Search Results - "Hokka, C.O"

Modelling and optimization of the cephalosporin C production bioprocess in a fed-batch bioreactor with invert sugar as substrate by Cruz, A.J.G., Silva, A.S., Araujo, M.L.G.C., Giordano, R.C., Hokka, C.O.

“…Cephalosporin C production process optimization was studied based on four experiments carried out in an agitated and aerated tank fermentor operated as a…”
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Effect of different carbon and nitrogen sources on Streptomyces clavuligerus metabolism for clavulanic acid and cephamycin C production by Oliveira, L.M., Cruz, A.J.G., Hokka, C.O.

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43. Marine Streptomyces acrimycini and S. cebimarensis can produce cytotoxic activity on cells HCT-8 and SF295 by Romano, L.H., Granato, A.C., Montenegro, R., Hokka, C.O., Badino-Junior, A.C., Paiva de Sousa, C.

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Utilization of soybean derivatives on clavulanic acid production by Streptomyces clavuligerus by Ortiz, S.C.A., Hokka, C.O., Badino, A.C.

“…The influence of the type of soybean derivatives as nitrogen sources, as well as the simultaneous influence of the concentrations of nitrogen and carbon…”
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Separation of clavulanic acid from fermented broth of amino acids by an aqueous two-phase system and ion exchange adsorption by Barboza, M., Silva, C., Cuel, M., Barreto, V., Hokka, C.O.

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Erratum to “Effects of glucose and inoculum concentrations on production of bioactive molecules by Paenibacillus polymyxa RNC-D: A statistical experimental design” [J. Biotechnol. 150S (2010) S524] by Serrano, N.F.G., Mussatto, S.I., Rodrigues, L.R., Teixeira, J.A., Hokka, C.O., Sousa, C.P.

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Optimization of clavulanic acid precipitation reactions by Hirata, D.B., Oliveira, J.H.L., Leão, K., Ferreirra, A.G., Giulietti, M., Rodrigues, M.I., Barboza, M., Hokka, C.O.

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Precipitation of clavulanic acid from fermentation broth with potassium 2-ethyl hexanoate salt by Hirata, D.B., Oliveira, J.H.H.L., Leão, K.V., Rodrigues, M.I., Ferreira, A.G., Giulietti, M., Barboza, M., Hokka, C.O.

“…This paper describes a direct precipitation reaction of clavulanic acid (CA) using potassium 2-ethyl hexanoate salt. Clavulanic acid is an important molecule…”
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Estimation of intrinsic kinetic parameters in immobilised cell systems for anaerobic wastewater treatment by VIEIRA, L. G. T, ZAIAT, M, FORESTI, E, HOKKA, C. O

“…The intrinsic kinetic parameters (maximal specific substrate utilization rate and half velocity coefficient) were determined for an anaerobic sludge…”
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Effects of glucose and inoculum concentrations on production of bioactive molecules by Paenibacillus polymyxa RNC-D: A statistical experimental design by Serrano, N.F.G., Mussato, S.I., Rodrigues, L.R., Teixeira, J.A., Hokka, C.O., Sousa, C.P.

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Influence of temperature on the kinetics of adsorption and desorption of clavulanic acid by ionic exchange by Barboza, Marlei, Almeida, Renata M.R.G., Hokka, Carlos.O.

“…Beta-lactamases are enzymes that deactivate penicillins and cephalosporins by hydrolyzing their beta-lactam rings, producing penicilloic acid derivatives and,…”
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Utilization of vegetable oil in the production of clavulanic acid by Streptomyces clavuligerus ATCC 27064 by Maranesi, G.L, Baptista-Neto, A, Hokka, C.O, Badino, A.C

“…Production of clavulanic acid (CA) by Streptomyces clavuligerus ATCC 27064 in shake-flask culture (28 degree C, 250 rev min super(-1)) was evaluated, with…”
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Cephalosporin C production by immobilized Cephalosporium acremonium cells in a repeated batch tower bioreactor by Cruz, Antonio J. G., Pan, Tai, Giordano, Roberto C., Araujo, Maria Lucia G. C., Hokka, Carlos O.

“…The industrial production of antibiotics with filamentous fungi is usually carried out in conventional aerated and agitated tank fermentors. Highly viscous…”
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Optimisation of medium composition for clavulanic acid production by Streptomyces clavuligerus by GOUVEIA, Ester R, BAPTISTA, Alvaro NETO, BADINO, Alberto C, HOKKA, Carlos O

“…Among four different commercially available nitrogen sources containing soybean derivatives, a protein extract of soybean gave the highest yield for clavulanic…”
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Continuous cephalosporin C purification: dynamic modelling and parameter validation by BARBOZA, M, HOKKA, C. O, MAUGERI, F

“…A mathematical kinetic model for the adsorption and desorption of cephalosporin C on Amberlite XAD-2 resin is proposed. The model can represent Langmuir,…”
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The dead core model applied to beads with immobilized cells in a fed-batch cephalosporin C production bioprocess by Cruz, A.J.G., Almeida, R.M.R.G., Araujo, M.L.G.C., Giordano, R.C., Hokka, C.O.

“…Viable cells immobilized in inert supports are currently studied for a wide range of bioprocesses. The intrinsic advantages of such systems over suspended…”
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Studies on the respiration rate of free and immobilized cells of Cephalosporium acremonium in cephalosporin C production by Araujo, M. L. G. C., Giordano, R. C., Hokka, C. O.

“…Bioprocesses using filamentous fungi immobilized in inert supports present many advantages when compared to conventional free cell processes. However,…”
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General relationship for volumetric oxygen transfer coefficient ( kLa) prediction in tower bioreactors utilizing immobilized cells by Barboza, M., Zaiat, M., Hokka, C. O.

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hybrid neural network algorithm for on-line state inference that accounts for differences in inoculum of Cephalosporium acremonium in fed-batch fermentors by Silva, R.G, Cruz, A.J.G, Hokka, C.O, Giordano, R.L.C, Giordano, R.C

“…One serious difficulty in modeling a fermentative process is the forecasting of the duration of the lag phase. The usual approach to model biochemical reactors…”
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Comparative studies on cephalosporin C production process with free and immobilized cells of Cephalosporium acremonium ATCC 48272 by Araujo, M.L.G.C., Oliveira, R.P., Giordano, R.C., Hokka, C.O.

“…Immobilized cell utilization in tower type bioreactor is being studied extensively as a promising alternative for industrial bioprocess. In the cephalosporin C…”
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