Search Results - "Holgado, M A"

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    Nanostructures for drug delivery to the brain by Martin-Banderas, L, Holgado, M A, Venero, J L, Alvarez-Fuentes, J, Fernández-Arévalo, M

    Published in Current medicinal chemistry (01-12-2011)
    “…This review aims to summarize present approaches employed in delivering drugs to the central nervous system. Changes in blood-brain barrier (BBB) function have…”
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    Drug targeting to cancer by nanoparticles surface functionalized with special biomolecules by Holgado, M A, Martin-Banderas, L, Alvarez-Fuentes, J, Fernandez-Arevalo, M, Arias, J L

    Published in Current medicinal chemistry (01-07-2012)
    “…Nanoparticulate-based drug carriers have been developed to overcome the problems of conventional anticancer pharmacotherapy, i.e., the little specificity and…”
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    Functional PLGA NPs for oral drug delivery: recent strategies and developments by Martin-Banderas, L, Durán-Lobato, M, Muñoz-Rubio, I, Alvarez-Fuentes, J, Fernández-Arevalo, M, Holgado, M A

    Published in Mini reviews in medicinal chemistry (01-01-2013)
    “…This article presents the potential of PLGA nanoparticles for the oral administration of drugs. Different strategies are used to improve oral absorption of…”
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    Alginate/chitosan particulate systems for sodium diclofenac release by González-Rodrı́guez, M.L, Holgado, M.A, Sánchez-Lafuente, C, Rabasco, A.M, Fini, A

    Published in International journal of pharmaceutics (31-01-2002)
    “…Alginate/chitosan particles were prepared by ionic gelation (Ca 2+ and Al 3+) for the sodium diclofenac release. The systems were characterized by electron…”
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    Synthesis of lidocaine-loaded PLGA microparticles by flow focusing Effects on drug loading and release properties by HOLGADO, M. A, ARIAS, J. L, COZAR, M. J, ALVAREZ-FUENTES, J, GANAN-CALVO, A. M, FERNANDEZ-AREVALO, M

    Published in International journal of pharmaceutics (24-06-2008)
    “…In the present work, two methods for the preparation of lidocaine-loaded PLGA microparticles are compared. The differences between the polymeric particles…”
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    Possibilities of poly(D,L-lactide-co-glycolide) in the formulation of nanomedicines against cancer by Holgado, M A, Alvarez-Fuentes, J, Fernández-Arévalo, M, Arias, J L

    Published in Current drug targets (01-07-2011)
    “…Due to a very poor specificity, many chemotherapy agents generate a low antitumor effect and important severe side effects. Poly(D,L-lactide-co-glycolide)…”
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    Protein-loaded PLGA microparticles engineered by flow focusing: Physicochemical characterization and protein detection by reversed-phase HPLC by Holgado, M.A., Cózar-Bernal, M.J., Salas, S., Arias, J.L., Álvarez-Fuentes, J., Fernández-Arévalo, M.

    Published in International journal of pharmaceutics (01-10-2009)
    “…In the present study, a novel synthesis technique based on the flow focusing (FF) technology is investigated for the preparation of green fluorescent protein…”
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    Development and in vitro evaluation of a controlled release formulation to produce wide dose interval morphine tablets by Holgado, M.A., Iruin, A., Alvarez-Fuentes, J., Fernández-Arévalo, M.

    “…In this paper, a new pharmaceutical formulation for the administration of morphine has been developed. This system is based on a polymeric complex previously…”
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    Development and Validation of an RP-HPLC Method for CB13 Evaluation in Several PLGA Nanoparticle Systems by Martín-Banderas, Lucía, Álvarez-Fuentes, J., Muñoz-Rubio, I., Holgado, M. A., Fernández-Arévalo, Mercedes

    Published in TheScientificWorld (01-01-2012)
    “…A simple, fast, and reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed and validated for determining of a cannabinoid…”
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    Diclofenac salts. I. Fractal and thermal analysis of sodium and potassium diclofenac salts by Fini, A, Garuti, M, Fazio, G, Alvarez-Fuentes, J, Holgado, M A

    Published in Journal of pharmaceutical sciences (01-12-2001)
    “…Sodium and potassium diclofenac salts form hydrates when crystallized from water; the sodium salt contains four crystallization water molecules, while the…”
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    Elaboration and "In Vitro" Characterization of 5-ASA Beads by Iruín, A., Fernández-Arévalo, M., Álvarez-Fuéntes, J., Fini, A., Holgado, M. A.

    “…The purpose of this research was to perform the design and in vitro evaluation of alginate beads containing 5-ASA in order to achieve an oral system that…”
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    Role of Nanotechnology for Enzyme Replacement Therapy in Lysosomal Diseases. A Focus on Gaucher's Disease by Martín-Banderas, L, Holgado, M A, Durán-Lobato, M, Infante, J J, Álvarez-Fuentes, J, Fernández-Arévalo, M

    Published in Current medicinal chemistry (01-01-2016)
    “…Lysosomal storage diseases (LSDs) comprise a group of rare inherited chronic syndromes that cause deficiency of specific native enzymes within the lysosomes…”
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    In vitro evaluation of alginate beads of a diclofenac salt by Fernández-Hervás, M.J, Holgado, M.A, Fini, A, Fell, J.T

    Published in International journal of pharmaceutics (18-03-1998)
    “…Alginate beads containing diclofenac hydroxyethylpyrrolidine were formulated with either Eudragit or chitosan in order to achieve an enteric formulation. In…”
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    Fractal analysis of beta-cyclodextrin-indomethacin particles compacted by ultrasound by Fini, A, Fernàndez-Hervàs, M J, Holgado, M A, Rodriguez, L, Cavallari, C, Passerini, N, Caputo, O

    Published in Journal of pharmaceutical sciences (01-11-1997)
    “…An association between indomethacin and beta-cyclodextrin (beta-CD) was obtained by compacting a 1:2 molar physical mixture by ultrasound. The product prepared…”
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    Insulin-loaded PLGA microparticles: flow focusing versus double emulsion/solvent evaporation by Cózar-Bernal, M. J., Holgado, M. A., Arias, J. L., Muñoz-Rubio, I., Martín-Banderas, L., Álvarez-Fuentes, J., Fernández-Arévalo, M.

    Published in Journal of microencapsulation (01-08-2011)
    “…Context: Oral administration of insulin is severely limited by very low bioavailability. Biocompatible polymeric nanocarriers have been investigated to…”
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    Effect of the temperature on a hydrate diclofenac salt by Fini, A, Fazio, G, Rabasco, A.M, Fernández-Hervás, M.J, Holgado, M.A

    Published in International journal of pharmaceutics (20-04-1999)
    “…The salt Diclofenac/ N-(2-hydroxyethyl) pyrrolidine when crystallizes from water forms a di-hydrate, which looses the crystallization water molecules on…”
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