Search Results - "Holguín, Almudena"
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In vitro and In vivo Wound Healing-Promoting Activities of Human Cathelicidin LL-37
Published in Journal of investigative dermatology (01-01-2008)“…The human antimicrobial peptide LL-37 plays an important role in host defense against infection. In addition to its antimicrobial action, other activities have…”
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A humanized mouse model of HPV-associated pathology driven by E7 expression
Published in PloS one (23-07-2012)“…Human papillomavirus (HPV) is the causative agent of human cervical cancer and has been associated with oropharyngeal squamous cell carcinoma development…”
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The regenerative potential of fibroblasts in a new diabetes-induced delayed humanised wound healing model
Published in Experimental dermatology (01-03-2013)“…Cutaneous diabetic wounds greatly affect the quality of life of patients, causing a substantial economic impact on the healthcare system. The limited clinical…”
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Assessment of Optimal Virus-Mediated Growth Factor Gene Delivery for Human Cutaneous Wound Healing Enhancement
Published in Journal of investigative dermatology (01-06-2008)“…Using a recently described skin-humanized model based on the engraftment of human bioengineered skin equivalents onto immunodeficient mice, we compared the…”
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Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells
Published in Molecular therapy. Nucleic acids (01-06-2018)“…Recessive dystrophic epidermolysis bullosa is a severe skin fragility disease caused by loss of functional type VII collagen at the dermal-epidermal junction…”
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Development of a Bioengineered Skin-Humanized Mouse Model for Psoriasis: Dissecting Epidermal-Lymphocyte Interacting Pathways
Published in The American journal of pathology (01-12-2010)“…Over the past few years, whole skin xenotransplantation models that mimic different aspects of psoriasis have become available. However, these models are…”
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Establishment of a murine epidermal cell line suitable for in vitro and in vivo skin modelling
Published in BMC dermatology (21-04-2011)“…Skin diseases are a major health problem. Some of the most severe conditions involve genetic disorders, including cancer. Several of these human diseases have…”
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Development of a Bioengineered Skin-Humanized Mouse Model for Psoriasis
Published in The American journal of pathology (01-12-2010)“…Over the past few years, whole skin xenotransplantation models that mimic different aspects of psoriasis have become available. However, these models are…”
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In vitro and In vivo Wound Healing-Promoting Activities of Human Cathelicidin LL-37. Commentary
Published in Journal of investigative dermatology (2008)Get full text
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210. Permanent Correction of Leptin Deficiency through Cutaneous Gene Therapy. Lentivirus but Not Retrovirus-Transduced Human Keratinocyte Orthotopic Grafts Achieve Therapeutic Systemic Leptin Levels
Published in Molecular therapy (01-05-2006)“…Leptin deficiencies are involved in rare cases of inherited human obesity and in various forms of lipodystrophy. Previous results from our laboratory showed…”
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