Search Results - "Holla, Andrea"

Comparative analysis reveals selective recognition of glycans by the dendritic cell receptors DC-SIGN and Langerin by Holla, Andrea, Skerra, Arne

“…DC-SIGN (dendritic cell-specific ICAM-3 grabbing non-integrin) and Langerin are homologous C-type lectins expressed as cell-surface receptors on different…”
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Integrated view of internal friction in unfolded proteins from single-molecule FRET, contact quenching, theory, and simulations by Soranno, Andrea, Holla, Andrea, Dingfelder, Fabian, Nettels, Daniel, Makarov, Dmitrii E., Schuler, Benjamin

“…Internal friction is an important contribution to protein dynamics at all stages along the folding reaction. Even in unfolded and intrinsically disordered…”
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Single-Molecule Spectroscopy of Cold Denaturation and the Temperature-Induced Collapse of Unfolded Proteins by Aznauryan, Mikayel, Nettels, Daniel, Holla, Andrea, Hofmann, Hagen, Schuler, Benjamin

“…Recent Förster resonance energy transfer (FRET) experiments show that heat-unfolded states of proteins become more compact with increasing temperature. At the…”
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Global Structure of the Intrinsically Disordered Protein Tau Emerges from Its Local Structure by Stelzl, Lukas S, Pietrek, Lisa M, Holla, Andrea, Oroz, Javier, Sikora, Mateusz, Köfinger, Jürgen, Schuler, Benjamin, Zweckstetter, Markus, Hummer, Gerhard

“…The paradigmatic disordered protein tau plays an important role in neuronal function and neurodegenerative diseases. To disentangle the factors controlling the…”
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Labeling of Proteins for Single-Molecule Fluorescence Spectroscopy by Zosel, Franziska, Holla, Andrea, Schuler, Benjamin

“…Single-molecule fluorescence spectroscopy has become an important technique for studying the conformational dynamics and folding of proteins. A key step for…”
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Combining Rapid Microfluidic Mixing and Three-Color Single-Molecule FRET for Probing the Kinetics of Protein Conformational Changes by Benke, Stephan, Holla, Andrea, Wunderlich, Bengt, Soranno, Andrea, Nettels, Daniel, Schuler, Benjamin

“…Single-molecule Förster resonance energy transfer (FRET) is well suited for studying the kinetics of protein conformational changes, owing to its high…”
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Local and Global Dynamics in Intrinsically Disordered Synuclein by Rezaei‐Ghaleh, Nasrollah, Parigi, Giacomo, Soranno, Andrea, Holla, Andrea, Becker, Stefan, Schuler, Benjamin, Luchinat, Claudio, Zweckstetter, Markus

“…Intrinsically disordered proteins (IDPs) experience a diverse spectrum of motions that are difficult to characterize with a single experimental technique…”
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Resolving distance variations by single-molecule FRET and EPR spectroscopy using rotamer libraries by Klose, Daniel, Holla, Andrea, Gmeiner, Christoph, Nettels, Daniel, Ritsch, Irina, Bross, Nadja, Yulikov, Maxim, Allain, Frédéric H.-T., Schuler, Benjamin, Jeschke, Gunnar

“…Förster resonance energy transfer (FRET) and electron paramagnetic resonance (EPR) spectroscopy are complementary techniques for quantifying distances in the…”
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From integrative atomic-resolution ensembles of disordered proteins to simulations of phase-separated condensates by Stelzl, Lukas S., Pietrek, Lisa M., Ping, Xiaofei, Holla, Andrea, Sikora, Mateusz, Koefinger, Juergen, Dormann, Dorothee, Schuler, Benjamin, Zweckstetter, Markus, Hummer, Gerhard

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Resolving the Dynamics of the Double Stranded RNA Binding Protein TRBP by Stach, Oliver, König, Sebastian L., Holla, Andrea, Sturzenegger, Flurin, Doden, Sebastian, Nettels, Daniel, Schuler, Benjamin

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Structural basis of siRNA recognition by TRBP double‐stranded RNA binding domains by Masliah, Gregoire, Maris, Christophe, König, Sebastian LB, Yulikov, Maxim, Aeschimann, Florian, Malinowska, Anna L, Mabille, Julie, Weiler, Jan, Holla, Andrea, Hunziker, Juerg, Meisner‐Kober, Nicole, Schuler, Benjamin, Jeschke, Gunnar, Allain, Frederic H‐T

“…The accurate cleavage of pre‐micro(mi)RNAs by Dicer and mi/siRNA guide strand selection are important steps in forming the RNA‐induced silencing complex…”
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Integrated View of Internal Friction in Unfolded Proteins from Single-Molecule FRET, Contact Quenching, Theory, and Simulations by Soranno, Andrea, Holla, Andrea, Dingfelder, Fabian, Nettels, Daniel, Makarov, Dmitrii E., Schuler, Benjamin

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Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations by Holla, Andrea, Martin, Erik W., Dannenhoffer-Lafage, Thomas, Ruff, Kiersten M., König, Sebastian L. B., Nüesch, Mark F., Chowdhury, Aritra, Louis, John M., Soranno, Andrea, Nettels, Daniel, Pappu, Rohit V., Best, Robert B., Mittag, Tanja, Schuler, Benjamin

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Structural basis of si RNA recognition by TRBP double‐stranded RNA binding domains by Masliah, Gregoire, Maris, Christophe, König, Sebastian LB, Yulikov, Maxim, Aeschimann, Florian, Malinowska, Anna L, Mabille, Julie, Weiler, Jan, Holla, Andrea, Hunziker, Juerg, Meisner‐Kober, Nicole, Schuler, Benjamin, Jeschke, Gunnar, Allain, Frederic H‐T

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The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site by Chatwell, Lorenz, Holla, Andrea, Kaufer, Benedikt B., Skerra, Arne

“…Langerin is a type II transmembrane oligosaccharide receptor on Langerhans cells (LCs), a prominent subclass of dendritic cells (DCs) that mediate immune…”
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Accurate Transfer Efficiencies, Distance Distributions, and Ensembles of Unfolded and Intrinsically Disordered Proteins From Single-Molecule FRET by Holmstrom, Erik D, Holla, Andrea, Zheng, Wenwei, Nettels, Daniel, Best, Robert B, Schuler, Benjamin

“…Intrinsically disordered proteins (IDPs) sample structurally diverse ensembles. Characterizing the underlying distributions of conformations is a key step…”
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Lokale und globale Dynamik im ungeordneten Synuklein‐Protein by Rezaei‐Ghaleh, Nasrollah, Parigi, Giacomo, Soranno, Andrea, Holla, Andrea, Becker, Stefan, Schuler, Benjamin, Luchinat, Claudio, Zweckstetter, Markus

“…Intrinsisch ungeordnete Proteine (IDPs) besitzen ein breites Spektrum an Bewegungen, die mit einer einzelnen experimentellen Methode schwierig zu…”
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