Search Results - "Hoglund, M"

COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacology by White, Nicholas J, Watson, James A, Hoglund, Richard M, Chan, Xin Hui S, Cheah, Phaik Yeong, Tarning, Joel

“…Nicholas White and coauthors discuss chloroquine and hydroxychloroquine pharmacology in the context of possible treatment of SARS-CoV-2 infection…”
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The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern by Abdelnabi, Rana, Foo, Caroline S., Jochmans, Dirk, Vangeel, Laura, De Jonghe, Steven, Augustijns, Patrick, Mols, Raf, Weynand, Birgit, Wattanakul, Thanaporn, Hoglund, Richard M., Tarning, Joel, Mowbray, Charles E., Sjö, Peter, Escudié, Fanny, Scandale, Ivan, Chatelain, Eric, Neyts, Johan

“…There is an urgent need for potent and selective antivirals against SARS-CoV-2. Pfizer developed PF-07321332 (PF-332), a potent inhibitor of the viral main…”
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Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside by Assmus, Frauke, Hoglund, Richard M, Monnot, Frédéric, Specht, Sabine, Scandale, Ivan, Tarning, Joel

“…To accelerate the progress towards onchocerciasis elimination, a macrofilaricidal drug that kills the adult parasite is urgently needed. Emodepside has shown…”
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Population pharmacokinetic modelling of primaquine exposures in lactating women and breastfed infants by Wattanakul, Thanaporn, Gilder, Mary Ellen, McGready, Rose, Hanpithakpong, Warunee, Day, Nicholas P. J., White, Nicholas J., Nosten, François, Tarning, Joel, Hoglund, Richard M.

“…Current guidelines advise against primaquine treatment for breastfeeding mothers to avoid the potential for haemolysis in infants with G6PD deficiency. To…”
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Medication adherence framework: A population‐based pharmacokinetic approach and its application in antimalarial treatment assessments by Ding, Junjie, Hoglund, Richard M., Tarning, Joel

“…We reported here on the development of a pharmacometric framework to assess patient adherence, by using two population‐based approaches – the percentile and…”
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Severe Acute Malnutrition Results in Lower Lumefantrine Exposure in Children Treated With Artemether‐Lumefantrine for Uncomplicated Malaria by Chotsiri, Palang, Denoeud‐Ndam, Lise, Baudin, Elisabeth, Guindo, Ousmane, Diawara, Halimatou, Attaher, Oumar, Smit, Michiel, Guerin, Philippe J., Doumbo, Ogobara K., Wiesner, Lubbe, Barnes, Karen I., Hoglund, Richard M., Dicko, Alassane, Etard, Jean‐Francois, Tarning, Joel

“…Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub‐Saharan African children and may affect the…”
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Associations between bladder cancer molecular subtypes and metastatic sites by Sjödahl, G., Eriksson, P., Holmsten, K., Abrahamsson, J., Höglund, M., Bernardo, C., Ullén, A., Liedberg, F.

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Safety and pharmacokinetic properties of a new formulation of parenteral artesunate in healthy Thai volunteers by Tarning, Joel, Hanboonkunupakarn, Borimas, Hoglund, Richard M, Chotivanich, Kesinee, Mukaka, Mavuto, Pukrittayakamee, Sasithon, Day, Nicholas P J, White, Nicholas J, Dondorp, Arjen M, Jittamala, Podjanee

“…Parenteral artesunate is the first-line therapy for severe malaria. Artesunate, in its current formulation, must be prepared immediately before administration…”
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Concentration-dependent mortality of chloroquine in overdose by Watson, James A, Tarning, Joel, Hoglund, Richard M, Baud, Frederic J, Megarbane, Bruno, Clemessy, Jean-Luc, White, Nicholas J

“…Hydroxychloroquine and chloroquine are used extensively in malaria and rheumatological conditions, and now in COVID-19 prevention and treatment. Although…”
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Population pharmacokinetics of mefloquine given as a 3-day artesunate-mefloquine in patients with acute uncomplicated Plasmodium falciparum malaria in a multidrug-resistant area along the Thai-Myanmar border by Hoglund, Richard M, Ruengweerayut, Ronnatrai, Na-Bangchang, Kesara

