Search Results - "Hojnacki, Taylor"
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Coaxial nanofiber scaffold with super-active platelet lysate to accelerate the repair of bone defects
Published in RSC advances (29-09-2020)“…To develop biocomposite materials with the local sustained-release function of biological factors to promote bone defect repair, coaxial electrospinning…”
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Menin Maintains Cholesterol Content in Colorectal Cancer via Repression of LXR-Mediated Transcription
Published in Cancers (16-08-2023)“…Menin is a nuclear scaffold protein that regulates gene transcription in an oftentimes tissue-specific manner. Our previous work showed that menin is…”
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Menin‐regulated Pbk controls high fat diet‐induced compensatory beta cell proliferation
Published in EMBO molecular medicine (07-05-2021)“…Pancreatic beta cells undergo compensatory proliferation in the early phase of type 2 diabetes. While pathways such as FoxM1 are involved in regulating…”
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Menin: Expanding and dichotomous roles in cancer
Published in Oncoscience (23-08-2019)Get full text
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Prolactin-regulated Pbk is involved in pregnancy-induced β-cell proliferation in mice
Published in Journal of endocrinology (01-02-2022)“…Gestational diabetes mellitus (GDM) is a condition of diabetes with onset or first recognition in pregnancy. Its incidence is increasing, and GDM deleteriously…”
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Menin-mediated Repression of Glycolysis in Combination with Autophagy Protects Colon Cancer Against Small-molecule EGFR Inhibitors
Published in Molecular cancer therapeutics (01-11-2020)“…Menin serves both tumor suppressor and promoter roles in a highly tumor-specific manner. In colorectal cancer, menin is overexpressed and plays a critical role…”
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Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues
Published in Nature cancer (01-05-2022)“…Gastrointestinal cancers (GICs) and neuroendocrine tumors (NETs) are often refractory to therapy after metastasis. Adoptive cell therapy using chimeric antigen…”
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Disruption of the menin-MLL interaction triggers menin protein degradation via ubiquitin-proteasome pathway
Published in American journal of cancer research (01-01-2019)“…Menin, a protein encoded by the gene, suppresses cancers associated with multiple endocrine neoplasia type 1 (MEN1), but promotes the development of a subset…”
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Author Correction: Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues
Published in Nature cancer (11-04-2024)Get full text
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