Search Results - "Holland, Anthony J"

Assessment of objectively measured physical activity levels in individuals with intellectual disabilities with and without Down's syndrome by Phillips, Alexander C, Holland, Anthony J

“…To investigate, using accelerometers, the levels of physical activity being undertaken by individuals with intellectual disabilities with and without Down's…”
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Psychosis in autism: comparison of the features of both conditions in a dually affected cohort by Larson, Felicity V, Wagner, Adam P, Jones, Peter B, Tantam, Digby, Lai, Meng-Chuan, Baron-Cohen, Simon, Holland, Anthony J

“…There is limited information on the presentation and characteristics of psychotic illness experienced by people with autism spectrum disorder (ASD). To…”
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Psychotic illness in people with Prader-Willi syndrome: a systematic review of clinical presentation, course and phenomenology by Aman, Lucie C S, Lester, Suzannah D, Holland, Anthony J, Fletcher, Paul C

“…Prader-Willi syndrome (PWS) is a rare and complex neurodevelopmental disorder resulting from absent paternal expression of maternally imprinted genes at…”
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Transcutaneous vagus nerve stimulation (t-VNS): A novel effective treatment for temper outbursts in adults with Prader-Willi Syndrome indicated by results from a non-blind study by Manning, Katherine E, Beresford-Webb, Jessica A, Aman, Lucie C S, Ring, Howard A, Watson, Peter C, Porges, Stephen W, Oliver, Chris, Jennings, Sally R, Holland, Anthony J

“…Temper outbursts are a severe problem for people with Prader-Willi Syndrome (PWS). Previous reports indicate that vagus nerve stimulation (VNS) may reduce…”
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Grey matter volume and cortical structure in Prader-Willi syndrome compared to typically developing young adults by Manning, Katherine E., Tait, Roger, Suckling, John, Holland, Anthony J.

“…Prader-Willi syndrome (PWS) is a neurodevelopmental disorder of genomic imprinting, presenting with a characteristic overeating disorder, mild to moderate…”
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Time for a general approval of growth hormone treatment in adults with Prader-Willi syndrome by Höybye, Charlotte, Holland, Anthony J, Driscoll, Daniel J

“…Prader-Willi syndrome (PWS) is a complex, multi-system, neurodevelopmental disorder characterised by neonatal muscular hypotonia, short stature, high risk of…”
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Increased brain age in adults with Prader-Willi syndrome by Azor, Adriana M., Cole, James H., Holland, Anthony J., Dumba, Maureen, Patel, Maneesh C., Sadlon, Angelique, Goldstone, Anthony P., Manning, Katherine E.

“…Prader-Willi syndrome (PWS) is the most common genetic obesity syndrome, with associated learning difficulties, neuroendocrine deficits, and behavioural and…”
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Long-term cognitive outcome in adult survivors of an early childhood posterior fossa brain tumour by Wagner, Adam P., Carroll, Cliodhna, White, Simon R., Watson, Peter, Spoudeas, Helen A., Hawkins, Michael M., Walker, David A., Clare, Isabel C. H., Holland, Anthony J., Ring, Howard

“…Purpose Posterior fossa brain tumours (PFT) and their treatment in young children are often associated with subsequent cognitive impairment. However, reported…”
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Dissociable Contributions of the Human Amygdala and Orbitofrontal Cortex to Incentive Motivation and Goal Selection by Arana, F. Sergio, Parkinson, John A, Hinton, Elanor, Holland, Anthony J, Owen, Adrian M, Roberts, Angela C

“…Theories of incentive motivation attempt to capture the way in which objects and events in the world can acquire high motivational value and drive behavior,…”
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Testing the 'Extreme Female Brain' Theory of Psychosis in Adults with Autism Spectrum Disorder with or without Co-Morbid Psychosis by Larson, Felicity V, Lai, Meng-Chuan, Wagner, Adam P, Baron-Cohen, Simon, Holland, Anthony J

“…Males and females in the general population differ, on average, in their drive for empathizing (higher in females) and systemizing (higher in males). People…”
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Atypical Movement Performance and Sensory Integration in Asperger’s Syndrome by Siaperas, Panagiotis, Ring, Howard A., McAllister, Catherine J., Henderson, Sheila, Barnett, Anna, Watson, Peter, Holland, Anthony J.

