Search Results - "Holden, K"

Evolution of diagnostic criteria and assessments for Parkinson's disease mild cognitive impairment by Goldman, Jennifer G., Holden, Samantha K., Litvan, Irene, McKeith, Ian, Stebbins, Glenn T., Taylor, John‐Paul

“…ABSTRACT Mild cognitive impairment has gained recognition as a construct and a potential prodromal stage to dementia in both Alzheimer's disease and…”
Get full text

Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling by Holden, Jeffrey K., Crawford, James J., Noland, Cameron L., Schmidt, Stephen, Zbieg, Jason R., Lacap, Jennifer A., Zang, Richard, Miller, Gregory M., Zhang, Yue, Beroza, Paul, Reja, Rohit, Lee, Wendy, Tom, Jeffrey Y.K., Fong, Rina, Steffek, Micah, Clausen, Saundra, Hagenbeek, Thjis J., Hu, Taishan, Zhou, Zheng, Shen, Hong C., Cunningham, Christian N.

“…The transcriptional enhanced associate domain (TEAD) family of transcription factors serves as the receptors for the downstream effectors of the Hippo pathway,…”
Get full text

Mortality Rate and Cause of Death in Adults with Extrapulmonary Nontuberculous Mycobacteria Infection, Denmark by Pedersen, Andreas A, Dahl, Victor N, Løkke, Anders, Holden, Inge K, Fløe, Andreas, Ibsen, Rikke, Hilberg, Ole, Johansen, Isik S

“…Evidence on mortality rates and causes of death associated with extrapulmonary nontuberculous mycobacteria (NTM) infection is limited. This nationwide…”
Get full text

Electrode modulated capacitance-electric field nonlinearity in metal-insulator-metal capacitors by Austin, D. Z., Holden, K. E. K., Hinz, J., Conley, J. F.

“…Metals with low enthalpy of oxide formation (ΔHox) are used to examine the influence of the metal/dielectric interface, in the absence of a significant…”
Get full text

Mycobacterium marinum infections in Denmark from 2004 to 2017: A retrospective study of incidence, patient characteristics, treatment regimens and outcome by Holden, Inge K., Kehrer, Michala, Andersen, Aase B., Wejse, Christian, Svensson, Erik, Johansen, Isik Somuncu

“…Mycobacterium marinum ( M. marinum ) is a slowly growing nontuberculous mycobacterium. The incidence of M. marinum infections in Denmark is unknown. We…”
Get full text

Original research: initial development of a pragmatic tool to estimate cognitive decline risk focusing on potentially modifiable factors in Parkinson’s disease by Carlisle, Tara C., Medina, Luis D., Holden, Samantha K.

“…IntroductionCognitive decline is common in Parkinson's disease (PD). Calculating personalized risk of cognitive decline in PD would allow for appropriate…”
Get full text

Integrative Biomarker Panel for Improved Lung Cancer Diagnosis Using Plasma microRNAs and Sputum Bacterial DNA by Dhilipkannah, Pushpa, Sachdeva, Ashutosh, Holden, Van K, Jiang, Feng

“…This study aimed to evaluate if integrating diverse molecular biomarkers in plasma and sputum could improve the diagnosis of lung cancer. The study analyzed…”
Get full text

Characteristics and predictors for tuberculosis related mortality in Denmark from 2009 through 2014: A retrospective cohort study by Holden, Inge K, Lillebaek, Troels, Andersen, Peter H, Wejse, Christian, Johansen, Isik S

“…Objectives Mortality from tuberculosis (TB) has been declining since 2000, nevertheless there is still a significant number of patients who die before or…”
Get full text

A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe by Marx-Stoelting, P., Rivière, G., Luijten, M., Aiello-Holden, K., Bandow, N., Baken, K., Cañas, A., Castano, A., Denys, S., Fillol, C., Herzler, M., Iavicoli, I., Karakitsios, S., Klanova, J., Kolossa-Gehring, M., Koutsodimou, A., Vicente, J. Lobo, Lynch, I., Namorado, S., Norager, S., Pittman, A., Rotter, S., Sarigiannis, D., Silva, M. J., Theunis, J., Tralau, T., Uhl, M., van Klaveren, J., Wendt-Rasch, L., Westerholm, E., Rousselle, C., Sanders, P.

