Search Results - "Holland, C. M."

Standardizing terms, definitions and concepts for describing and interpreting unwanted immunogenicity of biopharmaceuticals: recommendations of the Innovative Medicines Initiative ABIRISK consortium by Rup, B., Pallardy, M., Sikkema, D., Albert, T., Allez, M., Broet, P., Carini, C., Creeke, P., Davidson, J., De Vries, N., Finco, D., Fogdell‐Hahn, A., Havrdova, E., Hincelin‐Mery, A., C. Holland, M., H. Jensen, P. E., Jury, E. C., Kirby, H., Kramer, D., Lacroix‐Desmazes, S., Legrand, J., Maggi, E., Maillère, B., Mariette, X., Mauri, C., Mikol, V., Mulleman, D., Oldenburg, J., Paintaud, G., R. Pedersen, C., Ruperto, N., Seitz, R., Spindeldreher, S., Deisenhammer, F.

“…Summary Biopharmaceuticals (BPs) represent a rapidly growing class of approved and investigational drug therapies that is contributing significantly to…”
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Safety, tolerability, pharmacodynamics and pharmacokinetics of albiglutide, a long-acting glucagon-like peptide-1 mimetic, in healthy subjects by Bush, M.A, Matthews, J.E, De Boever, E.H, Dobbins, R.L, Hodge, R.J, Walker, S.E, Holland, M.C, Gutierrez, M, Stewart, M.W

“…Albiglutide is a glucagon-like peptide-1 (GLP-1) mimetic generated by genetic fusion of a dipeptidyl peptidase-IV-resistant GLP-1 dimer to human albumin…”
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Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis by Glanz, BI, Holland, CM, Gauthier, SA, Amunwa, EL, Liptak, Z., Houtchens, MK, Sperling, RA, Khoury, SJ, Guttmann, CRG, Weiner, HL

“…Cognitive dysfunction is common in patients with multiple sclerosis (MS), and has been associated with MRI measures of lesion burden and atrophy. Little is…”
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Coherent population trapping of electron spins in a high-purity n-type GaAs semiconductor by FU, Kai-Mei C, SANTORI, Charles, STANLEY, Colin, HOLLAND, M. C, YAMAMOTO, Yoshihisa

“…In high-purity n-type GaAs under a strong magnetic field, we are able to isolate a lambda system composed of two Zeeman states of neutral-donor-bound electrons…”
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Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma by YOKOYAMA, Y, CHARNOCK-JONES, D. S, MIZUNUMA, H, SMITH, S. K, LICENCE, D, YANAIHARA, A, HASTINGS, J. M, HOLLAND, C. M, EMOTO, M, UMEMOTO, M, SAKAMOTO, T, SATO, S

“…We assessed the presence of vascular endothelial growth factor (VEGF)-C, VEGF-D and their receptor VEGFR-3 by immunohistochemistry in 59 epithelial ovarian…”
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Ultrafast control of donor-bound electron spins with single detuned optical pulses by Fu, Kai-Mei C, Clark, Susan M, Santori, Charles, Stanley, Colin R, Holland, M. C, Yamamoto, Yoshihisa

“…The ability to control spins in semiconductors is important in a variety of fields, including spintronics and quantum information processing. Due to the…”
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A Planar Gunn Diode Operating Above 100 GHz by Khalid, A., Pilgrim, N.J., Dunn, G.M., Holland, M.C., Stanley, C.R., Thayne, I.G., Cumming, D.R.S.

“…We show the experimental realization of a 108-GHz planar Gunn diode structure fabricated in GaAs/AlGaAs. There is a considerable interest in such devices since…”
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Expression of the VEGF and angiopoietin genes in endometrial atypical hyperplasia and endometrial cancer by Holland, C M, Day, K, Evans, A, Smith, S K

“…Angiogenesis is critical for the growth and metastasis of endometrial cancer and is therefore an important therapeutic target. Vascular endothelial growth…”
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Seasonal fluctuations in pituitary levels of the three forms of gonadotropin-releasing hormone in striped bass, Morone saxatilis (Teleostei), during juvenile and pubertal development by Holland, MC, Hassin, S, Zohar, Y

“…In most vertebrates, the development of a mature gonadotropin-releasing hormone (GnRH) secretory system is pivotal for the onset of puberty. The role of the…”
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Translational research in gynaecological oncology by Holland, C M

“…Please cite this paper as: Holland C. Translational research in gynaecological oncology. BJOG 2008;115:548-550…”
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A nanoanalytical investigation of high- k dielectric gate stacks for GaAs based MOSFET devices by Longo, P., Craven, A.J., Holland, M.C., Moran, D.A.J., Thayne, I.G.

