Search Results - "Hohn, T.M"

Aristolochene synthase: isolation, characterization, and bacterial expression of a sesquiterpenoid biosynthetic gene (Ari1) from Penicillium roqueforti by Proctor, R.H. (USDA, ARS, National Center for Agricultural Utilization Research, Peoria, IL), Hohn, T.M

“…Aristolochene is the likely precursor of the sesquiterpenoid toxins produced by a number of filamentous fungi. One of these, PR-toxin, is produced by…”
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Overproduction of soluble trichodiene synthase from Fusarium sporotrichioides in Escherichia coli by Cane, D E, Wu, Z, Oliver, J S, Hohn, T M

“…Trichodiene synthase is a sesquiterpene cyclase isolated from various fungal species which catalyzes the cyclization of farnesyl diphosphate (FPP) to…”
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Overexpression in Escherichia coli of soluble aristolochene synthase from Penicillium roqueforti by Cane, D E, Wu, Z, Proctor, R H, Hohn, T M

“…Aristolochene synthase, a fungal cyclase which has been isolated from Aspergillus terreus and Penicillium roqueforti, catalyzes the cyclization of farnesyl…”
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Metabolic Pathway Gene Clusters in Filamentous Fungi by Keller, Nancy P., Hohn, Thomas M.

“…Clusters of functionally related genes are a general feature of prokaryotic gene organization but are much less prevalent in eukaryotes. The discovery that…”
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A Polyketide Synthase Gene Required for Biosynthesis of Fumonisin Mycotoxins in Gibberella fujikuroi Mating Population A by Proctor, Robert H, Desjardins, Anne E, Plattner, Ronald D, Hohn, Thomas M

“…Fumonisins are toxins associated with several mycotoxicoses and are produced by the maize pathogen Gibberella fujikuroi mating population A (MP-A). Biochemical…”
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Reduced virulence of Gibberella zeae caused by disruption of a trichothecene toxin biosynthetic gene by Proctor, R.H. (Mycotoxin Research Unit, USDA/ARS, National Center for Agriculture Utilization Research, Peoria, IL.), Hohn, T.M, McCormick, S.P

“…The production of trichothecene mycotoxins by some plant pathogenic species of Fusarium is thought to contribute to their virulence. Gibberella zeae (F…”
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Reduced virulence of trichothecene-nonproducing mutants of Gibberella zeae in wheat field tests by Desiardins, A.E. (National Center for Agricultural Utilization Research, USDA, ARS, Peoria, IL.), Proctor, R.H, Bai, G, McCormick, S.P, Shaner, G, Buechley, G, Hohn, T.M

“…We have analyzed the role of trichothecene toxins in the virulence of the fungus Gibberella zeae (anamorph, Fusarium graminearum) on wheat (Triticum aestivum)…”
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Expression of 3-OH trichothecene acetyltransferase in barley ( Hordeum vulgare L.) and effects on deoxynivalenol by Manoharan, Muthusamy, Dahleen, Lynn S., Hohn, Thomas M., Neate, Stephen M., Yu, Xiao-Hong, Alexander, Nancy J., McCormick, Susan P., Bregitzer, Phil, Schwarz, Paul B., Horsley, Richard D.

“…Fusarium head blight (FHB), caused primarily by Fusarium graminearum, has been the most destructive disease of barley ( Hordeum vulgare L.) in the USA since…”
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Use of Fusarium graminearum transformed with gfp to follow infection patterns in barley and Arabidopsis by Skadsen, Ronald W, Hohn, Thomas M

“…The fungal pathogen Fusarium graminearum attacks the seed spikes of barley and wheat, causing sterility, reduced seed weight and accumulation of mycotoxins. To…”
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Mycotoxins in plant pathogenesis by Desjardins, A.E. (National Center for Agricultural Utilization Research, USDA, ARS, Peoria, IL.), Hohn, T.M

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Trichothecene biosynthesis in Fusarium species: chemistry, genetics, and significance by Desjardins, A.E, Hohn, T.M, McCormick, S.P

“…Several species of the genus Fusarium and related fungi produce trichothecenes which are sesquiterpenoid epoxides that act as potent inhibitors of eukaryotic…”
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The TRI11 gene of fusarium sporotrichioides encodes a cytochrome P-450 monooxygenase required for C-15 hydroxylation in trichothecene biosynthesis by Alexander, N.J, Hohn, T.M, McCormick, S.P

“…Several genes in the trichothecene biosynthetic pathway of Fusarium sporotrichioides have been shown to reside in a gene cluster. Sequence analysis of a cloned…”
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Characterization of a Transcriptional Activator Controlling Trichothecene Toxin Biosynthesis by Hohn, Thomas M, Krishna, Roopa, Proctor, Robert H

“…Trichothecene biosynthetic pathway genes are localized within a gene cluster in Fusarium sporotrichioides and require the zinc-finger containing protein, TRI6,…”
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Engineering deoxynivalenol metabolism in wheat through the expression of a fungal trichothecene acetyltransferase gene by OKUBARA, P. A, BLECHL, A. E, MCCORMICK, S. P, ALEXANDER, N. J, DILL-MACKY, R, HOHN, T. M

“…Fusarium head blight occurs in cereals throughout the world and is especially important in humid growing regions. Fusarium head blight (FHB) has re-emerged as…”
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identification of the Saccharomyces cerevisiae gene AYT1(ORF-YLL063c) encoding an acetyltransferase by Alexander, N.J, McCormick, S.P, Hohn, T.M

“…The recent isolation and characterization of Tri101 in Fusarium sporotrichioides has led to the functional identification of the yeast open reading frame (ORF)…”
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Isolation and characterization of Tri3, a gene encoding 15-O-acetyltransferase from Fusarium sporotrichioides by McCormick, S.P. (USDA, ARS, NCAUR, Peoria, IL.), Hohn, T.M, Desjardins, A.E

“…An acetyltransferase gene (Tri3) was isolated from Fusarium sporotrichioides by complementation of a previously identified Tri3- mutant and shown to be closely…”
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Isolation and gene disruption of the Tox5 gene encoding trichodiene synthase in Gibberella pulicaris by HOHN, T. M, DESJARDINS, A. E

“…The trichodiene synthase gene (Tox5) was isolated from Gibberella pulicaris, and its nucleotide sequence was determined. Tox5 was disrupted through…”
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Accumulation of trichothecenes in liquid cultures of a Fusarium sporotrichioides mutant lacking a functional trichothecene C-15 hydroxylase by McCormick, S.P, Hohn, T.M

“…A mutant strain of Fusarium sporotrichioides NRRL 3299 produced by disruption of Tri11, a gene encoding a cytochrome P-450 monooxygenase, was shown to be…”
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Evidence for a gene cluster involving trichothecene-pathway biosynthetic genes in Fusarium sporotrichioides by Hohn, T.M. (United States Dept. of Agriculture/Agricultural Research Service, Peoria, IL (USA). National Center for Agricultural Utilization Research. Mycotoxin Research Unit), McCormick, S.P, Desjardins, A.E

“…Two overlapping cosmid clones (Cos1-1 and Cos9-1) carrying the Tox5 gene were isolated from a library of Fusarium sporotrichioides strain NRRL 3299 genomic…”
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Tri6 encodes an unusual zinc finger protein involved in regulation of trichotecene biosynthesis in Fusarium sporotrichioides by Proctor, R.H, Hohn, T.M, McCormick, S.P, Desjardins, A.E

“…In Fusarium sporotrichioides, several genes required for biosynthesis of the trichothecene mycotoxin T-Z toxin are closely linked. Further characterization of…”
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