“…Low mefloquine exposure has been shown to contribute to treatment failure in patients with uncomplicated falciparum malaria following a 3-day…”
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Characterization of therapy-related acute myeloid leukemia: increasing incidence and prognostic implications by Nilsson, Christer, Linde, Fredrika, Hulegårdh, Erik, Garelius, Hege, Lazarevic, Vladimir, Antunovic, Petar, Cammenga, Jörg, Deneberg, Stefan, Eriksson, Anna, Jädersten, Martin, Björkvall, Cecilia Kämpe, Möllgård, Lars, Wennström, Lovisa, Ölander, Emma, Höglund, Martin, Juliusson, Gunnar, Lehmann, Sören

“…Studies of therapy-related AML (t-AML) are usually performed in selected cohorts and reliable incidence rates are lacking. In this study, we characterized,…”
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Proteogenomic analysis of acute myeloid leukemia associates relapsed disease with reprogrammed energy metabolism both in adults and children by Stratmann, Svea, Vesterlund, Mattias, Umer, Husen M., Eshtad, Saeed, Skaftason, Aron, Herlin, Morten Krogh, Sundström, Christer, Eriksson, Anna, Höglund, Martin, Palle, Josefine, Abrahamsson, Jonas, Jahnukainen, Kirsi, Munthe-Kaas, Monica Cheng, Zeller, Bernward, Tamm, Katja Pokrovskaja, Lindskog, Cecilia, Cavelier, Lucia, Lehtiö, Janne, Holmfeldt, Linda

“…Despite improvement of current treatment strategies and novel targeted drugs, relapse and treatment resistance largely determine the outcome for acute myeloid…”
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Targeting SAMHD1 with hydroxyurea in first‐line cytarabine‐based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT‐AML trial by Jädersten, Martin, Lilienthal, Ingrid, Tsesmetzis, Nikolaos, Lourda, Magda, Bengtzén, Sofia, Bohlin, Anna, Arnroth, Cornelia, Erkers, Tom, Seashore‐Ludlow, Brinton, Giraud, Géraldine, Barkhordar, Giti S., Tao, Sijia, Fogelstrand, Linda, Saft, Leonie, Östling, Päivi, Schinazi, Raymond F., Kim, Baek, Schaller, Torsten, Juliusson, Gunnar, Deneberg, Stefan, Lehmann, Sören, Rassidakis, Georgios Z., Höglund, Martin, Henter, Jan‐Inge, Herold, Nikolas

“…Background Treatment of newly diagnosed acute myeloid leukaemia (AML) is based on combination chemotherapy with cytarabine (ara‐C) and anthracyclines…”
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Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria by Taylor, Walter Robert, Hoglund, Richard M, Peerawaranun, Pimnara, Nguyen, Thuy Nhien, Hien, Tran Tinh, Tarantola, Arnaud, von Seidlein, Lorenz, Tripura, Rupam, Peto, Thomas J, Dondorp, Arjen M, Landier, Jordi, H Nosten, Francois, Smithuis, Frank, Phommasone, Koukeo, Mayxay, Mayfong, Kheang, Soy Ty, Say, Chy, Neeraj, Kak, Rithea, Leang, Dysoley, Lek, Kheng, Sim, Muth, Sinoun, Roca-Feltrer, Arantxa, Debackere, Mark, Fairhurst, Rick M, Song, Ngak, Buchy, Philippe, Menard, Didier, White, Nicholas J, Tarning, Joel, Mukaka, Mavuto

