Search Results - "Holcomb, Henry H."

In Vivo Measurements of Glutamate, GABA, and NAAG in Schizophrenia by ROWLAND, Laura M, KONTSON, Kimberly, WEST, Jeffrey, EDDEN, Richard A, HE ZHU, ANDREA WIJTENBURG, S, HOLCOMB, Henry H, BARKER, Peter B

“…The major excitatory and inhibitory neurotransmitters, glutamate (Glu) and gamma-aminobutyric acid (GABA), respectively, are implicated in the pathophysiology…”
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A Test of the Cognitive Self-Medication Hypothesis of Tobacco Smoking in Schizophrenia by Hahn, Britta, Harvey, Alexander N, Concheiro-Guisan, Marta, Huestis, Marilyn A, Holcomb, Henry H, Gold, James M

“…Background Heavier tobacco smoking among people with schizophrenia (SCZ) has been suggested to reflect self-medication of cognitive deficits. The idea that…”
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Individualized Brain Inhibition and Excitation Profile in Response to Paired-Pulse TMS by Du, Xiaoming, Summerfelt, Ann, Chiappelli, Joshua, Holcomb, Henry H., Hong, L. Elliot

“…Short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF) are generated from paired-pulse transcranial magnetic stimulations (ppTMS)…”
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Neural Correlates of Motor Memory Consolidation by Shadmehr, Reza, Holcomb, Henry H.

“…Computational studies suggest that acquisition of a motor skill involves learning an internal model of the dynamics of the task, which enables the brain to…”
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Antipsychotic Drugs Alter Functional Connectivity between the Medial Frontal Cortex, Hippocampus, and Nucleus Accumbens as Measured by H215O PET by Bolding, Mark S, White, David M, Hadley, Jennifer A, Weiler, Martin, Holcomb, Henry H, Lahti, Adrienne C

“…To evaluate changes in functional connectivity as a result of treatment with antipsychotic drugs (APDs) in subjects with schizophrenia (SZ), we identified a…”
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Ketamine activates psychosis and alters limbic blood flow in schizophrenia by Lahti, A C, Holcomb, H H, Medoff, D R, Tamminga, C A

“…The non-competitive NMDA antagonist ketamine, given to schizophrenic individuals in subanesthetic doses, produced a short-lived, discrete activation of their…”
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The presence of absence : Habenular regulation of dopamine neurons and the encoding of negative outcomes by SHEPARD, Paul D, HOLCOMB, Henry H, GOLD, James M

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Modulation of Limbic Circuitry Predicts Treatment Response to Antipsychotic Medication: A Functional Imaging Study in Schizophrenia by Lahti, Adrienne C, Weiler, Martin A, Holcomb, Henry H, Tamminga, Carol A, Cropsey, Karen L

“…The regional neuronal changes taking place in the early and late stages of antipsychotic treatment are still not well characterized in humans. In addition, it…”
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Facilitation of relational learning in schizophrenia by Spieker, Elena A, Griego, Jacqueline A, Astur, Robert S, Holcomb, Henry H, Rowland, Laura M

“…Abnormal hippocampal function likely contributes to relational learning deficits observed in schizophrenia. It is unknown whether these deficits can be…”
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Correlations Between rCBF and Symptoms in Two Independent Cohorts of Drug-Free Patients with Schizophrenia by LAHTI, Adrienne C, WEILER, Martin A, HOLCOMB, Henry H, TAMMINGA, Carol A, CARPENTER, William T, MCMAHON, Robert

“…We report on the correlations between whole brain rCBF and the positive and negative symptoms of schizophrenia in two cohorts of patients who were scanned…”
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The interactive effects of ketamine and nicotine on human cerebral blood flow by Rowland, Laura M., Beason-Held, Lori, Tamminga, Carol A., Holcomb, Henry H.

“…Aim The purpose of this study was to determine if acute nicotine attenuated ketamine-induced regional cerebral blood flow (rCBF). Method Following 2–4 h of…”
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Effects of Noncompetitive NMDA Receptor Blockade on Anterior Cingulate Cerebral Blood Flow in Volunteers with Schizophrenia by HOLCOMB, Henry H, LAHTI, Adrienne C, MEDOFF, Deborah R, CULLEN, Tom, TAMMINGA, Carol A

“…Schizophrenia may be related to dysfunctional glutamatergic activity, specifically hypofunction of the N-methyl-D-aspartate receptor (NMDAR). In addition, it…”
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Anterior cingulate GABA levels predict whole-brain cerebral blood flow by Krause, Benjamin W, Wijtenburg, S Andrea, Holcomb, Henry H, Kochunov, Peter, Wang, Danny J J, Hong, L Elliot, Rowland, Laura M

“…This study examined the relationship of γ-aminobutyric acid (GABA) and glutamate levels from the anterior and posterior cingulates (AC and PC) with cerebral…”
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Probing the human hippocampus using rCBF: Contrasts in schizophrenia by Medoff, Deborah R., Holcomb, Henry H., Lahti, Adrienne C., Tamminga, Carol A.

“…Regional cerebral blood flow (rCBF) data from two PET‐15O water schizophrenia studies were analyzed using individually placed, magnetic resonance (MR)‐guided…”
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Functional effects of antipsychotic drugs: comparing clozapine with haloperidol by Lahti, Adrienne C, Holcomb, Henry H, Weiler, Martin A, Medoff, Deborah R, Tamminga, Carol A

“…Using positron emission tomography (PET) with 15O water, we compared regional cerebral blood flow (rCBF) patterns induced by clozapine or haloperidol in…”
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Genetic analysis of cortical thickness and fractional anisotropy of water diffusion in the brain by Kochunov, Peter, Glahn, David C, Nichols, Thomas E, Winkler, Anderson M, Hong, Elliot L, Holcomb, Henry H, Stein, Jason L, Thompson, Paul M, Curran, Joanne E, Carless, Melanie A, Olvera, Rene L, Johnson, Matthew P, Cole, Shelley A, Kochunov, Valeria, Kent, Jack, Blangero, John

“…The thickness of the brain's cortical gray matter (GM) and the fractional anisotropy (FA) of the cerebral white matter (WM) each follow an inverted U-shape…”
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Neural changes associated with relational learning in schizophrenia by Rowland, Laura M, Griego, Jacqueline A, Spieker, Elena A, Cortes, Carlos R, Holcomb, Henry H

“…Relational learning, which is learning the relationship among items, is impaired in schizophrenia but can be improved with training. This study investigated…”
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Successful learning in schizophrenia, functional neuroimaging studies, and theoretical considerations by Holcomb, Henry H, Murray, Graham K

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Poster #38 MRS STUDY OF GLUTAMATE, GABA, AND NAAG IN SCHIZOPHRENIA by Rowland, Laura M, Kontson, Kimberly, West, Jef T, Zhu, He, Edden, Richard A, Holcomb, Henry H, Barker, Peter B

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Sequential neural changes during motor learning in schizophrenia by Rowland, Laura M, Shadmehr, Reza, Kravitz, Dwight, Holcomb, Henry H

“…Abstract Positron emission tomography (PET) was used to investigate differences in neural plasticity associated with learning a unique motor task in patients…”
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