“…The aims of this study were to investigate whether individuals with AS have impaired motor abilities and sensorimotor processing and whether these impairments…”
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The validity and reliability of the CAMDEX-DS for assessing dementia in adults with Down syndrome in Brazil by Fonseca, Luciana M, Haddad, Glenda G, Mattar, Guilherme P, Oliveira, Melaine C de, Simon, Sharon S, Guilhoto, Laura M, Busatto, Geraldo F, Zaman, Shahid, Holland, Anthony J, Hoexter, Marcelo Q, Bottino, Cassio M

“…Alzheimer's disease occurs at a higher prevalence and an earlier age in individuals with Down syndrome (DS) than typically developing individuals. However,…”
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Establishing diagnostic thresholds for Alzheimer's disease in adults with Down syndrome: the Cambridge Examination for Mental Disorders of Older People with Down's Syndrome and Others with Intellectual Disabilities (CAMDEX-DS) by Beresford-Webb, Jessica A., Mak, Elijah, Grigorova, Monika, Daffern, Samuel J., Holland, Anthony J., Zaman, Shahid H.

“…Diagnosis of prodromal Alzheimer's disease and Alzheimer's disease dementia in people with Down syndrome is a major challenge. The Cambridge Examination for…”
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Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report by Mak, Elijah, Bickerton, Anastasia, Padilla, Concepcion, Walpert, Madeleine J., Annus, Tiina, Wilson, Liam R., Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Christian, Bradley T., Handen, Benjamin L., Klunk, William E., Menon, David K., Nestor, Peter J., Zaman, Shahid H., Holland, Anthony J.

“…Comorbid Alzheimer disease pathologies are frequently found in people with Down syndrome (DS). We report a deep phenotyping study undertaken over 7 years in a…”
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Neural contributions to the motivational control of appetite in humans by Hinton, Elanor C., Parkinson, John A., Holland, Anthony J., Arana, F. Sergio, C. Roberts, Angela, Owen, Adrian M.

“…The motivation to eat in humans is a complex process influenced by intrinsic mechanisms relating to the hunger and satiety cascade, and extrinsic mechanisms…”
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Changing rates of genetic subtypes of Prader-Willi syndrome in the UK by WHITTINGTON, Joyce E, BUTLER, Jill V, HOLLAND, Anthony J

“…The genetically determined neurodevelopmental disorder, Prader-Willi syndrome (PWS), has two main genetic subtypes: a 15q11-q13 deletion affecting the…”
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Age-related retinal thickness in Down's syndrome: A high-risk population for dementia by Walpert, Madeleine J., Normando, Eduardo M., Annus, Tiina, Jennings, Sally R., Wilson, Liam R., Watson, Peter, Zaman, Shahid H., Cordeiro, M. Francesca, Holland, Anthony J.

“…People with Down's syndrome (DS) have a high prevalence of early-onset Alzheimer's disease. Early markers of Alzheimer's disease pathology identifiable before…”
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Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study by Fortea, Juan, Vilaplana, Eduard, Carmona-Iragui, Maria, Benejam, Bessy, Videla, Laura, Barroeta, Isabel, Fernández, Susana, Altuna, Miren, Pegueroles, Jordi, Montal, Víctor, Valldeneu, Silvia, Giménez, Sandra, González-Ortiz, Sofía, Muñoz, Laia, Estellés, Teresa, Illán-Gala, Ignacio, Belbin, Olivia, Camacho, Valle, Wilson, Liam Reese, Annus, Tiina, Osorio, Ricardo S, Videla, Sebastián, Lehmann, Sylvain, Holland, Anthony J, Alcolea, Daniel, Clarimón, Jordi, Zaman, Shahid H, Blesa, Rafael, Lleó, Alberto

“…Alzheimer's disease and its complications are the leading cause of death in adults with Down syndrome. Studies have assessed Alzheimer's disease in individuals…”
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Defective mitochondrial function in vivo in skeletal muscle in adults with Down's syndrome: a 31P-MRS study by Phillips, Alexander C, Sleigh, Alison, McAllister, Catherine J, Brage, Soren, Carpenter, T Adrian, Kemp, Graham J, Holland, Anthony J

“…Down's syndrome (DS) is a developmental disorder associated with intellectual disability (ID). We have previously shown that people with DS engage in very low…”
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Brain-predicted age in Down Syndrome is associated with β-amyloid deposition and cognitive decline by Cole, James H, Annus, Tiina, Wilson, Liam R, Remtulla, Ridhaa, Hong, Young T, Fryer, Tim D, Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Smith, Robert, Menon, David K, Zaman, Shahid H, Nestor, Peter J, Holland, Anthony J

“…Abstract Individuals with Down Syndrome (DS) are more likely to experience earlier onset of multiple facets of physiological ageing. This includes brain…”
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