Search Results - "Hojjat Farsangi, Mohammad"

Adenosine and adenosine receptors in the immunopathogenesis and treatment of cancer by Kazemi, Mohammad H., Raoofi Mohseni, Sahar, Hojjat‐Farsangi, Mohammad, Anvari, Enayat, Ghalamfarsa, Ghasem, Mohammadi, Hamed, Jadidi‐Niaragh, Farhad

“…Tumor cells overcome anti‐tumor responses in part through immunosuppressive mechanisms. There are several immune modulatory mechanisms. Among them, adenosine…”
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The imbalance of Th17/Treg axis involved in the pathogenesis of preeclampsia by Eghbal‐Fard, Shadi, Yousefi, Mehdi, Heydarlou, Hanieh, Ahmadi, Majid, Taghavi, Simin, Movasaghpour, Aliakbar, Jadidi‐Niaragh, Farhad, Yousefi, Bahman, Dolati, Sanam, Hojjat‐Farsangi, Mohammad, Rikhtegar, Reza, Nouri, Mohammad, Aghebati‐Maleki, Leili

“…Problem Inappropriate activation of the immune system, particularly the imbalance of T‐helper type 17 (Th17)/regulatory T (Treg) cells is thought to play…”
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Berberine: A novel therapeutic strategy for cancer by Samadi, Parisa, Sarvarian, Parisa, Gholipour, Elham, Asenjan, Karim Shams, Aghebati‐Maleki, Leili, Motavalli, Roza, Hojjat‐Farsangi, Mohammad, Yousefi, Mehdi

“…Cancer, even currently, is one of the main reasons for mortality and morbidity, worldwide. In recent years, a great deal of effort has been made to find…”
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Blockage of immune checkpoint molecules increases T‐cell priming potential of dendritic cell vaccine by Hassannia, Hadi, Ghasemi Chaleshtari, Mitra, Atyabi, Fatemeh, Nosouhian, Mahshid, Masjedi, Ali, Hojjat‐Farsangi, Mohammad, Namdar, Afshin, Azizi, Gholamreza, Mohammadi, Hamed, Ghalamfarsa, Ghasem, Sabz, Gholamabas, Hasanzadeh, Sajad, Yousefi, Mehdi, Jadidi‐Niaragh, Farhad

“…Summary Dendritic cell (DC) ‐based cancer immunotherapy is one of the most important anti‐cancer immunotherapies, and has been associated with variable…”
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Altered T‐cell subpopulations in recurrent pregnancy loss patients with cellular immune abnormalities by Abdolmohammadi Vahid, Samaneh, Ghaebi, Mahnaz, Ahmadi, Majid, Nouri, Mohammad, Danaei, Shahla, Aghebati‐Maleki, Leili, Mousavi Ardehaie, Reza, Yousefi, Bahman, Hakimi, Parvin, Hojjat‐Farsangi, Mohammad, Rikhtegar, Reza, Yousefi, Mehdi

“…Recurrent pregnancy loss (RPL) is a multifactorial disorder of women in reproductive age, which in some cases is caused by immunologic abnormalities. In this…”
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The role of DEAD‐box RNA helicase p68 (DDX5) in the development and treatment of breast cancer by Hashemi, Vida, Masjedi, Ali, Hazhir‐karzar, Bita, Tanomand, Asghar, Shotorbani, Siamak Sandoghchian, Hojjat‐Farsangi, Mohammad, Ghalamfarsa, Ghasem, Azizi, Gholamreza, Anvari, Enayat, Baradaran, Behzad, Jadidi‐Niaragh, Farhad

“…RNA helicase p68 or DEAD (Asp‐Glu‐Ala‐Asp) box polypeptide 5 (DDX5) is a unique member of the highly conserved protein family, which is involved in a broad…”
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T‐cell immunoglobulin and ITIM domain, as a potential immune checkpoint target for immunotherapy of colorectal cancer by Fathi, Mehrdad, Pustokhina, Inna, Kuznetsov, Sergey V., Khayrullin, Mars, Hojjat‐Farsangi, Mohammad, Karpisheh, Vahid, Jalili, Ali, Jadidi‐Niaragh, Farhad

“…The importance of the tumor microenvironment in cancer progression has been well studied for many years. Immune checkpoint inhibitors (ICIs) are regarded as…”
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Dimethyl fumarate: Regulatory effects on the immune system in the treatment of multiple sclerosis by Hosseini, Arezoo, Masjedi, Ali, Baradaran, Behzad, Hojjat‐Farsangi, Mohammad, Ghalamfarsa, Ghasem, Anvari, Enayat, Jadidi‐Niaragh, Farhad

“…Dimethyl fumarate (DMF) is an important oral treatment option for various autoimmune diseases, such as multiple sclerosis (MS) and psoriasis. DMF and its…”
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Anti‐angiogenic effects of CD73‐specific siRNA‐loaded nanoparticles in breast cancer‐bearing mice by Ghalamfarsa, Ghasem, Rastegari, Ali, Atyabi, Fatemeh, Hassannia, Hadi, Hojjat‐Farsangi, Mohammad, Ghanbari, Amir, Anvari, Enayat, Mohammadi, Jamshid, Azizi, Gholamreza, Masjedi, Ali, Yousefi, Mehdi, Yousefi, Bahman, Hadjati, Jamshid, Jadidi‐Niaragh, Farhad

“…CD73 facilitates tumor growth by upregulation of the adenosine (immunosuppressive factor) in the tumor microenvironment, however, its precise molecular…”
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Smac mimetics as novel promising modulators of apoptosis in the treatment of breast cancer by Nikkhoo, Afshin, Rostami, Narges, Hojjat‐Farsangi, Mohammad, Azizi, Gholamreza, Yousefi, Bahman, Ghalamfarsa, Ghasem, Jadidi‐Niaragh, Farhad

