Search Results - "Holcomb, J B"

The effect of FFP:RBC ratio on morbidity and mortality in trauma patients based on transfusion prediction score by Borgman, M. A., Spinella, P. C., Holcomb, J. B., Blackbourne, L. H., Wade, C. E., Lefering, R., Bouillon, B., Maegele, M.

“…Background and Objectives  The empiric use of a high plasma to packed red‐blood‐cell [fresh frozen plasma:red‐blood‐cells (FFP:RBC)] ratio in trauma…”
Get full text

Spray-dried plasma and fresh frozen plasma modulate permeability and inflammation in vitro in vascular endothelial cells by Wataha, K., Menge, T., Deng, X., Shah, A., Bode, A., Holcomb, J.B., Potter, D., Kozar, R., Spinella, P.C., Pati, S.

“…Background After major traumatic injury, patients often require multiple transfusions of fresh frozen plasma (FFP) to correct coagulopathy and to reduce…”
Get full text

Primary skin closure after damage control laparotomy by Pommerening, M. J., Kao, L. S., Sowards, K. J., Wade, C. E., Holcomb, J. B., Cotton, B. A.

“…Background Damage control laparotomy (DCL) is used widely in the management of patients with traumatic injuries but carries significant morbidity…”
Get full text

External validation of a smartphone app model to predict the need for massive transfusion using five different definitions by Hodgman, E I, Cripps, M W, Mina, M J, Bulger, E M, Schreiber, M A, Brasel, K J, Cohen, M J, Muskat, P, Myers, J G, Alarcon, L H, Rahbar, M H, Holcomb, J B, Cotton, B A, Fox, E E, Del Junco, D J, Wade, C E, Phelan, H A

“…Previously, a model to predict massive transfusion protocol (MTP) (activation) was derived using a single-institution data set. The PRospective, Observational,…”
Get full text

Associated injuries in casualties with traumatic lower extremity amputations caused by improvised explosive devices (Br J Surg 2012; 99: 362-366) by Holcomb, J. B.

Get full text

Transfusion practice in military trauma by Hess, J. R., Holcomb, J. B.

“…summary Modern warfare causes severe injuries, and despite rapid transportation to theater regional trauma centers, casualties frequently arrive coagulopathic…”
Get full text

A review of intraosseous vascular access : Current status and military application by DUBICK, M. A, HOLCOMB, J. B

“…Austere far-forward battlefield environments present numerous obstacles in providing adequate medical care to the injured solidier. In addition to logistical…”
Get full text

Military, civilian, and rural application of the damage control philosophy by HOLCOMB, John B, HELLING, Thomas S, HIRSHBERG, Asher

“…Damage control surgery is a useful salvage strategy for the most critically injured patients. Conceptually, this approach to individual patients can be…”
Get full text

Randomised controlled trial comparing marksmanship following application of a tourniquet or haemostatic clamp in healthy volunteers by LaPorta, Anthony, Kirkpatrick, A W, Mckee, J L, Roberts, D J, Tien, H, Beckett, A, Ball, C G, Mckee, I, Louw, D, Holcomb, J B

“…In a care under fire situation, a first line response to haemorrhage is to apply a tourniquet and return fire. However, there is little understanding of how…”
Get more information

Aerobic walking in slowly progressive neuromuscular disease: effect of a 12-week program by Wright, N C, Kilmer, D D, McCrory, M A, Aitkens, S G, Holcomb, B J, Bernauer, E M

“…Poor cardiorespiratory endurance is a common finding in neuromuscular disease (NMD), and the capacity of such patients to respond to aerobic training is…”
Get more information

Implications of new dry fibrin sealant technology for trauma surgery by Holcomb, J B, Pusateri, A E, Hess, J R, Hetz, S P, Harris, R A, Tock, B B, Drohan, W N, MacPhee, M J

“…Trauma patients have been bleeding to death for thousands of years. The methods used to control hemorrhage (tourniquets, pressure, bandages, and ligatures)…”
Get more information

Hospital trauma care in multiple-casualty incidents: A critical view by Hirshberg, Asher, Holcomb, John B., Mattox, Kenneth L.

“…During a multiple-casualty incident, a large casualty caseload adversely affects the quality of trauma care given to individual patients. From a trauma care…”
Get full text

Mortality from Isolated Civilian Penetrating Extremity Injury by Dorlac, W C., DeBakey, M E., Holcomb, J B., Fagan, S P., Kwong, K L., Dorlac, G R., Schreiber, M A., Persse, D E., Moore, F A., Mattox, K L.

“…BACKGROUND:Although studies have ascertained that ten percent of soldiers killed in battle bleed to death from extremity wounds, little data exists on…”
Get full text

Effect of fibrin bandage Fibrinogen concentration on blood loss after grade V liver injury in swine by PUSATERI, Anthony E, HOLCOMB, John B, HARRIS, Richard A, MACPHEE, Martin J, CHARLES, Nathaniel C, BEALL, L. Dawson, HESS, John R

“…To determine the effect of fibrinogen concentration of dry fibrin bandages on blood loss after grade V liver injury. Twenty-four pigs were used. Grade V liver…”
Get full text

Combined laparoscopic exploration and repair of inguinal hernias by HETZ, S. P, HOLCOMB, J. B

Get full text

Opposition Splint for Partial Thumb Amputation: A Case Study Measuring Disability before and after Splint Use by Dewey, W.S., PT, CHT, OCS, Richard, R.L., MS, PT, Hedman, T.L., DPT, OCS, Chapman, T.T., OTR/L, Quick, C.D., OTR/L, Renz, E.M., MD, Blackbourne, L.H., MD, Wolf, S.E., MD, Holcomb, J.B., MD

“…Abstract Study Design Case report. Introduction A combined burn and a partial amputation can be extremely debilitating as the thumb constitutes 40% of the…”
Get full text

Volumes and breathing patterns during speech in healthy and asthmatic subjects by Loudon, R G, Lee, L, Holcomb, B J

“…The lung volumes and ventilatory patterns used by 10 healthy subjects and 14 patients with varying degrees of asthma were studied. The protocol included…”
Get more information

Interleukin-6 Infusion Blunts Proinflammatory Cytokine Production Without Causing Systematic Toxicity in a Swine Model of Uncontrolled Hemorrhagic Shock by Brundage, Susan I., Zautke, N A., Holcomb, J B., Spain, D A., Lam, J C., Mastrangelo, M A., Macaitis, J M., Tweardy, D J.

“…BACKGROUND:Serum elevations of interleukin-6 (IL-6) correlate with multiple organ dysfunction syndrome and mortality in critically injured trauma patients…”
Get full text

Predictive model for survival at the conclusion of a damage control laparotomy by Aoki, Noriaki, Wall, Matthew J, Demsar, Janez, Zupan, Blaz, Granchi, Thomas, Schreiber, Martin A, Holcomb, John B, Byrne, Mike, Liscum, Kathleen R, Goodwin, Grady, Beck, J.Robert, Mattox, Kenneth L

“…Background: We employed modern statistical and data mining methods to model survival based on preoperative and intraoperative parameters for patients…”
Get full text

Implementation of Massive Transfusion Protocols in the United States: The Relationship Between Evidence and Practice by Chang, R., Holcomb, J. B.

Get full text