by Walsh, Douglas S, Gettayacamin, Montip, Leitner, Wolfgang W, Lyon, Jeffrey A, Stewart, V Ann, Marit, Gary, Pichyangkul, Sathit, Gosi, Panita, Tongtawe, Pongsri, Kester, Kent E, Holland, Carolyn A, Kolodny, Nelly, Cohen, Joe, Voss, Gerald, Ballou, W Ripley, Heppner, D Gray

“…Background RTS,S/AS02A, a recombinantPlasmodium falciparumvaccine based on the circumsporozoite protein (CSP) repeat and C-terminus regions, elicits strong…”
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Phase 1 randomized double-blind safety and immunogenicity trial ofPlasmodium falciparummalaria merozoite surface protein FMP1 vaccine, adjuvanted with AS02A, in adults in western Kenya by Stoute, José A, Gombe, Joash, Withers, Mark R, Siangla, Joram, McKinney, Denise, Onyango, Melanie, Cummings, James F, Milman, Jessica, Tucker, Kathryn, Soisson, Lorraine, Stewart, V Ann, Lyon, Jeffrey A, Angov, Evelina, Leach, Amanda, Cohen, Joe, Kester, Kent E, Ockenhouse, Christian F, Holland, Carolyn A, Diggs, Carter L, Wittes, Janet, Gray Heppner, D

“…We report the first trial of candidate malaria vaccine antigen FMP1, a 42kDa fragment from the C-terminus of merozoite surface protein-1 (MSP-1) from the 3D7…”
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