“…In many endemic areas, Plasmodium vivax malaria is predominantly a disease of young adults and children. International recommendations for radical cure…”
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Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets by Stratmann, Svea, Yones, Sara A., Mayrhofer, Markus, Norgren, Nina, Skaftason, Aron, Sun, Jitong, Smolinska, Karolina, Komorowski, Jan, Herlin, Morten Krogh, Sundström, Christer, Eriksson, Anna, Höglund, Martin, Palle, Josefine, Abrahamsson, Jonas, Jahnukainen, Kirsi, Munthe-Kaas, Monica Cheng, Zeller, Bernward, Tamm, Katja Pokrovskaja, Cavelier, Lucia, Holmfeldt, Linda

“…Relapse is the leading cause of death of adult and pediatric patients with acute myeloid leukemia (AML). Numerous studies have helped to elucidate the complex…”
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National and regional incidence of surgery for adult hydrocephalus in Sweden by Tisell, M., Höglund, M., Wikkelsø, C.

“…In Sweden, the annual incidence of surgery for hydrocephalus was 3.4 per 100,000 adults between the years 1996 and 1998. The most common indication for surgery…”
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Pre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2 by Driouich, Jean-Sélim, Cochin, Maxime, Touret, Franck, Petit, Paul-Rémi, Gilles, Magali, Moureau, Grégory, Barthélémy, Karine, Laprie, Caroline, Wattanakul, Thanaporn, Chotsiri, Palang, Hoglund, Richard M., Tarning, Joel, Fraisse, Laurent, Sjö, Peter, Mowbray, Charles E., Escudié, Fanny, Scandale, Ivan, Chatelain, Eric, de Lamballerie, Xavier, Solas, Caroline, Nougairède, Antoine

“…To address the emergence of SARS-CoV-2, multiple clinical trials in humans were rapidly started, including those involving an oral treatment by nitazoxanide,…”
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A randomised trial of malaria vaccine R21/Matrix-M™ with and without antimalarial drugs in Thai adults by Hanboonkunupakarn, Borimas, Mukaka, Mavuto, Jittamala, Podjanee, Poovorawan, Kittiyod, Pongsuwan, Pongphaya, Stockdale, Lisa, Provstgaard-Morys, Samuel, Chotivanich, Kesinee, Tarning, Joel, Hoglund, Richard M., Chimjinda, Natenapa, Ewer, Katie, Ramos-Lopez, Fernando, Day, Nicholas P. J., Dondorp, Arjen M., Hill, Adrian V., White, Nicholas J., von Seidlein, Lorenz, Pukrittayakamee, Sasithon

“…In preparation for mass vaccinations with R21/Matrix-M™ combined with mass administrations of dihydroartemisinin, piperaquine, and a single low dose primaquine…”
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A population pharmacokinetic model of piperaquine in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Sudan by Hoglund, Richard M, Adam, Ishag, Hanpithakpong, Warunee, Ashton, Michael, Lindegardh, Niklas, Day, Nicholas P J, White, Nicholas J, Nosten, Francois, Tarning, Joel

“…Pregnancy is associated with an increased risk of developing a malaria infection and a higher risk of developing severe malaria. The pharmacokinetic properties…”
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Combining antimalarial drugs and vaccine for malaria elimination campaigns: a randomized safety and immunogenicity trial of RTS,S/AS01 administered with dihydroartemisinin, piperaquine, and primaquine in healthy Thai adult volunteers by von Seidlein, Lorenz, Hanboonkunupakarn, Borimas, Jittamala, Podjanee, Pongsuwan, Pongphaya, Chotivanich, Kesinee, Tarning, Joel, Hoglund, Richard M., Winterberg, Markus, Mukaka, Mavuto, Peerawaranun, Pimnara, Sirithiranont, Pasathorn, Doran, Zoe, Ockenhouse, Christian F., Ivinson, Karen, Lee, Cynthia, Birkett, Ashley J., Kaslow, David C., Singhasivanon, Pratap, Day, Nicholas P.J., Dondorp, Arjen M., White, Nicholas J., Pukrittayakamee, Sasithon

“…Introduction: RTS,S/AS01 is currently the most advanced malaria vaccine but provides incomplete, short-term protection. It was developed for use within the…”
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