“…In this paper a quantitative determination of the elemental distributions across a ∼10 nm Ga 2O 3/GdGaO layer with a Pt metal gate cap on top of an…”
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Can acyclic conformational control be achieved via a sulfur-fluorine gauche effect? by Thiehoff, C, Holland, M C, Daniliuc, C, Houk, K N, Gilmour, R

“…The conformation of the 1,2-difluoroethane motif is known to involve stabilising hyperconjugative interactions between donor (bonding, ) and acceptor…”
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Unilateral inguinofemoral lymphadenectomy in patients with early-stage vulvar squamous cell carcinoma and a unilateral metastatic sentinel lymph node is safe by Van der Kolk, W.L., Van der Zee, A.G.J., Slomovitz, B.M., Baldwin, P.J.W., Van Doorn, H.C., De Hullu, J.A., Van der Velden, J., Gaarenstroom, K.N., Slangen, B.F.M., Kjolhede, P., Brännström, M., Vergote, I., Holland, C.M., Coleman, R., Van Dorst, E.B.L., Van Driel, W.J., Nunns, D., Widschwendter, M., Nugent, D., DiSilvestro, P.A., Mannel, R.S., Tjiong, M.Y., Boll, D., Cibula, D., Covens, A., Provencher, D., Runnebaum, I.B., Monk, B.J., Zanagnolo, V., Tamussino, K., Oonk, M.H.M., Levenback, C.F., Hermans, R.H., Bouda, J., Sharma, A., Luesley, D., Ellis, P., Cruickshank, D.J., Duncan, T.J., Kieser, K., Palle, C., Spirtos, N.M., O'Malley, D.M., Leitao, M.M., Geller, M., Dhar, K., Asher, V., Tobias, D.H., Borgfeldt, C., Lea, J.S., Lood, M., Bailey, J., Eyjolfsdottir, B., Attard-Montalto, S., Tewari, K.S., Persson, P., Manchanda, R., Jensen, P., Van Le, L.

“…OBJECTIVEOptimal management of the contralateral groin in patients with early-stage vulvar squamous cell carcinoma (VSCC) and a metastatic unilateral inguinal…”
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Fiber digestion kinetics and protein degradability characteristics of stockpiled Tifton 85 bermudagrass by Sechler, S R, Mullenix, M K, Holland, C M, Muntifering, R B

“…A 2-yr study was conducted to determine effects of N fertilization level on fiber digestion kinetics and protein degradability characteristics of stockpiled…”
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Autoantibodies to Variable Heavy (VH) Chain Ig Sequences in Humans Impact the Safety and Clinical Pharmacology of a VH Domain Antibody Antagonist of TNF-α Receptor 1 by Holland, M. C., Wurthner, J. U., Morley, P. J., Birchler, M. A., Lambert, J., Albayaty, M., Serone, A. P., Wilson, R., Chen, Y., Forrest, R. M, Cordy, J. C., Lipson, D. A., Bayliffe, A. I.

“…Purpose To investigate the impact of a new class of anti-Ig autoantibodies reactive with variable heavy (V H ) chain framework sequences (human anti-V H…”
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A simple model for MBE growth controlled by group III atom migration by Holland, M.C.

“…A model that simulates group III atoms of various migration lengths is presented. A number of real MBE growth phenomena have been simulated, including RHEED…”
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Electron transport anisotropies in pseudomorphic InGaAs channel materials and their structural origin by Wilson, J. A., MacKenzie, M., MacFadzean, S., McMullen, T., Hamill, S., Stopford, P., Holland, M. C., Stanley, C. R., Long, A. R.

“…Measurements of the electron transport properties in Inx Ga1−x As (x  = 0.2 and x  = 0.3) channel heterostructures have consistently shown the transport…”
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Can acyclic conformational control be achieved via a sulfur-fluorine gauche effect?Electronic supplementary information (ESI) available. CCDC 1048074-1048078. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc00871a by Thiehoff, C, Holland, M. C, Daniliuc, C, Houk, K. N, Gilmour, R

“…The gauche conformation of the 1,2-difluoroethane motif is known to involve stabilising hyperconjugative interactions between donor (bonding, σ C-H ) and…”
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Anisotropic piezoelectric effect in lateral surface superlattices by Skuras, E., Long, A. R., Larkin, I. A., Davies, J. H., Holland, M. C.

“…We have studied the potential induced by lateral surface superlattices deposited on a GaAs/AlGaAs heterostructure as a function of bias and orientation of the…”
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From atoms to systems: a cross-disciplinary approach to complement-mediated functions by Mastellos, D, Morikis, D, Strey, C, Holland, M.C, Lambris, J.D

“…With an ever-increasing wealth of information made available to researchers from expanding genomic sequence and protein structure databases, traditional…”
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