Search Results - "Hojo, T."

FcγR2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer by Tamura, K., Shimizu, C., Hojo, T., Akashi-Tanaka, S., Kinoshita, T., Yonemori, K., Kouno, T., Katsumata, N., Ando, M., Aogi, K., Koizumi, F., Nishio, K., Fujiwara, Y.

“…Antibody-dependent-mediated cytotoxicity (ADCC) is one of the modes of action for trastuzumab. Recent data have suggested that fragment C γ receptor (FcγR)…”
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Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients by Collares, Cristhianna V A, Evangelista, Adriane F, Xavier, Danilo J, Rassi, Diane M, Arns, Thais, Foss-Freitas, Maria C, Foss, Milton C, Puthier, Denis, Sakamoto-Hojo, Elza T, Passos, Geraldo A, Donadi, Eduardo A

“…Regardless the regulatory function of microRNAs (miRNA), their differential expression pattern has been used to define miRNA signatures and to disclose disease…”
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Conscious sedation with midazolam intravenously for a patient with Parkinson’s disease and unpredictable chorea-like dyskinesia by Shibuya, M., Hojo, T., Hase, Y., Fujisawa, T.

“…Oral surgery can be difficult in patients with chorea-like dyskinesia, which is common in those on long-term levodopa medication for Parkinson’s disease, and…”
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Concomitant formation of different nature clusters and hardening in reactor pressure vessel steels irradiated by heavy ions by Fujii, K., Fukuya, K., Hojo, T.

“…Specimens of A533B steels containing 0.04, 0.09 and 0.21wt%Cu were irradiated at 290°C to 3dpa with 3MeV Fe ions and subjected to atom probe analyses,…”
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From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease by Chierrito, Talita P.C., Pedersoli-Mantoani, Susimaire, Roca, Carlos, Requena, Carlos, Sebastian-Perez, Victor, Castillo, Willian O., Moreira, Natalia C.S., Pérez, Concepción, Sakamoto-Hojo, Elza T., Takahashi, Catarina S., Jiménez-Barbero, Jesús, Cañada, F. Javier, Campillo, Nuria E., Martinez, Ana, Carvalho, Ivone

“…The lack of an effective treatment for Alzheimer’ disease (AD), an increasing prevalence and severe neurodegenerative pathology boost medicinal chemists to…”
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Multicenter study to evaluate the efficacy and standardize radiofrequency ablation therapy for early breast cancer (RAFAELO study) by Kinoshita, T., Ohtani, S., Doihara, H., Takahashi, M., Fujisawa, T., Yamamoto, N., Aogi, K., Hojo, T.

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Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice by Fornari, Thais A, Donate, Paula B, Assis, Amanda F, Macedo, Claudia, Sakamoto-Hojo, Elza T, Donadi, Eduardo A, Passos, Geraldo A

“…In autoimmune type 1 diabetes mellitus (T1D), auto-reactive clones of CD4+ and CD8+ T lymphocytes in the periphery evolve into pancreas-infiltrating T…”
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A phase III study comparing trastuzumab emtansine with trastuzumab, pertuzumab, and docetaxel in elderly patients with advanced stage HER2-positive breast cancer (JCOG1607 HERB TEA study) by Shimomura, A., Tamura, K., Mizutani, T., Shibata, T., Hara, F., Fujisawa, T., Niikura, N., Hojo, T., Kambayashi, C., Saji, S., Masuda, N., Sawaki, M., Yamamoto, N., Nagashima, F., Shien, T., Iwata, H.

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Gene expression profiles displayed by peripheral blood mononuclear cells from patients with type 2 diabetes mellitus focusing on biological processes implicated on the pathogenesis of the disease by Manoel-Caetano, Fernanda S., Xavier, Danilo J., Evangelista, Adriane F., Takahashi, Paula, Collares, Cristhianna V., Puthier, Denis, Foss-Freitas, Maria C., Foss, Milton C., Donadi, Eduardo A., Passos, Geraldo A., Sakamoto-Hojo, Elza T.

“…Patients with type 2 diabetes mellitus (T2DM) exhibit insulin resistance associated with obesity and inflammatory response, besides an increased level of…”
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Transcript Expression Profiles and MicroRNA Regulation Indicate an Upregulation of Processes Linked to Oxidative Stress, DNA Repair, Cell Death, and Inflammation in Type 1 Diabetes Mellitus Patients by Takahashi, Paula, Xavier, Danilo J., Lima, Jessica E. B. F., Evangelista, Adriane F., Collares, Cristhianna V. A., Foss-Freitas, Maria C., Rassi, Diane M., Donadi, Eduardo A., Passos, Geraldo A., Sakamoto-Hojo, Elza T.

