Search Results - "Hohos, Natalie M"
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High-Fat Diet and Female Fertility
Published in Endocrinology (Philadelphia) (01-08-2017)“…Abstract The prevalence of obesity is high among reproductive-age women and is associated with impaired reproductive function. Obesity is multifactorial in…”
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Synergistic Phytochemicals Fail to Protect Against Ovariectomy Induced Bone Loss in Rats
Published in Journal of medicinal food (01-10-2018)“…Menopause induces a loss of bone as a result of estrogen deficiency. Despite pharmaceutical options for the treatment of osteopenia and osteoporosis, many…”
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High-fat diet exposure, regardless of induction of obesity, is associated with altered expression of genes critical to normal ovulatory function
Published in Molecular and cellular endocrinology (15-07-2018)“…We evaluated the impact of high-fat diet (HFD) on ovarian gene expression. Female 5-week-old C57BL/6J mice were fed a 60% HFD or standard chow for 10 weeks…”
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High-fat diet-induced dysregulation of ovarian gene expression is restored with chronic omega-3 fatty acid supplementation
Published in Molecular and cellular endocrinology (01-01-2020)“…Chronic high-fat diet (HFD) consumption causes ovarian dysfunction in rodents. Acute dietary treatment with docosahexaenoic acid (DHA) increases oocyte quality…”
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High-fat diet induces an ovulatory defect associated with dysregulated endothelin-2 in mice
Published in Reproduction (Cambridge, England) (01-03-2021)“…High-fat diet (HFD) consumption in female rodents causes impaired estrous cyclicity, fewer pups per litter, and dysregulation of key ovulatory genes suggesting…”
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Fat-1 Transgene Is Associated With Improved Reproductive Outcomes
Published in Endocrinology (Philadelphia) (01-12-2018)“…High intake of ω-3 polyunsaturated fatty acids (PUFAs) has been associated with a variety of health benefits. However, the role of ω-3 PUFAs in female…”
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CD4+ and CD8+ T‐Cell‐Specific DNA Cytosine Methylation Differences Associated With Obesity
Published in Obesity (Silver Spring, Md.) (01-08-2018)“…Objective Lifestyle factors associated with obesity may alter epigenome‐regulated gene expression. Most studies examining epigenetic changes in obesity have…”
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DNA cytosine hydroxymethylation levels are distinct among non-overlapping classes of peripheral blood leukocytes
Published in Journal of immunological methods (01-09-2016)“…Peripheral blood leukocytes are the most commonly used surrogates to study epigenome-induced risk and epigenomic response to disease-related stress. We…”
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Distinctions in gene-specific changes in DNA methylation in response to folic acid supplementation between women with normal weight and obesity
Published in Obesity research & clinical practice (01-11-2017)“…Obesity and maternal folate deficiency are associated with increased risk for neural tube defects (NTDs). Limited knowledge exists on the impact of folate…”
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High-fat diet causes dysregulation of ovarian endothelin-2 expression across the estrous cycle
Published in Fertility and sterility (01-09-2019)Get full text
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High-fat diet leads to increased ovarian lipid deposition even in the absence of obesity
Published in Fertility and sterility (01-09-2019)Get full text
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CD4^sup +^ and CD8^sup +^ T-Cell-Specific DNA Cytosine Methylation Differences Associated With Obesity
Published in Obesity (Silver Spring, Md.) (01-08-2018)“…Lifestyle factors associated with obesity may alter epigenome-regulated gene expression. Most studies examining epigenetic changes in obesity have analyzed DNA…”
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Differential DNA Methylation between Obese and Normal Weight Women in CD4+ and CD8+ T cells, and CD16+ neutrophils
Published in The FASEB journal (01-04-2016)“…Abstract only Diet, nutrition, and perhaps other lifestyle factors are proposed to alter chromatin structures such as DNA cytosine modification and…”
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