“…Current approaches for the assessment of environmental and human health risks due to exposure to chemical substances have served their purpose reasonably well…”
Get full text

Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration by Gerhardy, Stefan, Ultsch, Mark, Tang, Wanjian, Green, Evan, Holden, Jeffrey K., Li, Wei, Estevez, Alberto, Arthur, Chris, Tom, Irene, Rohou, Alexis, Kirchhofer, Daniel

“…The trimeric serine protease HTRA1 is a genetic risk factor associated with geographic atrophy (GA), a currently untreatable form of age-related macular…”
Get full text

Microbiota Biomarkers for Lung Cancer by Leng, Qixin, Holden, Van K, Deepak, Janaki, Todd, Nevins W, Jiang, Feng

“…Non-small cell lung cancer (NSCLC) is the number one cancer killer and its early detection can reduce mortality. Accumulating evidences suggest an…”
Get full text

Posterior white matter integrity and self-reported posterior cortical symptoms using the Colorado Posterior Cortical Questionnaire by Holden, Samantha K, Bettcher, Brianne M, Filley, Christopher M, Lopez-Paniagua, Dan, Pelak, Victoria S

“…The Colorado Posterior Cortical Questionnaire (CPC-Q) is a self-report, 15-item screening questionnaire for posterior cortical symptoms, including visuospatial…”
Get full text

Humoral immune response following a third SARS-CoV-2 mRNA vaccine dose in solid organ transplant recipients compared with matched controls by Balsby, Daniel, Nilsson, Anna Christine, Petersen, Inge, Lindvig, Susan O, Davidsen, Jesper Rømhild, Abazi, Rozeta, Poulsen, Mikael K, Holden, Inge K, Justesen, Ulrik S, Bistrup, Claus, Johansen, Isik Somuncu

“…Solid organ transplant (SOT) recipients have shown suboptimal antibody response following COVID-19 vaccination. Several risk factors for the diminished…”
Get full text

A novel approach to understanding Parkinsonian cognitive decline using minimum spanning trees, edge cutting, and magnetoencephalography by Simon, Olivier B., Buard, Isabelle, Rojas, Donald C., Holden, Samantha K., Kluger, Benzi M., Ghosh, Debashis

“…Graph theory-based approaches are efficient tools for detecting clustering and group-wise differences in high-dimensional data across a wide range of fields,…”
Get full text

Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair by Perez-Bermejo, Juan A., Efagene, Oghene, Matern, William M., Holden, Jeffrey K., Kabir, Shaheen, Chew, Glen M., Andreoletti, Gaia, Catton, Eniola, Ennis, Craig L., Garcia, Angelica, Gerstenberg, Trevor L., Hill, Kaisle A., Jain, Aayami, Krassovsky, Kristina, Lalisan, Cassandra D., Lord, Daniel, Quejarro, B. Joy, Sales-Lee, Jade, Shah, Meet, Silva, Brian J., Skowronski, Jason, Strukov, Yuri G., Thomas, Joshua, Veraz, Michael, Vijay, Twaritha, Wallace, Kirby A., Yuan, Yue, Grogan, Jane L., Wienert, Beeke, Lahiri, Premanjali, Treusch, Sebastian, Dever, Daniel P., Soros, Vanessa B., Partridge, James R., Seim, Kristen L.

“…Homology Directed Repair (HDR) enables precise genome editing, but the implementation of HDR-based therapies is hindered by limited efficiency in comparison to…”
Get full text

Original research: longitudinal evaluation of cognitively demanding daily function using performance-based functional assessment highlights heterogeneous trajectories in cognitive and functional abilities in people with Parkinson's disease by Carlisle, Tara C, Fought, Angela J, Olson, Kaitlin E, Lopez-Esquibel, Natalie, Simpson, Abigail, Medina, Luis D, Holden, Samantha K

“…Longitudinal assessment of functional abilities in Parkinson's disease (PD) is needed to determine the efficacy of cognitive interventions in providing…”
Get full text

Review of tuberculosis treatment outcome reporting system in Denmark, a retrospective study cohort study from 2009 through 2014 by Holden, Inge K, Andersen, Peter H, Wejse, Christian, Lillebaek, Troels, Johansen, Isik S

“…In Denmark, reporting of tuberculosis (TB) treatment outcome is voluntary and data incomplete. In the European Centre for Disease Prevention and Control most…”
Get full text

Tap out: reducing waterborne Pseudomonas aeruginosa transmission in an intensive care unit by Garvey, M.I., Wilkinson, M.A.C., Holden, K.L., Martin, T., Parkes, J., Holden, E.

“…Pseudomonas aeruginosa is a ubiquitous and important opportunistic pathogen in immunocompromised or critically ill patients. Nosocomial P. aeruginosa outbreaks…”
Get full text

Equipment and procedural setup for interventional pulmonology procedures in the intensive care unit by Ray, Amrik S., Holden, Van K., Sachdeva, Ashutosh, Nasim, Faria

“…Procedural setup is an important aspect of any procedure. Interventional pulmonologists provide a procedural practice and have additional expertise in…”
Get full text

Autoantibodies against tumor-associated antigens in sputum as biomarkers for lung cancer by Li, Ning, Holden, Van K., Deepak, Janaki, Todd, Nevins W., Jiang, Feng

“…•It is important to develop biomarkers for the early detection of lung cancer.•By probing a protein microarray containing more than 9000 antigens with sputum…”
Get full text