Search Results - "Holicek, Peter"

Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients by Truxova, Iva, Kasikova, Lenka, Salek, Cyril, Hensler, Michal, Lysak, Daniel, Holicek, Peter, Bilkova, Pavla, Holubova, Monika, Chen, Xiufen, Mikyskova, Romana, Reinis, Milan, Kovar, Marek, Tomalova, Barbora, Kline, Justin P, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka

“…In some settings, cancer cells responding to treatment undergo an immunogenic form of cell death that is associated with the abundant emission of danger…”
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Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients by Holicek, Peter, Truxova, Iva, Rakova, Jana, Salek, Cyril, Hensler, Michal, Kovar, Marek, Reinis, Milan, Mikyskova, Romana, Pasulka, Josef, Vosahlikova, Sarka, Remesova, Hana, Valentova, Iva, Lysak, Daniel, Holubova, Monika, Kaspar, Petr, Prochazka, Jan, Kasikova, Lenka, Spisek, Radek, Galluzzi, Lorenzo, Fucikova, Jitka

“…While type I interferon (IFN) is best known for its key role against viral infection, accumulating preclinical and clinical data indicate that robust type I…”
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TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients by Rakova, Jana, Truxova, Iva, Holicek, Peter, Salek, Cyril, Hensler, Michal, Kasikova, Lenka, Pasulka, Josef, Holubova, Monika, Kovar, Marek, Lysak, Daniel, Kline, Justin P., Racil, Zdenek, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka

“…Accumulating evidence indicates that immune checkpoint inhibitors (ICIs) can restore CD8 + cytotoxic T lymphocyte (CTL) functions in preclinical models of…”
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Peripheral gene signatures reveal distinct cancer patient immunotypes with therapeutic implications for autologous DC-based vaccines by Hensler, Michal, Rakova, Jana, Kasikova, Lenka, Lanickova, Tereza, Pasulka, Josef, Holicek, Peter, Hraska, Marek, Hrnciarova, Tereza, Kadlecova, Pavla, Schoenenberger, Andreu, Sochorova, Klara, Rozkova, Daniela, Sojka, Ludek, Drozenova, Jana, Laco, Jan, Horvath, Rudolf, Podrazil, Michal, Hongyan, Guo, Brtnicky, Tomas, Halaska, Michal J., Rob, Lukas, Ryska, Ales, Coosemans, An, Vergote, Ignace, Garg, Abhishek D., Cibula, David, Bartunkova, Jirina, Spisek, Radek, Fucikova, Jitka

“…Dendritic cells (DCs) have received considerable attention as potential targets for the development of novel cancer immunotherapies. However, the clinical…”
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Type I interferon and cancer by Holicek, Peter, Guilbaud, Emma, Klapp, Vanessa, Truxova, Iva, Spisek, Radek, Galluzzi, Lorenzo, Fucikova, Jitka

“…Summary Type I interferon (IFN) is a class of proinflammatory cytokines with a dual role on malignant transformation, tumor progression, and response to…”
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Interferon signaling restrains renal cell carcinoma heterogeneity by Holicek, Peter, Fucikova, Jitka, Galluzzi, Lorenzo

“…Type I interferon (IFN) is central to cancer surveillance as it mediates both direct and immune-mediated oncosuppressive effects. A recent study by Perelli et…”
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Immune response to cold exposure: Role of γδ T cells and TLR2‐mediated inflammation by Vasek, Daniel, Holicek, Peter, Galatik, Frantisek, Kratochvilova, Anna, Porubska, Bianka, Somova, Veronika, Fikarova, Natalie, Hajkova, Michaela, Prevorovsky, Martin, Zurmanova, Jitka M, Krulova, Magdalena

“…The mammalian body possesses remarkable adaptability to cold exposure, involving intricate adjustments in cellular metabolism, ultimately leading to…”
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Immunological control of ovarian carcinoma by chemotherapy and targeted anticancer agents by Fucikova, Jitka, Palova-Jelinkova, Lenka, Klapp, Vanessa, Holicek, Peter, Lanickova, Tereza, Kasikova, Lenka, Drozenova, Jana, Cibula, David, Álvarez-Abril, Beatriz, García-Martínez, Elena, Spisek, Radek, Galluzzi, Lorenzo

“…At odds with other solid tumors, epithelial ovarian cancer (EOC) is poorly sensitive to immune checkpoint inhibitors (ICIs), largely reflecting active…”
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Abstract C046: PARP inhibitors as immune modulators in metastatic ovarian cancer treatment by Vosahlikova, Sarka, Holicek, Peter, Moserova, Irena, Hensler, Michal, Mikyskova, Romana, Kasikova, Lenka, Pasuvka, Josef, Drozenova, Jana, Mojzisova, Katerina, Kovar, Marek, McNiesh, Iain, Halaska, Michael, Rob, Lukas, Orsulic, Sandra, Reinis, Milan, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka Palich

“…Abstract Epithelial ovarian carcinoma (EOC) is one of the top five causes of cancer-related death in women. Most patients with EOC achieve initial remission…”
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Abstract 5278: Immunological control by PARP inhibitors for successful immunotherapy in metastatic ovarian carcinoma by Holicek, Peter, Vosahlikova, Sarka, Moserova, Irena, Orsulic, Sandra, Mikyskova, Romana, Hensler, Michal, Kasikova, Lenka, Lanickova, Tereza, Novotny, Ondrej, Reinis, Milan, Drozenova, Jana, Ryska, Ales, Laco, Jan, Rob, Lukas, Halaska, Michael, Cibula, David, Spisek, Radek, Fucikova, Jitka

“…Abstract Epithelial ovarian carcinoma (EOC) is among the top five causes of cancer-related death in women. Most women with EOC achieve indeed complete…”
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Assessment of NK cell-mediated cytotoxicity by flow cytometry after rapid, high-yield isolation from peripheral blood by Holicek, Peter, Truxova, Iva, Kasikova, Lenka, Vosahlikova, Sarka, Salek, Cyril, Rakova, Jana, Holubova, Monika, Lysak, Daniel, Cremer, Isabelle, Spisek, Radek, Fucikova, Jitka

“…Natural killer (NK) cells constitute the predominant innate lymphocyte subset that mediates the anti-viral and anti-tumor immune responses. NK cells use an…”
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