Search Results - "Holgersen, Erle M"

The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression by Espiritu, Shadrielle Melijah G., Liu, Lydia Y., Rubanova, Yulia, Bhandari, Vinayak, Holgersen, Erle M., Szyca, Lesia M., Fox, Natalie S., Chua, Melvin L.K., Yamaguchi, Takafumi N., Heisler, Lawrence E., Livingstone, Julie, Wintersinger, Jeff, Yousif, Fouad, Lalonde, Emilie, Rouette, Alexandre, Salcedo, Adriana, Houlahan, Kathleen E., Li, Constance H., Huang, Vincent, Fraser, Michael, van der Kwast, Theodorus, Morris, Quaid D., Bristow, Robert G., Boutros, Paul C.

“…The majority of newly diagnosed prostate cancers are slow growing, with a long natural life history. Yet a subset can metastasize with lethal consequences. We…”
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Transcriptome-Wide Off-Target Effects of Steric-Blocking Oligonucleotides by Holgersen, Erle M, Gandhi, Shreshth, Zhou, Yongchao, Kim, Jinkuk, Vaz, Brandon, Bogojeski, Jovanka, Bugno, Magdalena, Shalev, Zvi, Cheung-Ong, Kahlin, Gonçalves, João, O'Hara, Matthew, Kron, Ken, Verby, Marta, Sun, Mark, Kakaradov, Boyko, Delong, Andrew, Merico, Daniele, Deshwar, Amit G

“…Steric-blocking oligonucleotides (SBOs) are short, single-stranded nucleic acids designed to modulate gene expression by binding to RNA transcripts and…”
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Identifying high-confidence capture Hi-C interactions using CHiCANE by Holgersen, Erle M., Gillespie, Andrea, Leavy, Olivia C., Baxter, Joseph S., Zvereva, Alisa, Muirhead, Gareth, Johnson, Nichola, Sipos, Orsolya, Dryden, Nicola H., Broome, Laura R., Chen, Yi, Kozin, Igor, Dudbridge, Frank, Fletcher, Olivia, Haider, Syed

“…The ability to identify regulatory interactions that mediate gene expression changes through distal elements, such as risk loci, is transforming our…”
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3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer by Peck, Barrie, Bland, Philip, Mavrommati, Ioanna, Muirhead, Gareth, Cottom, Hannah, Wai, Patty T, Maguire, Sarah L, Barker, Holly E, Morrison, Eamonn, Kriplani, Divya, Yu, Lu, Gibson, Amy, Falgari, Giulia, Brennan, Keith, Farnie, Gillian, Buus, Richard, Marlow, Rebecca, Novo, Daniela, Knight, Eleanor, Guppy, Naomi, Kolarevic, Daniela, Susnjar, Snezana, Milijic, Natasa Medic, Naidoo, Kalnisha, Gazinska, Patrycja, Roxanis, Ioannis, Pancholi, Sunil, Martin, Lesley-Ann, Holgersen, Erle M, Cheang, Maggie C U, Noor, Farzana, Postel-Vinay, Sophie, Quinn, Gerard, McDade, Simon, Krasny, Lukas, Huang, Paul, Daley, Frances, Wallberg, Fredrik, Choudhary, Jyoti S, Haider, Syed, Tutt, Andrew N, Natrajan, Rachael

“…Triple-negative breast cancers (TNBC) are resistant to standard-of-care chemotherapy and lack known targetable driver gene alterations. Identification of novel…”
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