“…Breast cancer is the most prevalent cancer in women. Despite improvements in treatment, the rate of breast cancer‐related deaths is still high, and this issue…”
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Metabolic syndrome mediates proinflammatory responses of inflammatory cells in preeclampsia by Jabalie, Gisoo, Ahmadi, Majid, Koushaeian, Ladan, Eghbal‐Fard, Shadi, Mehdizadeh, Amir, Kamrani, Amin, Abdollahi‐Fard, Sedigheh, Farzadi, Laya, Hojjat‐ Farsangi, Mohammad, Nouri, Mohammad, Yousefi, Mehdi

“…Problem To investigate whether metabolic syndrome (MetS) is associated with exacerbation of inflammatory responses in preeclamptic (PE) patients, the dynamic…”
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Concomitant blockade of A2AR and CTLA‐4 by siRNA‐loaded polyethylene glycol‐chitosan‐alginate nanoparticles synergistically enhances antitumor T‐cell responses by Ghasemi‐Chaleshtari, Mitra, Kiaie, Seyed Hossein, Irandoust, Mahzad, Karami, Hadis, Nabi Afjadi, Mohsen, Ghani, Sepideh, Aghaei Vanda, Nasimeh, Ghaderi Sede, Mohammad Javad, Ahmadi, Armin, Masjedi, Ali, Hassannia, Hadi, Atyabi, Fatemeh, Hojjat‐Farsangi, Mohammad, Namdar, Afshin, Ghalamfarsa, Ghasem, Jadidi‐Niaragh, Farhad

“…Inhibitory immune checkpoint (ICP) molecules are important immunosuppressive factors in a tumor microenvironment (TME). They can robustly suppress…”
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The role of SF3B1 and NOTCH1 in the pathogenesis of leukemia by Abolhasani, Shiva, Hejazian, Seyyed Sina, Karpisheh, Vahid, Khodakarami, Atefeh, Mohammadi, Hamed, Gholizadeh Navashenaq, Jamshid, Hojjat‐Farsangi, Mohammad, Jadidi‐Niaragh, Farhad

“…The discovery of new genes/pathways improves our knowledge of cancer pathogenesis and presents novel potential therapeutic options. For instance, splicing…”
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Promising immunotherapy: Highlighting cytokine‐induced killer cells by Shirjang, Solmaz, Alizadeh, Nazila, Mansoori, Behzad, Mahmoodpoor, Ata, Kafil, Hossein Samadi, Hojjat‐Farsangi, Mohammad, Yousefi, Mehdi

“…For many years, cancer therapy has appeared to be a challenging issue for researchers and physicians. By the introduction of novel methods in immunotherapy,…”
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Predicting ROR1/BCL2 combination targeted therapy of small cell carcinoma of the lung by Wang, Walter Z., Shilo, Konstantin, Amann, Joseph M., Shulman, Alyssa, Hojjat-Farsangi, Mohammad, Mellstedt, Håkan, Schultz, Johan, Croce, Carlo M., Carbone, David P.

“…Small cell lung cancer (SCLC) remains a deadly form of cancer, with a 5-year survival rate of less than 10 percent, necessitating novel therapies. Receptor…”
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Small-molecule inhibitors of the receptor tyrosine kinases: promising tools for targeted cancer therapies by Hojjat-Farsangi, Mohammad

“…Chemotherapeutic and cytotoxic drugs are widely used in the treatment of cancer. In spite of the improvements in the life quality of patients, their…”
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A ROR1 small molecule inhibitor (KAN0441571C) induced significant apoptosis of ibrutinib‐resistant ROR1+ CLL cells by Ghaderi, Amineh, Okhovat, Mohammad‐Ali, Wikanthi, Layung Sekar Sih, Svensson, Ann, Palma, Marzia, Schultz, Johan, Olin, Thomas, Österborg, Anders, Mellstedt, Håkan, Hojjat‐Farsangi, Mohammad

“…ROR1 – a receptor tyrosine kinase – is overexpressed in CLL. Ibrutinib, a Bruton's tyrosine kinase inhibitor, is clinically effective in CLL but patients may…”
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Immunoglobulin heavy chain variable region gene usage and mutational status of the leukemic B cells in Iranian patients with chronic lymphocytic leukemia by Hojjat‐Farsangi, Mohammad, Jeddi‐Tehrani, Mahmood, Razavi, Seyed Mohsen, Sharifian, Ramazan Ali, Mellstedt, Hakan, Shokri, Fazel, Rabbani, Hodjatallah

“…The mutational status of the immunoglobulin variable region heavy chain genes (IGHV) is an important prognostic marker in chronic lymphocytic leukemia (CLL)…”
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The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer by Masjedi, Ali, Hashemi, Vida, Hojjat-Farsangi, Mohammad, Ghalamfarsa, Ghasem, Azizi, Gholamreza, Yousefi, Mehdi, Jadidi-Niaragh, Farhad

“…•IL-6 and its associated signaling promote cancer progression.•Targeting IL-6 signaling axis can arrest tumor growth.•Blockage of IL-6 and IL-6R can be…”
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Prostaglandin E2 as a potent therapeutic target for treatment of colon cancer by Karpisheh, Vahid, Nikkhoo, Afshin, Hojjat-Farsangi, Mohammad, Namdar, Afshin, Azizi, Gholamreza, Ghalamfarsa, Ghasem, Sabz, Gholamabas, Yousefi, Mehdi, Yousefi, Bahman, Jadidi-Niaragh, Farhad

“…•Colon cancer in one of the main health-related problems which is incurable particularly in advanced stages.•Prostanoids and particularly prostaglandin E2…”
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