Search Results - "Holden, Rebecca L"

Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity by Backlund, Coralie M., Holden, Rebecca L., Moynihan, Kelly D., Garafola, Daniel, Farquhar, Charlotte, Mehta, Naveen K., Maiorino, Laura, Pham, Sydney, Iorgulescu, J. Bryan, Reardon, David A., Wu, Catherine J., Pentelute, Bradley L., Irvine, Darrell J.

“…Peptide-based cancer vaccines are widely investigated in the clinic but exhibit modest immunogenicity. One approach that has been explored to enhance peptide…”
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Perfluoroaryl Bicyclic Cell‐Penetrating Peptides for Delivery of Antisense Oligonucleotides by Wolfe, Justin M., Fadzen, Colin M., Holden, Rebecca L., Yao, Monica, Hanson, Gunnar J., Pentelute, Bradley L.

“…Exon‐skipping antisense oligonucleotides are effective treatments for genetic diseases, yet exon‐skipping activity requires that these macromolecules reach the…”
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Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery by Wolfe, Justin M., Fadzen, Colin M., Choo, Zi-Ning, Holden, Rebecca L., Yao, Monica, Hanson, Gunnar J., Pentelute, Bradley L.

“…Cell-penetrating peptides (CPPs) can facilitate the intracellular delivery of large therapeutically relevant molecules, including proteins and…”
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Colorimetric and longitudinal analysis of leukocoria in recreational photographs of children with retinoblastoma by Abdolvahabi, Alireza, Taylor, Brandon W, Holden, Rebecca L, Shaw, Elizabeth V, Kentsis, Alex, Rodriguez-Galindo, Carlos, Mukai, Shizuo, Shaw, Bryan F

“…Retinoblastoma is the most common primary intraocular tumor in children. The first sign that is often reported by parents is the appearance of recurrent…”
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Direct Measurement of Charge Regulation in Metalloprotein Electron Transfer by Zahler, Collin T., Zhou, Hongyu, Abdolvahabi, Alireza, Holden, Rebecca L., Rasouli, Sanaz, Tao, Peng, Shaw, Bryan F.

“…Determining whether a protein regulates its net electrostatic charge during electron transfer (ET) will deepen our mechanistic understanding of how…”
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Enhancement of Peptide Vaccine Immunogenicity by Increasing Lymphatic Drainage and Boosting Serum Stability by Moynihan, Kelly D, Holden, Rebecca L, Mehta, Naveen K, Wang, Chensu, Karver, Mark R, Dinter, Jens, Liang, Simon, Abraham, Wuhbet, Melo, Mariane B, Zhang, Angela Q, Li, Na, Gall, Sylvie Le, Pentelute, Bradley L, Irvine, Darrell J

“…Antitumor T-cell responses have the potential to be curative in cancer patients, but the induction of potent T-cell immunity through vaccination remains a…”
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Automated Flow Synthesis of Tumor Neoantigen Peptides for Personalized Immunotherapy by Truex, Nicholas L., Holden, Rebecca L., Wang, Bin-You, Chen, Pu-Guang, Hanna, Stephanie, Hu, Zhuting, Shetty, Keerthi, Olive, Oriol, Neuberg, Donna, Hacohen, Nir, Keskin, Derin B., Ott, Patrick A., Wu, Catherine J., Pentelute, Bradley L.

“…High-throughput genome sequencing and computation have enabled rapid identification of targets for personalized medicine, including cancer vaccines. Synthetic…”
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Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy by Fadzen, Colin M, Holden, Rebecca L, Wolfe, Justin M, Choo, Zi-Ning, Schissel, Carly K, Yao, Monica, Hanson, Gunnar J, Pentelute, Bradley L

“…Phosphorodiamidate morpholino oligonucleotides (PMOs) make up a promising class of therapeutics for genetic disease. PMOs designed for “exon skipping” must be…”
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Direct Measurement of Charge Regulation in Metalloprotein Electron Transfer by Zahler, Collin T., Zhou, Hongyu, Abdolvahabi, Alireza, Holden, Rebecca L., Rasouli, Sanaz, Tao, Peng, Shaw, Bryan F.

“…Determining whether a protein regulates its net electrostatic charge during electron transfer (ET) will deepen our mechanistic understanding of how…”
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Perfluoroaryl Bicyclic Cell‐Penetrating Peptides for Delivery of Antisense Oligonucleotides by Wolfe, Justin M., Fadzen, Colin M., Holden, Rebecca L., Yao, Monica, Hanson, Gunnar J., Pentelute, Bradley L.

“…Exon‐skipping antisense oligonucleotides are effective treatments for genetic diseases, yet exon‐skipping activity requires that these macromolecules reach the…”
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Inside Back Cover: Direct Measurement of Charge Regulation in Metalloprotein Electron Transfer (Angew. Chem. Int. Ed. 19/2018) by Zahler, Collin T., Zhou, Hongyu, Abdolvahabi, Alireza, Holden, Rebecca L., Rasouli, Sanaz, Tao, Peng, Shaw, Bryan F.

“…When a single electron is transferred to a protein, does the net charge of the protein change by one unit, or is charge regulation a dominant effect? Knowing…”
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Innenrücktitelbild: Direct Measurement of Charge Regulation in Metalloprotein Electron Transfer (Angew. Chem. 19/2018) by Zahler, Collin T., Zhou, Hongyu, Abdolvahabi, Alireza, Holden, Rebecca L., Rasouli, Sanaz, Tao, Peng, Shaw, Bryan F.

“…Was passiert beim Transfer eines einzelnen Elektrons auf ein Protein? Ändert sich die Gesamtladung um eine Einheit oder spielt Ladungsregulierung eine wichtige…”
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Innenrücktitelbild: Direct Measurement of Charge Regulation in Metalloprotein Electron Transfer by Zahler, Collin T, Zhou, Hongyu, Abdolvahabi, Alireza, Holden, Rebecca L, Rasouli, Sanaz, Peng, Tao, Shaw, Bryan F

“…Was passiert beim Transfer eines einzelnen Elektrons auf ein Protein? Ändert sich die Gesamtladung um eine Einheit oder spielt Ladungsregulierung eine wichtige…”
Get full text