Search Results - "Holay, Namit"

Sharpening the Edge for Precision Cancer Immunotherapy: Targeting Tumor Antigens through Oncolytic Vaccines by Holay, Namit, Kim, Youra, Lee, Patrick, Gujar, Shashi

“…Cancer immunotherapy represents a promising, modern-age option for treatment of cancers. Among the many immunotherapies being developed, oncolytic viruses…”
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After virus exposure, early bystander naïve CD8 T cell activation relies on NAD + salvage metabolism by Holay, Namit, Kennedy, Barry E, Murphy, J Patrick, Konda, Prathyusha, Giacomantonio, Michael, Brauer-Chapin, Tatjana, Paulo, Joao A, Kumar, Vishnupriyan, Kim, Youra, Elaghil, Mariam, Sisson, Gary, Clements, Derek, Richardson, Christopher, Gygi, Steven P, Gujar, Shashi

“…CD8 T cells play a central role in antiviral immunity. Type I interferons are among the earliest responders after virus exposure and can cause extensive…”
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Inhibition of Pyruvate Dehydrogenase Kinase Enhances the Antitumor Efficacy of Oncolytic Reovirus by Kennedy, Barry E, Murphy, John Patrick, Clements, Derek R, Konda, Prathyusha, Holay, Namit, Kim, Youra, Pathak, Gopal P, Giacomantonio, Michael A, Hiani, Yassine El, Gujar, Shashi

“…Oncolytic viruses (OV) such as reovirus preferentially infect and kill cancer cells. Thus, the mechanisms that dictate the susceptibility of cancer cells to…”
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Quantitative Temporal in Vivo Proteomics Deciphers the Transition of Virus-Driven Myeloid Cells into M2 Macrophages by Clements, Derek R, Murphy, John Patrick, Sterea, Andra, Kennedy, Barry E, Kim, Youra, Helson, Erin, Almasi, Shekoufeh, Holay, Namit, Konda, Prathyusha, Paulo, Joao A, Sharif, Tanveer, Lee, Patrick W, Weekes, Michael P, Gygi, Steven P, Gujar, Shashi

“…Myeloid cells play a central role in the context of viral eradication, yet precisely how these cells differentiate throughout the course of acute infections is…”
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