“…Type 1 diabetes (T1D) arises from autoimmune-mediated destruction of insulin-producing β-cells leading to impaired insulin secretion and hyperglycemia. T1D is…”
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Autoimmune regulator (Aire) controls the expression of microRNAs in medullary thymic epithelial cells by Macedo, Claudia, Evangelista, Adriane F, Marques, Márcia M, Octacílio-Silva, Shirlei, Donadi, Eduardo A, Sakamoto-Hojo, Elza T, Passos, Geraldo A

“…Abstract The autoimmune regulator (Aire) is a transcription factor that controls the ectopic expression of a large set of peripheral tissue antigen (PTA) genes…”
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Aire Downregulation Is Associated with Changes in the Posttranscriptional Control of Peripheral Tissue Antigens in Medullary Thymic Epithelial Cells by Oliveira, Ernna H, Macedo, Claudia, Collares, Cristhianna V, Freitas, Ana Carolina, Donate, Paula Barbim, Sakamoto-Hojo, Elza T, Donadi, Eduardo A, Passos, Geraldo A

“…Autoimmune regulator (Aire) is a transcriptional regulator of peripheral tissue antigens (PTAs) and microRNAs (miRNAs) in medullary thymic epithelial cells…”
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P313 A new predictive score for axillary lymph node metastases in breast cancer patients by Ogura, T, Kinoshita, T, Jimbo, K, Asaga, S, Hojo, T

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E2F transcription factors associated with up-regulated genes in glioblastoma by Donaires, Flávia S, Godoy, Paulo R D V, Leandro, Giovana S, Puthier, Denis, Sakamoto-Hojo, Elza T

“…Glioblastoma is considered to the most common and malignant brain tumor in adults. Patients have a median survival of approximately one year from diagnosis due…”
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T cell post-transcriptional miRNA-mRNA interaction networks identify targets associated with susceptibility/resistance to collagen-induced arthritis by Donate, Paula B, Fornari, Thais A, Macedo, Claudia, Cunha, Thiago M, Nascimento, Daniele C B, Sakamoto-Hojo, Elza T, Donadi, Eduardo A, Cunha, Fernando Q, Passos, Geraldo A

“…Due to recent studies indicating that the deregulation of microRNAs (miRNAs) in T cells contributes to increased severity of rheumatoid arthritis, we…”
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539 A New Development in Sentinel Lymph Node Biopsy in Breast Cancer Using a Combination of Molecular and Histological Methods by Jimbo, K, Kinoshita, T, Hojo, T, Asaga, S, Suzuki, J

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41. A multi-center prospective study of radiofrequency ablation without surgical excision for small breast carcinomas by Kinoshita, T, Doihara, H, Yamamoto, N, Fujisawa, T, Takahashi, M, Aogi, K, Tsuda, H, Yoshida, M, Hojo, T, Jimbo, K, Asaga, S, Takayama, S

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ABCB1 C3435T polymorphism influences methotrexate sensitivity in rheumatoid arthritis patients by TAKATORI, R, TAKAHASHI, K. A, TANAKA, T, HIROTA, Y, KUBO, T, TOKUNAGA, D, HOJO, T, FUJIOKA, M, ASANO, T, HIRATA, T, KAWAHITO, Y, SATOMI, Y, NISHINO, H

“…Methotrexate (MTX) is most widely used for the treatment of rheumatoid arthritis (RA). However, it has certain drawbacks with regard to individual differences…”
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Lymphocytes of patients with Alzheimer's disease display different DNA damage repair kinetics and expression profiles of DNA repair and stress response genes by Leandro, Giovana S, Lobo, Romulo R, Oliveira, Douglas V N P, Moriguti, Julio C, Sakamoto-Hojo, Elza T

“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder, characterized by loss of memory and cognitive capacity. Given the limitations to analyze…”
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Mechanisms underlying the pathophysiology of type 2 diabetes: From risk factors to oxidative stress, metabolic dysfunction, and hyperglycemia by Lima, Jessica E.B.F., Moreira, Natalia C.S., Sakamoto-Hojo, Elza T.

“…•Redox imbalance and oxidative stress are implicated in Type 2 diabetes pathogenesis.•Type 2 diabetes development involves a vicious cycle of complex metabolic…”
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