Search Results - "Hohmann, Urszula"

MACC1-induced migration in tumors: Current state and perspective by Hohmann, Tim, Hohmann, Urszula, Dehghani, Faramarz

“…Malignant tumors are still a global, heavy health burden. Many tumor types cannot be treated curatively, underlining the need for new treatment targets. In…”
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Analyzing the Impact of the Highest Expressed Epstein-Barr Virus-Encoded microRNAs on the Host Cell Transcriptome by Hohmann, Tim, Hohmann, Urszula, Dehghani, Faramarz, Grisk, Olaf, Jasinski-Bergner, Simon

“…The Epstein-Barr virus (EBV) has a very high prevalence (>90% in adults), establishes a lifelong latency after primary infection, and exerts an oncogenic…”
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Assessment of Neuronal Damage in Brain Slice Cultures Using Machine Learning Based on Spatial Features by Hohmann, Urszula, Dehghani, Faramarz, Hohmann, Tim

“…Neuronal damage presents a major health issue necessitating extensive research to identify mechanisms of neuronal cell death and potential therapeutic targets…”
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A toolbox to analyze collective cell migration, proliferation and cellular organization simultaneously by Hohmann, Urszula, Ghadban, Chalid, Prell, Julian, Strauss, Christian, Dehghani, Faramarz, Hohmann, Tim

“…Analyses of collective cell migration and orientation phenomena are needed to assess the behavior of multicellular clusters. While some tools to the authors'…”
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Opposite Effects of Neuroprotective Cannabinoids, Palmitoylethanolamide, and 2-Arachidonoylglycerol on Function and Morphology of Microglia by Hohmann, Urszula, Pelzer, Markus, Kleine, Joshua, Hohmann, Tim, Ghadban, Chalid, Dehghani, Faramarz

“…Various studies performed in cultured cells and in in vivo models of neuronal damage showed that cannabinoids exert a neuroprotective effect. The increase in…”
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Nimodipine Exerts Time-Dependent Neuroprotective Effect after Excitotoxical Damage in Organotypic Slice Cultures by Hohmann, Urszula, Ghadban, Chalid, Hohmann, Tim, Kleine, Joshua, Schmidt, Miriam, Scheller, Christian, Strauss, Christian, Dehghani, Faramarz

“…During injuries in the central nervous system, intrinsic protective processes become activated. However, cellular reactions, especially those of glia cells,…”
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MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma by Hohmann, Tim, Hohmann, Urszula, Kolbe, Marc R, Dahlmann, Mathias, Kobelt, Dennis, Stein, Ulrike, Dehghani, Faramarz

“…Metastasis-associated in colon cancer 1 (MACC1) is an established marker for metastasis and tumor cell migration in a multitude of tumor entities, including…”
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Microglia-Dependent and Independent Brain Cytoprotective Effects of Mycophenolate Mofetil During Neuronal Damage by Kleine, Joshua, Hohmann, Urszula, Hohmann, Tim, Ghadban, Chalid, Schmidt, Miriam, Laabs, Sebastian, Alessandri, Beat, Dehghani, Faramarz

“…Acute lesions of the central nervous system often lead to permanent limiting deficits. In addition to the initial primary damage, accompanying…”
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Interaction of Glia Cells with Glioblastoma and Melanoma Cells under the Influence of Phytocannabinoids by Hohmann, Urszula, Walsleben, Christoph, Ghadban, Chalid, Kirchhoff, Frank, Dehghani, Faramarz, Hohmann, Tim

“…Brain tumor heterogeneity and progression are subject to complex interactions between tumor cells and their microenvironment. Glioblastoma and brain metastasis…”
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Elucidation of GPR55-Associated Signaling behind THC and LPI Reducing Effects on Ki67-Immunoreactive Nuclei in Patient-Derived Glioblastoma Cells by Kolbe, Marc Richard, Hohmann, Tim, Hohmann, Urszula, Maronde, Erik, Golbik, Ralph, Prell, Julian, Illert, Jörg, Strauss, Christian, Dehghani, Faramarz

“…GPR55 is involved in many physiological and pathological processes. In cancer, GPR55 has been described to show accelerating and decelerating effects in tumor…”
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Jamming Transitions in Astrocytes and Glioblastoma Are Induced by Cell Density and Tension by Hohmann, Urszula, von Widdern, Julian Cardinal, Ghadban, Chalid, Giudice, Maria Cristina Lo, Lemahieu, Grégoire, Cavalcanti-Adam, Elisabetta Ada, Dehghani, Faramarz, Hohmann, Tim

“…Collective behavior of cells emerges from coordination of cell-cell-interactions and is important to wound healing, embryonic and tumor development. Depending…”
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Adrenergic Agonists Activate Transcriptional Activity in Immortalized Neuronal Cells From the Mouse Suprachiasmatic Nucleus by Langiu, Monica, Dehghani, Faramarz, Hohmann, Urszula, Bechstein, Philipp, Rawashdeh, Oliver, Rami, Abdelhaq, Maronde, Erik

“…ABSTRACT The suprachiasmatic nucleus of the hypothalamus (SCN) houses the central circadian oscillator of mammals. The main neurotransmitters produced in the…”
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MACC1-Induced Collective Migration Is Promoted by Proliferation Rather Than Single Cell Biomechanics by Hohmann, Tim, Hohmann, Urszula, Dahlmann, Mathias, Kobelt, Dennis, Stein, Ulrike, Dehghani, Faramarz

“…Metastasis-associated in colon cancer 1 (MACC1) is a marker for metastasis, tumor cell migration, and increased proliferation in colorectal cancer (CRC)…”
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Radiosensitization and a Less Aggressive Phenotype of Human Malignant Glioma Cells Expressing Isocitrate Dehydrogenase 1 (IDH1) Mutant Protein: Dissecting the Mechanisms by Kessler, Jacqueline, Hohmann, Tim, Güttler, Antje, Petrenko, Marina, Ostheimer, Christian, Hohmann, Urszula, Bache, Matthias, Dehghani, Faramarz, Vordermark, Dirk

“…The presence of an isocitrate dehydrogenase 1 (IDH1) mutation is associated with a less aggressive phenotype, increased sensitivity to radiation, and increased…”
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THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner by Kolbe, Marc Richard, Hohmann, Tim, Hohmann, Urszula, Ghadban, Chalid, Mackie, Ken, Zöller, Christin, Prell, Julian, Illert, Jörg, Strauss, Christian, Dehghani, Faramarz

“…Glioblastoma (GBM) is the most frequent malignant tumor of the central nervous system in humans with a median survival time of less than 15 months. ∆…”
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