Search Results - "Holgado, M A"
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The NANOGrav 11 yr Data Set: Limits on Gravitational Waves from Individual Supermassive Black Hole Binaries
Published in The Astrophysical journal (01-08-2019)“…Observations indicate that nearly all galaxies contain supermassive black holes at their centers. When galaxies merge, their component black holes form SMBH…”
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Nanostructures for drug delivery to the brain
Published in Current medicinal chemistry (01-12-2011)“…This review aims to summarize present approaches employed in delivering drugs to the central nervous system. Changes in blood-brain barrier (BBB) function have…”
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3
Drug targeting to cancer by nanoparticles surface functionalized with special biomolecules
Published in Current medicinal chemistry (01-07-2012)“…Nanoparticulate-based drug carriers have been developed to overcome the problems of conventional anticancer pharmacotherapy, i.e., the little specificity and…”
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4
Functional PLGA NPs for oral drug delivery: recent strategies and developments
Published in Mini reviews in medicinal chemistry (01-01-2013)“…This article presents the potential of PLGA nanoparticles for the oral administration of drugs. Different strategies are used to improve oral absorption of…”
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Alginate/chitosan particulate systems for sodium diclofenac release
Published in International journal of pharmaceutics (31-01-2002)“…Alginate/chitosan particles were prepared by ionic gelation (Ca 2+ and Al 3+) for the sodium diclofenac release. The systems were characterized by electron…”
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Synthesis of lidocaine-loaded PLGA microparticles by flow focusing Effects on drug loading and release properties
Published in International journal of pharmaceutics (24-06-2008)“…In the present work, two methods for the preparation of lidocaine-loaded PLGA microparticles are compared. The differences between the polymeric particles…”
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Possibilities of poly(D,L-lactide-co-glycolide) in the formulation of nanomedicines against cancer
Published in Current drug targets (01-07-2011)“…Due to a very poor specificity, many chemotherapy agents generate a low antitumor effect and important severe side effects. Poly(D,L-lactide-co-glycolide)…”
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Protein-loaded PLGA microparticles engineered by flow focusing: Physicochemical characterization and protein detection by reversed-phase HPLC
Published in International journal of pharmaceutics (01-10-2009)“…In the present study, a novel synthesis technique based on the flow focusing (FF) technology is investigated for the preparation of green fluorescent protein…”
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Development and in vitro evaluation of a controlled release formulation to produce wide dose interval morphine tablets
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2008)“…In this paper, a new pharmaceutical formulation for the administration of morphine has been developed. This system is based on a polymeric complex previously…”
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Modeling the Uncertainties of Solar System Ephemerides for Robust Gravitational-wave Searches with Pulsar-timing Arrays
Published in The Astrophysical journal (01-04-2020)“…The regularity of pulsar emissions becomes apparent once we reference the pulses' times of arrivals to the inertial rest frame of the solar system. It follows…”
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The NANOGrav 11 yr Data Set: Limits on Gravitational Wave Memory
Published in The Astrophysical journal (20-01-2020)“…The mergers of supermassive black hole binaries (SMBHBs) promise to be incredible sources of gravitational waves (GWs). While the oscillatory part of the…”
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12
Development and Validation of an RP-HPLC Method for CB13 Evaluation in Several PLGA Nanoparticle Systems
Published in TheScientificWorld (01-01-2012)“…A simple, fast, and reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed and validated for determining of a cannabinoid…”
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13
The NANOGrav 11 yr Data Set: Evolution of Gravitational-wave Background Statistics
Published in The Astrophysical journal (20-02-2020)“…An ensemble of inspiraling supermassive black hole binaries should produce a stochastic background of very low frequency gravitational waves. This stochastic…”
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14
Diclofenac salts. I. Fractal and thermal analysis of sodium and potassium diclofenac salts
Published in Journal of pharmaceutical sciences (01-12-2001)“…Sodium and potassium diclofenac salts form hydrates when crystallized from water; the sodium salt contains four crystallization water molecules, while the…”
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15
Elaboration and "In Vitro" Characterization of 5-ASA Beads
Published in Drug development and industrial pharmacy (2005)“…The purpose of this research was to perform the design and in vitro evaluation of alginate beads containing 5-ASA in order to achieve an oral system that…”
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Role of Nanotechnology for Enzyme Replacement Therapy in Lysosomal Diseases. A Focus on Gaucher's Disease
Published in Current medicinal chemistry (01-01-2016)“…Lysosomal storage diseases (LSDs) comprise a group of rare inherited chronic syndromes that cause deficiency of specific native enzymes within the lysosomes…”
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In vitro evaluation of alginate beads of a diclofenac salt
Published in International journal of pharmaceutics (18-03-1998)“…Alginate beads containing diclofenac hydroxyethylpyrrolidine were formulated with either Eudragit or chitosan in order to achieve an enteric formulation. In…”
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Fractal analysis of beta-cyclodextrin-indomethacin particles compacted by ultrasound
Published in Journal of pharmaceutical sciences (01-11-1997)“…An association between indomethacin and beta-cyclodextrin (beta-CD) was obtained by compacting a 1:2 molar physical mixture by ultrasound. The product prepared…”
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Insulin-loaded PLGA microparticles: flow focusing versus double emulsion/solvent evaporation
Published in Journal of microencapsulation (01-08-2011)“…Context: Oral administration of insulin is severely limited by very low bioavailability. Biocompatible polymeric nanocarriers have been investigated to…”
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Effect of the temperature on a hydrate diclofenac salt
Published in International journal of pharmaceutics (20-04-1999)“…The salt Diclofenac/ N-(2-hydroxyethyl) pyrrolidine when crystallizes from water forms a di-hydrate, which looses the crystallization water molecules on…”
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