Search Results - "Hohlbaum, A"

engineered lipocalin specific for CTLA-4 reveals a combining site with structural and conformational features similar to antibodies by Schönfeld, D, Matschiner, G, Chatwell, L, Trentmann, S, Gille, H, Hülsmeyer, M, Brown, N, Kaye, P.M, Schlehuber, S, Hohlbaum, A.M, Skerra, A

“…Biomolecular reagents that enable the specific molecular recognition of proteins play a crucial role in basic research as well as medicine. Up to now,…”
Get full text

Fas Ligand Engagement of Resident Peritoneal Macrophages In Vivo Induces Apoptosis and the Production of Neutrophil Chemotactic Factors by Hohlbaum, Andreas M, Gregory, Meredith S, Ju, Shyr-Te, Marshak-Rothstein, Ann

“…Fas ligand (FasL) is a potent proapoptotic type-II transmembrane protein that can cause cell death in Fas+ target populations. Despite the presumed "silent"…”
Get full text

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors by Leadbetter, Elizabeth A, Rifkin, Ian R, Hohlbaum, Andreas M, Beaudette, Britte C, Shlomchik, Mark J, Marshak-Rothstein, Ann

“…Autoreactive B cells are present in the lymphoid tissues of healthy individuals, but typically remain quiescent. When this homeostasis is perturbed, the…”
Get full text

Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival by Hohlbaum, A M, Moe, S, Marshak-Rothstein, A

“…Fas ligand (FasL) has been shown to mediate both apoptotic and inflammatory reactions. To rigorously assess the physiological role of different forms of the…”
Get full text

CD95 (Fas) Ligand-Expressing Vesicles Display Antibody-Mediated, FcR-Dependent Enhancement of Cytotoxicity by Jodo, Satoshi, Hohlbaum, Andreas M, Xiao, Sheng, Chan, Derek, Strehlow, David, Sherr, David H, Marshak-Rothstein, Ann, Ju, Shyr-Te

“…Bioactive Fas ligand (FasL)-expressing vesicles were generated (vesicle preparation, VP) from two cell lines overexpressing FasL. The effect of NOK-1 anti-FasL…”
Get full text

Fas-Ligand—Iron Fist or Achilles' Heel? by Hohlbaum, Andreas M., Saff, Rebecca R., Marshak-Rothstein, Ann

“…Experimental and physiological expression of the pro-apoptotic molecule Fas-ligand can induce inflammation under certain conditions. Discussed here are the…”
Get full text

D33 AIRWAY EPITHELIA ACTIVATION AND RESPONSES TO TREATMENT: Interleukin-13 As A Therapeutic Target For Allergic Asthma Tested In Human Precision-Cut Lung Slices by Danov, O, Jimenez, S, Pfennig, O, ster, C, Hohlbaum, A, Audoly, L, Braun, A, Sewald, K

Get full text

The B cell repertoire of patients with rheumatoid arthritis. Frequencies and specificities of peripheral blood B cells reacting with human IgG, human collagens, a mycobacterial heat shock protein and other antigens by RUDOLPHI, U., HOHLBAUM, A., LANG, B., PETER, H. H., MELCHERS, I.

“…SUMMARY Using a potent in vitro limiting dilution culture system, we have activated human peripheral blood B cells to proliferate and to differentiate into…”
Get full text

Structure and expression of a non-polyadenylated ribosome bound transcript carrying the sequence of human ribosomal protein L7 mRNA in antisense orientation by Hohlbaum, A M, Krawinkel, U, Hemmerich, P

“…Human ribosomal protein L7 has been shown to be involved in the control of translation of distinct mRNAs. In this study we report the existence of an RNA…”
Get more information

Apoptosis-inducing membrane vesicles. A novel agent with unique properties by Jodo, S, Xiao, S, Hohlbaum, A, Strehlow, D, Marshak-Rothstein, A, Ju, S T

“…The CD95 ligand (FasL) transmembrane protein is found on activated T cells and cells outside the immune system. A well-known turnover process of membrane FasL…”
Get full text

Activation-Induced Cell Death Limits Effector Function of CD4 Tumor-Specific T Cells by Saff, Rebecca R, Spanjaard, Elena S, Hohlbaum, Andreas M, Marshak-Rothstein, Ann

“…A number of studies have documented a critical role for tumor-specific CD4(+) cells in the augmentation of immunotherapeutic effector mechanisms. However, in…”
Get full text

The B cell repertoire of patients with rheumatoid arthritis. Frequencies and specificities of peripheral blood B cells reacting with human IgC, human collagens, a mycobacterial heat shock protein and other antigens by RUDOLPHI, U, HOHLBAUM, A, LANG, B, PETER, H. H, MELCHERS, I

Get full text