Search Results - "Holck, M"
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Arsenic in seafood is associated with increased thyroid-stimulating hormone (TSH) in healthy volunteers – A randomized controlled trial
Published in Journal of trace elements in medicine and biology (01-12-2017)“…•Organic arsenic from seafood increased plasma thyroid-stimulating hormone (TSH).•The increase in TSH was dose dependently associated with plasma…”
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Urinary excretion of arsenicals following daily intake of various seafoods during a two weeks intervention
Published in Food and chemical toxicology (01-04-2014)“…•Blue mussels intake for 15days resulted in concentrations of urinary methylarsonate (MA) of possible toxicological concern.•Intake of different seafood for…”
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Major and minor arsenic compounds accounting for the total urinary excretion of arsenic following intake of blue mussels (Mytilus edulis): A controlled human study
Published in Food and chemical toxicology (01-07-2012)“…► Bioconversion of arsenicals from blue mussels was studied in this controlled trial. ► Up to 17 different urinary arsenicals were identified. ► The minor As…”
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Humans seem to produce arsenobetaine and dimethylarsinate after a bolus dose of seafood
Published in Environmental research (01-01-2012)“…Seafood is the predominant food source of several organoarsenic compounds. Some seafood species, like crustaceans and seaweed, also contain inorganic arsenic…”
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1ISG-011 Development of a predictive model for estimating future drug expenses
Published in European journal of hospital pharmacy. Science and practice (01-03-2018)“…BackgroundDrug expenses are increasing. Especially novel drugs affect these expenses significantly and existing budgeting forecasts have hitherto not contained…”
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Purine nucleoside and nucleotide interactions on normal and subsensitive alpha adrenoreceptor responsiveness in guinea-pig vas deferens
Published in The Journal of pharmacology and experimental therapeutics (01-04-1978)“…Adenosine and adenosine 5'-monophosphate (AMP) augment contractile responses to norepinephrine (NE) in isolated guinea-pig vas deferens. Dipyridamole slightly…”
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Differential interactions of clonidine and methoxamine with the postsynaptic alpha-adrenoceptor of rabbit main pulmonary artery
Published in Journal of cardiovascular pharmacology (01-03-1983)“…We investigated the dependence upon extracellular Ca2+ of contractile responses of the isolated rabbit main pulmonary artery to the alpha-adrenoceptor…”
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Cardiovascular effects of the new angiotensin-converting-enzyme inhibitor, cilazapril, in anesthetized and conscious dogs
Published in Journal of cardiovascular pharmacology (01-01-1986)“…Cilazapril is a new angiotensin-converting-enzyme inhibitor. In conscious renal-hypertensive dogs, cilazapril (2 X 10 mg/kg/day p.o.) caused a long-lasting…”
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An angiotensin II antagonist with strongly prolonged action
Published in Biochemical and biophysical research communications (15-05-1989)“…A highly hydrophobic analogue of angiotensin II (AT), [Sar1,(2',3',4',5',6'-Br5)Phe8]AT exhibited strong and persistent specific antagonism against AT, both in…”
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Effects of chronic myocardial infarction on responsiveness to isoprenaline and the state of myocardial beta adrenoceptors in rats
Published in Cardiovascular research (01-09-1987)“…Responsiveness to catecholamines and alterations in myocardial beta adrenoceptors were determined in rats with chronic myocardial infarction. Myocardial…”
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OC-0759 Shared Decision Making with breast cancer patients - does it work? The randomized DBCG RT SDM trial
Published in Radiotherapy and oncology (01-05-2023)Get full text
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Inhibition of myocardial Ca2+ channels by three dihydropyridines with different structural features: potential‐dependent blockade by Ro 18–3981
Published in British journal of pharmacology (01-05-1987)“…1 Inhibition of myocardial Ca2+ channels was investigated for three dihydropyridines with different structural features: Ro 18–3981, darodipine (PY 108‐068)…”
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o-Isothiocyanate dihydropyridine (oNCS-DHP), a long-acting, reversible inhibitor of the Ca++ channel
Published in The Journal of pharmacology and experimental therapeutics (01-09-1986)“…The binding characteristics and pharmacological properties of o-isothiocyanate dihydropyridine [oNCS-DHP;…”
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Inhibition of the myocardial Ca2+ inward current by the class 1 antiarrhythmic agent, cibenzoline
Published in British journal of pharmacology (01-04-1986)“…1 Cibenzoline, a class 1 (local anaesthetic‐type) antiarrhythmic drug, was investigated for possible effects upon the myocardial Ca2+ inward current. 2 In…”
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An angiotensin with prolonged action and blood pressure--lowering properties
Published in Journal of cardiovascular pharmacology (1990)“…[Sar1,Phe(Br5)8] angiotensin II (Br5Ang II) is a specific, quasi-irreversible antagonist of angiotensin II (Ang II) in vitro. In vivo, this compound is a very…”
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Chronic administration of tiapamil prevents hemodynamic alterations accompanying development of high blood pressure in hypertensive rats
Published in Journal of cardiovascular pharmacology (01-11-1984)“…Daily oral administration of tiapamil (2 X 50-2 X 150 mg/kg, for 13 weeks) to spontaneously hypertensive rats (SHR) resulted in a dose-dependent inhibition of…”
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PD-0740 Danish Breast Cancer Group Skagen Trial 1: A report on annual trial participation
Published in Radiotherapy and oncology (01-05-2022)Get full text
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An opioid agonist with preference for kappa-opioid receptors: (-)-N-cyclopropylmethylmorphinan-6-one
Published in Archiv der Pharmazie (Weinheim) (01-01-1990)“…N-Cyclopropylmethyl- and N-cyclobutylmethylmorphinan-6-one (3 and 4, respectively) were prepared from N-methylmorphinan-6-one. The pharmacological studies…”
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Does [3H]nifedipine label the calcium channel in rabbit myocardium?
Published in Journal of receptor research (1983)“…The ionic and drug specificities of the [3H]nifedipine binding site in rabbit cardiac homogenates were investigated. Divalent cations inhibited specific…”
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