Search Results - "Holgate, Joan Y."

Early Life Stress, Nicotinic Acetylcholine Receptors and Alcohol Use Disorders by Holgate, Joan Y, Bartlett, Selena E

“…Stress is a major driving force in alcohol use disorders (AUDs). It influences how much one consumes, craving intensity and whether an abstinent individual…”
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Social and environmental enrichment has different effects on ethanol and sucrose consumption in mice by Holgate, Joan Y., Garcia, Hilary, Chatterjee, Susmita, Bartlett, Selena E.

“…Background Factors leading to the harmful consumption of substances, like alcohol and sucrose, involve a complex interaction of genes and the environment…”
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Modulation of serotonin and noradrenaline in the BLA by pindolol reduces long‐term ethanol intake by Patkar, Omkar L., Belmer, Arnauld, Holgate, Joan Y., Klenowski, Paul M., Bartlett, Selena E.

“…Repeated cycles of binge‐like alcohol consumption and abstinence change the activity of several neurotransmitter systems. Some of these changes are…”
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A Rat Drinking in the Dark Model for Studying Ethanol and Sucrose Consumption by Holgate, Joan Y, Shariff, Masroor, Mu, Erica W H, Bartlett, Selena

“…: The intermittent access 2-bottle choice (IA2BC) and drinking in the dark (DID) models were developed for studying rodent binge-like consumption…”
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The effect of varenicline on binge-like ethanol consumption in mice is β4 nicotinic acetylcholine receptor-independent by Patkar, Omkar L., Belmer, Arnauld, Tarren, Josephine R., Holgate, Joan Y., Bartlett, Selena E.

“…•Genetic ablation of β4 nicotinic acetylcholine receptor subunit does not affect ethanol drinking in mice in the drinking in the dark paradigm.•The…”
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The antihypertensive drug pindolol attenuates long‐term but not short‐term binge‐like ethanol consumption in mice by Patkar, Omkar L., Belmer, Arnauld, Holgate, Joan Y., Tarren, Josephine R., Shariff, Masroor R., Morgan, Michael, Fogarty, Matthew J., Bellingham, Mark C., Bartlett, Selena E., Klenowski, Paul M.

“…Alcohol dependence is a debilitating disorder with current therapies displaying limited efficacy and/or compliance. Consequently, there is a critical need for…”
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Induction of multiple reinstatements of ethanol- and sucrose-seeking behavior in Long-Evans rats by the [alpha]-2 adrenoreceptor antagonist yohimbine by Simms, Jeffrey A, Richards, Jemma K, Mill, Douglas, Kanholm, Isabel, Holgate, Joan Y, Bartlett, Selena E

“…Developing models to efficiently explore the mechanisms by which stress can mediate reinstatement of drug-seeking behavior is crucial to the development of new…”
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Induction of multiple reinstatements of ethanol- and sucrose-seeking behavior in Long–Evans rats by the α-2 adrenoreceptor antagonist yohimbine by Simms, Jeffrey A., Richards, Jemma K., Mill, Douglas, Kanholm, Isabel, Holgate, Joan Y., Bartlett, Selena E.

“…Rationale Developing models to efficiently explore the mechanisms by which stress can mediate reinstatement of drug-seeking behavior is crucial to the…”
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Sex Specific Alterations in α4Nicotinic Receptor Expression in the Nucleus Accumbens by Holgate, Joan Y, Tarren, Josephine R, Bartlett, Selena E

“…: The mechanisms leading from traumatic stress to social, emotional and cognitive impairment and the development of mental illnesses are still undetermined and…”
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Induction of multiple reinstatements of ethanol- and sucrose-seeking behavior in Long―Evans rats by the α-2 adrenoreceptor antagonist yohimbine: Special Issue on Stress, Alcohol and Drug Abuse by SIMMS, Jeffrey A, RICHARDS, Jemma K, MILL, Douglas, KANHOLM, Isabel, HOLGATE, Joan Y, BARTLETT, Selena E

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